Chloro(difluoro)methane

CHClF2

chloro(difluoro)methane

CAS75-45-6

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Identification

CAS Number
75-45-6
UN Number
1018
PubChem CID
6372

Physical-chemical properties

Molecular Formula
CHClF2
Molar Mass
86.47 g/mol
IUPAC Name
chloro(difluoro)methane

Chemical Identifiers

InChI
InChI=1S/CHClF2/c2-1(3)4/h1H
InChI Key
VOPWNXZWBYDODV-UHFFFAOYSA-N

Overview

Chloro(difluoro)methane (CAS 75-45-6) is a halogenated hydrocarbon compound with refrigerant and propellant properties commonly known as HCFC-22. This colorless gas belongs to the hydrochlorofluorocarbon (HCFC) family and serves as a critical intermediate in various industrial processes. With its molecular formula CHClF2 and molecular weight of 86.47 g/mol, chloro(difluoro)methane exhibits excellent thermodynamic properties that make it valuable in multiple applications. The compound is classified under ADR Class 2, indicating its status as a compressed gas requiring specific handling and transportation protocols. As a refrigerant gas, chloro(difluoro)methane demonstrates superior heat transfer characteristics and chemical stability under operating conditions. The substance shows minimal toxicity at normal exposure levels, though proper ventilation and safety measures remain essential during handling. Unlike simpler halogenated compounds such as bromane or iodane, this fluorinated derivative offers enhanced thermal stability and reduced reactivity, making it suitable for demanding industrial environments. The primary industrial applications include refrigeration systems, air conditioning units, and as a chemical intermediate in fluoropolymer production. The compound also serves as an effective propellant in aerosol applications and as a blowing agent in foam manufacturing processes. Its controlled vapor pressure and non-flammable nature under normal conditions contribute to its widespread adoption in temperature-controlled applications. In pharmaceutical and specialty chemical synthesis, chloro(difluoro)methane functions as a valuable building block for creating more complex fluorinated organic compounds. The substance requires careful inventory management due to environmental regulations governing HCFC compounds. OYSI maintains reliable supply chains for chloro(difluoro)methane, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number1018
ADR Class2
Packing Group
Tunnel CodeC/E
Proper Shipping NameChlordifluormethan, unter Druck verflüssigt
Marine PollutantNo

Frequently Asked Questions

What is chloro(difluoro)methane?

Chloro(difluoro)methane is a halogenated hydrocarbon with the chemical formula CHClF2 and CAS number 75-45-6. This compound belongs to the family of hydrochlorofluorocarbons (HCFCs) and has a molecular weight of 86.47 g/mol. It contains one chlorine atom and two fluorine atoms bonded to a central carbon atom, making it a versatile chemical intermediate in various industrial processes.

What are the physicochemical properties of chloro(difluoro)methane?

Chloro(difluoro)methane is a colorless gas at room temperature with low toxicity characteristics. As an HCFC compound, it exhibits good chemical stability and has relatively low flammability compared to hydrocarbons. The substance has moderate solubility in organic solvents and limited water solubility. Its boiling point and vapor pressure make it suitable for applications requiring controlled volatility and phase transitions.

What is chloro(difluoro)methane used for?

Chloro(difluoro)methane serves primarily as a refrigerant in cooling systems and as a chemical intermediate in pharmaceutical and agrochemical synthesis. It is used in specialized industrial applications where controlled cooling properties are required. The compound also functions as a solvent in certain chemical processes and as a blowing agent in foam manufacturing. Its applications are increasingly regulated due to environmental considerations.

How to handle chloro(difluoro)methane safely?

Chloro(difluoro)methane should be handled in well-ventilated areas with appropriate personal protective equipment including safety glasses and chemical-resistant gloves. Personnel should avoid prolonged inhalation and ensure adequate ventilation systems are in place. Gas detection equipment is recommended when working with significant quantities. Emergency procedures should be established, and workers should be trained on proper handling techniques and emergency response protocols.

How to store chloro(difluoro)methane correctly?

Chloro(difluoro)methane must be stored in appropriate pressure vessels designed for compressed gases, kept in cool, dry, well-ventilated areas away from heat sources and ignition points. Storage areas should be equipped with gas detection systems and emergency ventilation. The substance should be kept away from incompatible materials and stored according to local regulations for compressed gases and refrigerants.

What to do in case of contact with chloro(difluoro)methane?

In case of inhalation of chloro(difluoro)methane, immediately move the affected person to fresh air and seek medical attention if breathing difficulties occur. For skin contact, remove contaminated clothing and flush the affected area with water. Eye contact requires immediate irrigation with clean water for at least 15 minutes. If large quantities are released, evacuate the area and ensure proper ventilation before re-entry.

How to dispose of chloro(difluoro)methane appropriately?

Chloro(difluoro)methane must be disposed of through licensed waste management facilities specialized in handling refrigerants and halogenated compounds. Recovery and recycling systems are preferred to minimize environmental impact. The substance should never be released directly to the atmosphere due to its ozone depletion potential. Disposal must comply with local environmental regulations and international protocols governing HCFC substances.

How to transport chloro(difluoro)methane?

Chloro(difluoro)methane is classified under ADR Class 2 (gases) for transportation purposes. It must be transported in approved pressure vessels and containers meeting international transportation standards. Vehicles must carry appropriate hazard placards and emergency response information. Drivers require specialized training for transporting compressed gases, and emergency equipment must be available during transport operations.

Is chloro(difluoro)methane subject to specific regulations?

Chloro(difluoro)methane is subject to various environmental regulations including the Montreal Protocol due to its ozone depletion potential. Under European REACH regulation, it requires registration for commercial use. The substance is also regulated under F-gas legislation controlling the use and handling of fluorinated greenhouse gases. Users must comply with reporting requirements and phase-out schedules established by environmental authorities.

Where to buy chloro(difluoro)methane in Europe?

Chloro(difluoro)methane is available through OYSI, a European distributor of technical chemicals serving industrial customers across the continent. OYSI provides reliable supply chains and technical support for customers requiring this specialized chemical. As a regulated substance, purchases typically require verification of intended use and compliance with applicable environmental regulations. Contact OYSI for availability and regulatory compliance assistance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.