Propan-2-one

C3H6O

propan-2-one

CAS67-64-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

Consulting for Propan-2-one

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
67-64-1
EC Number
200-662-2
UN Number
1090
Index Number
606-001-00-8
PubChem CID
180

Physical-chemical properties

Molecular Formula
C3H6O
Molar Mass
58.08 g/mol
IUPAC Name
propan-2-one

Chemical Identifiers

InChI
InChI=1S/C3H6O/c1-3(2)4/h1-2H3
InChI Key
CSCPPACGZOOCGX-UHFFFAOYSA-N

Overview

Propan-2-one (CAS 67-64-1) is a ketone solvent with high volatility and excellent dissolving properties for various organic compounds. This versatile organic solvent, commonly known as acetone, represents one of the most widely used ketones in industrial applications across Europe. With its molecular formula C3H6O and relatively low molecular weight of 58.08 g/mol, propan-2-one exhibits exceptional solvent characteristics that make it indispensable in numerous manufacturing processes. The compound's rapid evaporation rate and miscibility with water distinguish it from related solvents such as ethyl acetate and propyl acetate, offering unique advantages in specific applications. From a safety perspective, propan-2-one is classified as a Category 2 flammable liquid under GHS regulations, requiring careful handling and storage protocols. The substance carries GHS02 and GHS07 pictograms with a "Danger" signal word, indicating potential for eye irritation and specific target organ toxicity following single exposure. Its ADR Class 3 classification necessitates compliance with transport regulations for flammable liquids throughout European distribution networks. Industrial applications for propan-2-one span multiple sectors, including pharmaceutical manufacturing where it serves as a critical extraction and purification solvent, paint and coating formulations where its fast evaporation properties enhance application characteristics, and electronics manufacturing for precision cleaning applications. The compound's ability to dissolve both polar and non-polar substances makes it particularly valuable in chemical synthesis processes. OYSI maintains reliable supplies of technical-grade propan-2-one to meet diverse industrial requirements across European markets, ensuring consistent quality and regulatory compliance for our valued customers.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1090
ADR Class3
Packing GroupII
ADR Labels3
Tunnel CodeD/E
Proper Shipping NameACETON
Marine PollutantNo

Frequently Asked Questions

What is propan-2-one?

Propan-2-one is a colorless, volatile organic compound with the molecular formula C3H6O and CAS number 67-64-1. Also known as acetone or dimethyl ketone, it is the simplest ketone with a molecular weight of 58.08 g/mol. This flammable liquid is characterized by its distinctive sweet odor and complete miscibility with water. It serves as one of the most important industrial solvents and chemical intermediates in various manufacturing processes.

What are the physicochemical properties of propan-2-one?

Propan-2-one is a colorless liquid with a characteristic sweet, pungent odor at room temperature. It has a low boiling point of 56°C and is highly volatile, making it readily evaporable. The substance is completely miscible with water and most organic solvents, including alcohols, ethers, and hydrocarbons. Its high volatility and excellent solvent properties, combined with its relatively low toxicity compared to other ketones, make it particularly valuable in industrial applications.

What is propan-2-one used for?

Propan-2-one serves as a versatile industrial solvent for paints, coatings, adhesives, and cleaning products. It is extensively used in the pharmaceutical industry for drug synthesis and purification processes. The chemical industry employs it as an intermediate in producing methyl methacrylate, bisphenol A, and other chemicals. Additionally, it finds applications in nail polish removers, paint thinners, and as a degreasing agent in electronics manufacturing and precision cleaning operations.

How to handle propan-2-one safely?

Propan-2-one requires careful handling due to its flammable nature and potential health effects. Use appropriate personal protective equipment including safety goggles, nitrile gloves, and protective clothing. Ensure adequate ventilation to prevent vapor accumulation and avoid ignition sources such as open flames, hot surfaces, and static electricity. Work in well-ventilated areas or under fume hoods, and have fire extinguishing equipment readily available. Avoid prolonged skin contact and inhalation of vapors.

How to store propan-2-one correctly?

Propan-2-one must be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Use appropriate containers made of compatible materials such as steel or glass, ensuring they are tightly sealed to prevent evaporation. Store separately from strong oxidizing agents, acids, and bases to prevent dangerous reactions. Maintain storage temperatures below 25°C and ensure proper grounding of containers to prevent static electricity buildup during handling.

What to do in case of contact with propan-2-one?

Propan-2-one contact requires immediate action depending on the exposure route. For skin contact, remove contaminated clothing and rinse affected areas with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air and provide oxygen if breathing difficulties occur. For ingestion, do not induce vomiting and seek immediate medical attention while rinsing the mouth with water.

How to dispose of propan-2-one appropriately?

Propan-2-one disposal must comply with local environmental regulations as it is classified as hazardous waste. Small quantities can be recovered through distillation for reuse, while contaminated material requires disposal through licensed hazardous waste contractors. Never dispose of it down drains or into soil, as it can contaminate water sources. Empty containers should be handled as hazardous waste unless properly cleaned and decontaminated according to local regulations and waste management guidelines.

How to transport propan-2-one?

Propan-2-one is classified under ADR as Class 3 (flammable liquid), Packing Group II, requiring specific transport regulations. Containers must meet UN specification standards and display appropriate hazard labels including the flammable liquid pictogram. Transportation vehicles need proper ventilation, grounding equipment, and emergency response information. Drivers must have appropriate training and certification for dangerous goods transport. Quantities exceeding specified limits require additional documentation and safety measures according to European transport regulations.

Is propan-2-one subject to specific regulations?

Propan-2-one is regulated under European REACH and CLP regulations, requiring registration for quantities above one tonne per year. It is classified with hazard statements H225 (highly flammable liquid), H319 (causes serious eye irritation), and H336 (may cause drowsiness). The substance is not listed as a SVHC (Substance of Very High Concern) under REACH. Workplace exposure limits apply in most European countries, and specific safety data sheets must accompany shipments to ensure proper handling and compliance.

Where to buy propan-2-one in Europe?

Propan-2-one is available throughout Europe through OYSI, a specialized chemical distributor offering high-quality industrial chemicals to professional customers. OYSI provides technical-grade and pharmaceutical-grade propan-2-one with complete documentation including safety data sheets, certificates of analysis, and regulatory compliance information. As an established European supplier, OYSI ensures reliable supply chains, proper packaging, and full regulatory compliance for industrial customers across various sectors requiring this versatile solvent and chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.