Methyl 3-oxobutanoate

Methyl 3-oxobutanoate is an organic chemical compound with the molecular formula C5H8O3 and CAS number 105-45-3. This ester has a molecular weight of 116.11 g/mol and belongs to the beta-keto ester family. It is classified as an eye irritant under GHS regulations, requiring appropriate safety precautions during handling. The compound is commonly used as an intermediate in organic synthesis and pharmaceutical applications.

Methyl 3-oxobutanoate is typically a colorless to pale yellow liquid at room temperature with a characteristic fruity odor. The compound has good solubility in organic solvents such as alcohols, ethers, and esters, while showing limited solubility in water. Its beta-keto ester structure makes it relatively stable under normal conditions but susceptible to hydrolysis in strongly acidic or basic environments.

Methyl 3-oxobutanoate serves primarily as a versatile building block in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of various pharmaceuticals, agrochemicals, and fine chemicals. The compound acts as an important intermediate for synthesizing heterocyclic compounds, amino acids derivatives, and other complex organic molecules. Its applications extend to research laboratories for chemical synthesis and development work.

Methyl 3-oxobutanoate should be handled with appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and protective clothing. Since it is classified as Eye Irritant Category 2, avoid contact with eyes and skin. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Ensure emergency eyewash stations and safety showers are readily accessible when working with this substance.

Methyl 3-oxobutanoate should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers away from strong oxidizing agents, strong acids, and strong bases to prevent unwanted reactions. Store at room temperature in original packaging with proper labeling. Ensure storage areas comply with local fire safety regulations and chemical storage requirements.

In case of eye contact with methyl 3-oxobutanoate, immediately flush eyes with plenty of clean water for at least 15 minutes and seek medical attention promptly due to its eye irritant properties. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical advice. Remove contaminated clothing and wash before reuse.

Methyl 3-oxobutanoate must be disposed of according to local, national, and international waste regulations. Contact authorized waste disposal companies for proper handling and treatment. Do not pour down drains or release into the environment. Small quantities may be suitable for incineration at licensed facilities with appropriate emission controls. Always consult safety data sheets and local authorities for specific disposal requirements and approved disposal methods.

Methyl 3-oxobutanoate can be transported following general chemical transportation guidelines, as it does not appear to have specific ADR classification requirements. However, proper packaging in suitable containers with appropriate labeling including GHS pictogram GHS07 and warning signal word is essential. Ensure packages are properly secured during transport and comply with carrier-specific requirements for chemical shipments and local transportation regulations.

Methyl 3-oxobutanoate is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification as Eye Irritant Category 2. It is not classified as a Substance of Very High Concern (SVHC) under REACH. Companies must comply with safety data sheet requirements, proper labeling with GHS pictogram GHS07, and workplace safety regulations when handling this substance professionally.

Methyl 3-oxobutanoate is available through OYSI, a specialized European distributor of technical chemicals serving industrial and professional customers. OYSI provides reliable supply chains across Europe with proper documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, packaging options, and delivery arrangements to meet your specific technical and commercial requirements for this chemical intermediate.