1-phenylpyrazolidin-3-one

1-phenylpyrazolidin-3-one is an organic compound with the molecular formula C9H10N2O and CAS number 92-43-3. It belongs to the pyrazolidinone family, featuring a five-membered heterocyclic ring containing two nitrogen atoms and a phenyl group attachment. With a molecular weight of 162.19 g/mol, this compound is classified as a moderately hazardous substance requiring careful handling due to its acute toxicity and environmental impact potential.

1-phenylpyrazolidin-3-one is a solid organic compound at room temperature with a molecular weight of 162.19 g/mol. The compound contains a phenyl ring attached to a pyrazolidinone core, giving it specific chemical reactivity patterns. Its exact physical properties such as melting point, boiling point, and solubility characteristics depend on specific grade and purity. The compound's structure makes it moderately polar due to the carbonyl and nitrogen functionalities.

1-phenylpyrazolidin-3-one is primarily used as an intermediate in pharmaceutical synthesis and chemical manufacturing. It serves as a building block for developing various drug compounds and active pharmaceutical ingredients. The compound is also utilized in research and development applications within the chemical industry. Its pyrazolidinone structure makes it valuable for creating derivatives with specific biological or chemical properties in specialized manufacturing processes.

1-phenylpyrazolidin-3-one requires careful handling due to its Acute Tox. 4 classification. Use appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation in work areas to prevent inhalation exposure. Avoid direct skin and eye contact, and do not ingest. Work in a well-ventilated area or under fume hood when possible. Keep emergency eyewash and safety shower accessible during handling operations.

1-phenylpyrazolidin-3-one should be stored in tightly closed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers properly labeled and segregated from incompatible materials. Store at ambient temperature unless otherwise specified by the manufacturer. Ensure storage areas comply with local regulations for hazardous materials. Regular inspection of containers for damage or leakage is recommended to maintain product integrity and safety.

In case of skin contact with 1-phenylpyrazolidin-3-one, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult safety data sheet for specific first aid measures and contact emergency services if necessary.

1-phenylpyrazolidin-3-one must be disposed of according to local, national, and international waste regulations due to its hazardous classification. Contact licensed waste disposal companies specialized in hazardous chemical waste management. Do not discharge into drains, soil, or water bodies as it has Aquatic Chronic 2 classification. Small quantities may require incineration at authorized facilities. Always consult current safety data sheet and local environmental authorities for specific disposal requirements and procedures.

1-phenylpyrazolidin-3-one is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-approved packaging suitable for Class 9 materials. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers require ADR training certification. Ensure proper shipping papers and emergency response information accompany shipments throughout the transportation process.

1-phenylpyrazolidin-3-one is subject to REACH regulation for chemical registration, evaluation, and authorization within the European Union. The compound must comply with CLP regulation for classification, labeling, and packaging requirements. It is not currently listed as a Substance of Very High Concern (SVHC). Users must follow occupational health and safety regulations, environmental protection laws, and transportation regulations. Always verify current regulatory status as requirements may change over time.

1-phenylpyrazolidin-3-one is available through OYSI, a European distributor specializing in technical chemical products. OYSI provides reliable supply chains across European markets with proper regulatory compliance and quality assurance. As a professional chemical distributor, OYSI ensures appropriate packaging, documentation, and handling procedures for hazardous materials. Contact OYSI directly for availability, specifications, and ordering information tailored to your specific industrial or research requirements.