N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine

C23H27ClNP

CAS82857-68-9
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
82857-68-9
EC Number
411-370-1
UN Number
2923
Index Number
015-174-00-3
PubChem CID
21997974

Physical-chemical properties

Molecular Formula
C23H27ClNP
Molar Mass
383.90 g/mol
IUPAC Name
N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine

Chemical Identifiers

InChI
InChI=1S/C23H27ClNP/c1-3-25(4-2)26(24,22-16-10-6-11-17-22,23-18-12-7-13-19-23)20-21-14-8-5-9-15-21/h5-19H,3-4,20H2,1-2H3
InChI Key
VVSMKQBEDGDJDV-UHFFFAOYSA-N

Overview

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine (CAS 82857-68-9) is an organophosphorus compound featuring a pentacoordinate phosphorus center with chloride and benzyl substituents. This specialized phosphorus-containing compound represents an important class of organophosphorus chemicals widely utilized in industrial applications. With the molecular formula C23H27ClNP and a molecular weight of 383.9 g/mol, this substance exhibits unique structural characteristics due to its lambda5-phosphanyl configuration, where the phosphorus atom adopts a pentacoordinate geometry. The presence of both benzyl and diphenyl groups attached to the phosphorus center, along with the chloride substituent, provides distinctive chemical reactivity patterns that make it valuable for specific synthetic applications. The compound requires careful handling due to its classification under multiple hazard categories. It presents acute toxicity concerns (Acute Tox. 3), can cause serious eye damage (Eye Dam. 1), and poses chronic aquatic toxicity risks (Aquatic Chronic 2). The associated GHS pictograms include the skull and crossbones (GHS06), corrosion symbol (GHS05), and environmental hazard symbol (GHS09), reflecting its potential risks to human health and the environment. Its ADR classification as Class 8 indicates corrosive properties during transportation. Industrial applications typically involve its use as an intermediate in pharmaceutical synthesis, specialty catalyst systems, and advanced material production. The compound's unique phosphorus chemistry makes it particularly valuable in processes requiring selective reactivity, similar to applications involving other specialized intermediates like 2-chloro-5-(chloromethyl)-1,3-thiazole in heterocyclic synthesis. OYSI maintains strategic inventory of this technical-grade organophosphorus compound to support European industrial customers requiring reliable access to specialized chemical intermediates.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Eye Dam. 1; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H301

Toxic if swallowed.

H318

Causes serious eye damage.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2923
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping Name1-Chlor-N,N-diethyl-1,1-diphenyl-1-(phenylmethyl)phosphoramin
Marine PollutantNo

Frequently Asked Questions

What is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is an organophosphorus compound with the molecular formula C23H27ClNP and CAS number 82857-68-9. This chemical has a molecular weight of 383.9 g/mol and features a complex structure containing benzyl, chloro, diphenyl, and diethylamine groups attached to a phosphorus center. It is classified as a hazardous substance with acute toxicity, eye damage, and aquatic toxicity properties.

What are the physicochemical properties of N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is an organic compound with a molecular weight of 383.9 g/mol and molecular formula C23H27ClNP. As an organophosphorus compound containing aromatic rings and aliphatic chains, it likely exists as a solid or viscous liquid at room temperature. The presence of both hydrophobic aromatic groups and polar phosphorus-nitrogen bonds suggests limited water solubility but good solubility in organic solvents.

What is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine used for?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is primarily used as a specialized chemical intermediate in pharmaceutical and fine chemical synthesis. Its organophosphorus structure makes it valuable as a reagent in organic synthesis, particularly in reactions involving phosphorus chemistry. The compound may also serve as a precursor for the preparation of other phosphorus-containing compounds used in research and development applications within the chemical industry.

How to handle N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine safely?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine requires careful handling due to its acute toxicity and corrosive properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shield, and appropriate respiratory protection. Work should be conducted in a well-ventilated area or fume hood. Avoid skin and eye contact, and prevent inhalation of vapors or dust. Use appropriate tools to minimize direct contact and ensure emergency procedures are readily available.

How to store N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine correctly?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use tightly sealed, chemically compatible containers to prevent contamination and moisture absorption. The storage area should be equipped with appropriate spill containment measures and restricted to authorized personnel only. Keep away from incompatible materials such as strong oxidizers, acids, and bases to prevent dangerous reactions.

What to do in case of contact with N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?

Immediate action is required following contact with N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine due to its toxic and corrosive nature. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention urgently. If inhaled, move to fresh air immediately. Seek immediate medical attention for all exposures.

How to dispose of N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine appropriately?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine must be disposed of as hazardous waste through authorized waste management companies. The compound cannot be disposed of via regular waste streams due to its toxicity and environmental hazard classification. Disposal must comply with local, national, and EU waste regulations. Contact licensed hazardous waste disposal services and provide complete safety data sheets. Ensure proper packaging and labeling according to ADR transport requirements for waste shipment.

How to transport N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is classified under ADR Class 8 (Corrosive substances), Packing Group III for transportation purposes. The compound must be packaged in UN-approved containers suitable for corrosive materials and properly labeled with appropriate hazard markings. Transport documentation must include proper shipping names, UN numbers, and hazard classifications. Only authorized carriers experienced in handling corrosive chemicals should transport this substance, following all ADR regulatory requirements.

Is N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine subject to particular regulations?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is subject to REACH regulation requiring registration for manufacture or import above certain tonnage thresholds. The compound is classified under CLP regulation with specific hazard classifications (Acute Tox. 3, Eye Dam. 1, Aquatic Chronic 2) requiring appropriate labeling and safety data sheets. It is not currently listed as a SVHC substance. Users must comply with occupational safety regulations and may need authorization depending on intended use and quantities handled.

Where to buy N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine in Europe?

N-(benzyl-chloro-diphenyl-lambda5-phosphanyl)-N-ethylethanamine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with complete regulatory documentation, safety data sheets, and technical support to ensure compliance with European chemical regulations. As a professional chemical distributor, OYSI ensures proper handling, packaging, and delivery of this hazardous substance to qualified customers across Europe while maintaining the highest safety and quality standards.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.