Propan-2-ol

C3H8O

propan-2-ol

CAS67-63-0
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
67-63-0
EC Number
200-661-7
UN Number
1219
Index Number
603-117-00-0
PubChem CID
3776

Physical-chemical properties

Molecular Formula
C3H8O
Molar Mass
60.10 g/mol
IUPAC Name
propan-2-ol

Chemical Identifiers

InChI
InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
InChI Key
KFZMGEQAYNKOFK-UHFFFAOYSA-N

Overview

Propan-2-ol (CAS 67-63-0) is a secondary alcohol with excellent solvent properties and antimicrobial activity. Also known as isopropyl alcohol or isopropanol, propan-2-ol represents one of the most versatile and widely utilized alcohols in industrial applications. This colorless, flammable liquid with its characteristic odor serves as a critical intermediate in numerous chemical processes and manufacturing operations across Europe. With the molecular formula C3H8O and a molecular weight of 60.1 g/mol, this secondary alcohol exhibits exceptional miscibility with water and most organic solvents, making it invaluable for formulation chemistry. The compound's unique chemical structure provides superior degreasing and cleaning capabilities compared to related solvents like ethyl acetate or propyl acetate, while maintaining relatively low toxicity levels. Its rapid evaporation rate and residue-free drying characteristics have established propan-2-ol as a preferred choice for precision cleaning applications in electronics, pharmaceuticals, and optical industries. From a safety perspective, propan-2-ol is classified as a Category 2 flammable liquid under GHS regulations, requiring appropriate handling precautions and storage conditions. The substance may cause eye irritation and specific target organ toxicity following single exposure, necessitating proper personal protective equipment during industrial use. Primary industrial applications include solvent extraction processes, surface preparation and cleaning, pharmaceutical intermediate synthesis, and as a carrier solvent in coating formulations. The chemical industry extensively utilizes propan-2-ol for producing acetone, various esters, and specialty chemicals. Additionally, its antimicrobial properties make it essential for sanitization processes in pharmaceutical and food processing facilities. OYSI maintains reliable supplies of technical-grade propan-2-ol to support diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1219
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameIsopropanol
Marine PollutantNo

Frequently Asked Questions

What is propan-2-ol?

Propan-2-ol is a secondary alcohol with the molecular formula C3H8O and CAS number 67-63-0. Also known as isopropanol or isopropyl alcohol, it has a molecular weight of 60.1 g/mol. This flammable liquid is classified as dangerous under GHS regulations with hazard classes including Flam. Liq. 2, STOT SE 3, and Eye Irrit. 2, requiring careful handling and storage procedures.

What are the physicochemical properties of propan-2-ol?

Propan-2-ol is a colorless, volatile liquid with a characteristic alcohol odor at room temperature. It is highly miscible with water and most organic solvents, making it an excellent solvent for various applications. The substance has a boiling point of 82.3°C and a flash point of 11.7°C, contributing to its flammable nature and classification as Flam. Liq. 2.

What is propan-2-ol used for?

Propan-2-ol is widely used as a solvent in pharmaceutical, cosmetic, and electronic industries. It serves as a cleaning agent for precision instruments, a disinfectant in healthcare applications, and an intermediate in chemical synthesis. The substance is also employed in the production of acetone, paint thinners, and various industrial cleaning formulations due to its excellent solvency properties.

How to handle propan-2-ol safely?

Propan-2-ol requires careful handling due to its flammable nature and potential health effects. Use appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and ensure adequate ventilation. Avoid ignition sources, as it carries the danger signal word and GHS02 (flame) pictogram. Prevent eye contact due to its Eye Irrit. 2 classification and potential STOT SE 3 effects.

How to store propan-2-ol correctly?

Propan-2-ol must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points due to its Flam. Liq. 2 classification. Use original containers or compatible storage vessels, ensuring proper labeling with GHS02 and GHS07 pictograms. Keep containers tightly closed and store away from incompatible materials such as strong oxidizers and acids.

What to do in case of contact with propan-2-ol?

Propan-2-ol contact requires immediate action due to its Eye Irrit. 2 classification. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately due to potential STOT SE 3 effects. Remove contaminated clothing and seek medical advice if symptoms persist.

How to dispose of propan-2-ol properly?

Propan-2-ol disposal must comply with local and European waste regulations as it is classified as hazardous waste. The substance cannot be disposed of in regular drains due to its flammable nature (Class 3, Group II). Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be allowed for recovery or incineration at authorized facilities following regulatory guidelines.

How to transport propan-2-ol?

Propan-2-ol is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations. Vehicles must carry appropriate hazard placards and documentation. Use UN-approved packaging and ensure drivers have ADR certification. Transport quantities may be subject to tunnel restrictions and specific routing requirements under European dangerous goods transport regulations.

Is propan-2-ol subject to specific regulations?

Propan-2-ol is regulated under European CLP regulation requiring GHS labeling with danger signal word and pictograms GHS02 and GHS07. It falls under REACH registration requirements for manufacturers and importers. The substance is not classified as SVHC (Substance of Very High Concern), but its flammable and irritating properties require compliance with workplace safety directives and chemical safety assessments.

Where to buy propan-2-ol in Europe?

Propan-2-ol is available through OYSI, a European distributor of technical chemicals, ensuring reliable supply across European markets. OYSI provides proper documentation, safety data sheets, and regulatory compliance support for this dangerous substance. As a specialized chemical distributor, OYSI can supply various grades and quantities while ensuring proper packaging and transport according to ADR Class 3 requirements.

Digital Product Passport available

EU DPP

A Digital Product Passport (DPP) compliant with EU regulations is available for this substance. The passport contains complete information on composition, safety, and sustainability.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.