(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine is a chiral morpholine derivative with the molecular formula C20H33NO and a molecular weight of 303.5 g/mol. This organic compound features a morpholine ring substituted with dimethyl groups and a complex alkylphenyl side chain containing a tert-butyl group. The CAS number 67564-91-4 uniquely identifies this stereoisomer, which exhibits specific optical activity due to its defined stereochemistry at positions 2S and 6R.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine is an organic compound with molecular formula C20H33NO and molecular weight 303.5 g/mol. As a substituted morpholine derivative containing both aromatic and aliphatic components, it likely exists as a liquid or low-melting solid at room temperature. The presence of the morpholine nitrogen atom suggests basic properties, while the bulky tert-butylphenyl group influences its solubility characteristics and physical behavior.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine serves as an important chemical intermediate in pharmaceutical and fine chemical synthesis. Its morpholine structure and specific stereochemistry make it valuable for developing active pharmaceutical ingredients and specialty chemicals. The compound's unique molecular architecture allows it to function as a building block in medicinal chemistry applications, particularly where stereospecific activity is required. Industrial applications may include use as a synthetic precursor or catalyst component.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine requires careful handling due to its Acute Tox. 4 and Skin Irrit. 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume extraction to avoid inhalation. The substance carries GHS07 and GHS08 pictograms with a Warning signal word, indicating moderate but significant health hazards requiring appropriate safety measures.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Given its reproductive toxicity (Repr. 2) and skin irritation properties, storage areas must be clearly labeled and access restricted to trained personnel. Keep containers upright and protected from physical damage. Due to its Aquatic Chronic 2 classification, ensure secondary containment to prevent environmental release.

Immediate action is required following contact with (2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2-6-dimethylmorpholine due to its skin irritant and toxic properties. For skin contact, immediately remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek medical attention. If inhaled, move to fresh air immediately. Given the Acute Tox. 4 classification, seek immediate medical advice for any significant exposure.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine must be disposed of through licensed hazardous waste management companies in compliance with local and EU regulations. The substance's Aquatic Chronic 2 classification requires particular care to prevent environmental contamination. Waste should be collected in appropriate containers, clearly labeled, and never discharged to sewers or water bodies. Container disposal must also follow hazardous waste protocols. Consult local authorities for specific disposal requirements in your region.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires appropriate UN-specification packaging, proper labeling with Class 9 hazard labels, and accompanying transport documentation. Vehicles must carry appropriate emergency equipment and drivers need ADR training. The Packing Group III designation indicates moderate danger during transport, but still requires compliance with dangerous goods regulations.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine is subject to EU CLP regulation due to its hazard classifications including Repr. 2, Acute Tox. 4, and Skin Irrit. 2. While not currently listed as an SVHC under REACH, it requires proper classification, labeling, and safety data sheets. The substance's reproductive toxicity classification may trigger additional workplace restrictions and handling requirements. Companies must ensure compliance with occupational exposure limits and provide appropriate worker protection measures.

(2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to qualified industrial and research customers with proper documentation and regulatory compliance support. As a controlled substance requiring specialized handling, purchases are typically restricted to professional users with appropriate facilities and training. Contact OYSI directly for availability, specifications, and regulatory documentation required for your specific application.