1-phenylpyrazolidin-3-one

1-phenylpyrazolidin-3-one is an organic chemical compound with the molecular formula C9H10N2O and CAS number 92-43-3. This heterocyclic compound features a pyrazolidinone ring structure with a phenyl substituent, giving it a molecular weight of 162.19 g/mol. It belongs to the pyrazolidinone family of compounds and is classified as moderately hazardous with acute toxicity and aquatic chronic toxicity properties.

1-phenylpyrazolidin-3-one is a solid organic compound at room temperature with a molecular weight of 162.19 g/mol. The compound contains nitrogen and oxygen heteroatoms within its five-membered ring structure, which influences its polarity and solubility characteristics. Its physicochemical properties are typical of substituted pyrazolidinones, making it suitable for various synthetic and industrial applications where controlled reactivity is required.

1-phenylpyrazolidin-3-one serves as an important intermediate in pharmaceutical synthesis and organic chemistry applications. The compound is commonly used in the development of active pharmaceutical ingredients and as a building block for more complex molecular structures. Its pyrazolidinone core makes it valuable in medicinal chemistry research, particularly for developing compounds with biological activity. Industrial applications may include specialty chemical synthesis and research purposes.

1-phenylpyrazolidin-3-one requires careful handling due to its Acute Tox. 4 classification and Warning signal word. Operators must wear appropriate personal protective equipment including gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and ensure proper hygiene practices including thorough handwashing after handling to minimize exposure risks.

1-phenylpyrazolidin-3-one should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. The storage area must be secure and accessible only to trained personnel due to its acute toxicity classification. Keep containers properly labeled and maintain appropriate temperature conditions to preserve chemical stability and prevent degradation or hazardous decomposition.

In case of skin contact with 1-phenylpyrazolidin-3-one, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention while providing safety data sheet information.

1-phenylpyrazolidin-3-one must be disposed of according to local and national hazardous waste regulations due to its acute toxicity and aquatic chronic toxicity properties. The compound requires treatment at licensed hazardous waste facilities and cannot be disposed of in regular waste streams. Contact certified waste disposal companies for proper collection and treatment. Ensure proper documentation and tracking of waste disposal to maintain regulatory compliance.

1-phenylpyrazolidin-3-one is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must use UN-approved packaging and display proper hazard labels and markings. Transportation should only be conducted by qualified carriers familiar with dangerous goods handling and emergency procedures.

1-phenylpyrazolidin-3-one is subject to REACH registration requirements in Europe and CLP classification as Acute Tox. 4 and Aquatic Chronic 2. The compound is not listed as a Substance of Very High Concern (SVHC) but requires safety data sheets and proper hazard communication. Users must comply with occupational safety regulations, environmental protection requirements, and proper classification and labeling according to GHS pictograms GHS07 and GHS09.

1-phenylpyrazolidin-3-one is available through OYSI, a European distributor of specialty chemicals serving the pharmaceutical and chemical industries. OYSI provides reliable supply chains for research institutions, pharmaceutical companies, and industrial users requiring this compound for synthesis and development projects. As an established European chemical distributor, OYSI ensures proper regulatory compliance, documentation, and safe handling throughout the supply chain for professional customers.