N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine
C23H27ClNP
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Identification
- CAS Number
- 82857-68-9
- EC Number
- 411-370-1
- UN Number
- 2923
- Index Number
- 015-174-00-3
- PubChem CID
- 21997974
Physical-chemical properties
- Molecular Formula
- C23H27ClNP
- Molar Mass
- 383.90 g/mol
- IUPAC Name
- N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine
Chemical Identifiers
- InChI
- InChI=1S/C23H27ClNP/c1-3-25(4-2)26(24,22-16-10-6-11-17-22,23-18-12-7-13-19-23)20-21-14-8-5-9-15-21/h5-19H,3-4,20H2,1-2H3
- InChI Key
- VVSMKQBEDGDJDV-UHFFFAOYSA-N
Overview
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine (CAS 82857-68-9) is an organophosphorus compound featuring a phosphonium center with chloro and benzyl substituents. This specialized organophosphorus compound belongs to the category of phosphonium derivatives, characterized by its unique molecular structure containing both phosphorus and nitrogen functional groups. With a molecular formula of C23H27ClNP and molecular weight of 383.9 g/mol, this chemical exhibits distinctive properties that make it valuable for specific industrial applications requiring phosphorus-containing intermediates. The compound presents significant safety considerations, classified under multiple hazard categories including acute toxicity (Category 3), serious eye damage, and chronic aquatic toxicity. The presence of GHS pictograms GHS06, GHS05, and GHS09 indicates requirements for careful handling protocols, appropriate personal protective equipment, and specialized storage conditions. Its ADR classification as Class 8 confirms its corrosive nature, necessitating compliance with transport regulations for dangerous goods. From a structural perspective, this phosphonium compound shares certain characteristics with other organophosphorus intermediates, though it differs significantly from simpler heterocyclic compounds like 2-chloro-5-(chloromethyl)-1,3-thiazole in terms of molecular complexity and reactivity patterns. The benzyl-chloro-diphenyl substitution pattern around the phosphorus center provides unique electronic and steric properties. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, catalyst precursor in organometallic chemistry, and specialty reagent in advanced organic transformations. The compound's phosphonium structure makes it particularly valuable in processes requiring phase-transfer catalysis or nucleophilic substitution reactions. OYSI maintains reliable supply chains for this specialized organophosphorus compound, supporting European customers with technical documentation and regulatory compliance assistance for safe handling and application.
Safety & Classification
Acute Tox. 3 *; Eye Dam. 1; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2923 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 1-Chlor-N,N-diethyl-1,1-diphenyl-1-(phenylmethyl)phosphoramin |
| Marine Pollutant | No |
Frequently Asked Questions
What is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is an organophosphorus compound with the molecular formula C23H27ClNP and CAS number 82857-68-9. This chemical features a phosphorus center bonded to benzyl, chloro, and diphenyl groups, along with a diethylamino substituent. With a molecular weight of 383.9 g/mol, it belongs to the class of phosphine derivatives and is classified as a hazardous substance requiring careful handling due to its acute toxicity and corrosive properties.
What are the physicochemical properties of N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is an organophosphorus compound with a molecular weight of 383.9 g/mol. The substance contains both hydrophobic aromatic rings and a polar phosphorus-chlorine bond, which influences its solubility characteristics. As a phosphine derivative with multiple aromatic substituents, it likely appears as a solid or viscous liquid at room temperature. The presence of the chloro and phosphanyl groups contributes to its chemical reactivity and potential instability under certain conditions.
What is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine used for?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is primarily used as a specialized reagent in organic synthesis and pharmaceutical research. This organophosphorus compound serves as an intermediate in the preparation of more complex molecules, particularly in the development of phosphine-based catalysts and ligands. Its unique structure makes it valuable for academic research and industrial applications requiring specific phosphorus chemistry transformations. Due to its hazardous nature, its use is typically restricted to professional laboratory settings with appropriate safety measures.
How to handle N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine safely?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine requires strict safety protocols due to its Acute Tox. 3 and Eye Dam. 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles with side shields, and protective clothing covering exposed skin. Work must be conducted in a well-ventilated area or under a fume hood to prevent inhalation. Avoid direct contact with skin, eyes, and clothing. Emergency eyewash stations and safety showers should be readily accessible when handling this corrosive substance.
How to store N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine correctly?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and protect from moisture, as phosphine compounds can be sensitive to hydrolysis. Store separately from oxidizing agents, acids, and bases to prevent dangerous reactions. The storage area should be equipped with appropriate spill containment measures and fire suppression systems. Ensure proper labeling with GHS pictogrammes (GHS06, GHS05, GHS09) and maintain inventory records for regulatory compliance.
What to do in case of contact with N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?
Immediate action is required upon contact with N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine due to its severe eye damage and acute toxicity potential. For eye contact, flush immediately with copious amounts of water for at least 15 minutes and seek urgent medical attention. If skin contact occurs, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of inhalation, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical assistance. Always consult the safety data sheet for specific emergency procedures.
How to dispose of N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine appropriately?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine must be disposed of as hazardous waste through licensed waste management companies. This substance cannot be disposed of in regular waste streams due to its acute toxicity and environmental hazard classification (Aquatic Chronic 2). Collect waste in appropriate containers, properly labeled with contents and hazard information. Contact certified chemical waste disposal services that can handle organophosphorus compounds. Ensure compliance with local, national, and European waste regulations including the Waste Framework Directive.
How to transport N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is classified under ADR Class 8 (Corrosive substances), Packing Group III for transportation. Proper shipping containers must meet UN specification requirements and display appropriate hazard labels including the corrosive substance placard. Transport documentation must include the correct shipping name, UN number, and emergency response information. Drivers must hold ADR certification for Class 8 materials. Ensure vehicles are equipped with appropriate spill containment materials and emergency contact information during transit throughout European routes.
Is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine subject to specific regulations?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is regulated under multiple European frameworks including REACH registration requirements and CLP classification obligations. The substance displays mandatory GHS pictogrammes (GHS06, GHS05, GHS09) and carries the signal word 'Danger' due to its hazardous properties. While not currently identified as a SVHC (Substance of Very High Concern), it requires safety data sheets and proper hazard communication. Import, handling, and use must comply with national chemical safety regulations and workplace exposure limits where established.
Where to buy N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine in Europe?
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is available through OYSI, a specialized European distributor of technical chemicals and research compounds. OYSI provides this organophosphorus compound to qualified customers including research institutions, pharmaceutical companies, and chemical manufacturers across Europe. Due to the hazardous nature of this substance, purchases require proper documentation and compliance with safety regulations. Contact OYSI's technical team for availability, packaging options, and regulatory support to ensure safe handling and transport within European markets.
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ADR Consulting for N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.