Benzenesulfonohydrazide

Benzenesulfonohydrazide is an organic chemical compound with the molecular formula C6H8N2O2S and CAS number 80-17-1. This sulfonamide derivative features a benzene ring connected to a sulfonyl group bonded to a hydrazide moiety. With a molecular weight of 172.21 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. The compound exhibits relatively low toxicity profile with no specific hazard classifications under current regulatory frameworks.

Benzenesulfonohydrazide appears as a white to off-white crystalline solid at room temperature. The compound demonstrates good thermal stability under normal conditions and exhibits moderate solubility in polar solvents like water and alcohols, while showing limited solubility in non-polar organic solvents. Its melting point typically ranges between 100-110°C, and it remains stable under ambient storage conditions when protected from moisture and extreme temperatures.

Benzenesulfonohydrazide serves primarily as a chemical intermediate in pharmaceutical synthesis and organic chemistry applications. It functions as a building block for developing sulfonamide-based drugs, antimicrobial agents, and other bioactive compounds. The compound is also utilized in research laboratories for synthetic organic chemistry studies and as a reagent in various chemical transformations involving hydrazide chemistry and sulfonyl group modifications.

Benzenesulfonohydrazide should be handled using standard laboratory safety practices including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. While the compound shows no specific hazard classifications, avoid direct skin and eye contact, and prevent ingestion. Use proper handling techniques for powdered materials to minimize dust generation during transfer operations.

Benzenesulfonohydrazide should be stored in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. Maintain storage temperatures below 25°C and protect from moisture to prevent degradation. Keep containers properly labeled and store away from strong oxidizing agents and acids. Ensure adequate ventilation in storage areas and implement appropriate inventory management practices including regular inspection of container integrity.

In case of skin contact with benzenesulfonohydrazide, immediately wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention. Remove contaminated clothing and wash before reuse.

Benzenesulfonohydrazide waste should be disposed of according to local and national hazardous waste regulations. Contact licensed waste disposal companies for proper collection and treatment. Small laboratory quantities can typically be collected with other organic chemical wastes for incineration at appropriate facilities. Never dispose of the compound through regular trash or drain systems. Maintain proper documentation of waste disposal activities and follow institutional waste management protocols.

Benzenesulfonohydrazide is classified under ADR Class 4.1 as a flammable solid for transportation purposes. Packages must comply with appropriate packing group requirements and bear proper hazard labels during shipment. Use UN-approved packaging materials and ensure containers are properly sealed and labeled with shipping names, UN numbers, and hazard warnings. Follow carrier-specific requirements for documentation and handling during transit operations.

Benzenesulfonohydrazide is regulated under REACH (Registration, Evaluation, Authorization of Chemicals) in the European Union and must comply with registration requirements for commercial use. The compound is not currently listed as a Substance of Very High Concern (SVHC). Standard CLP (Classification, Labelling and Packaging) regulations apply for proper labeling and safety data sheet requirements. Users must ensure compliance with local chemical safety regulations and workplace exposure limits.

Benzenesulfonohydrazide is available through OYSI, a trusted European distributor of specialty chemicals serving industrial and research customers across the continent. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for product availability, technical specifications, and pricing information. The company offers reliable supply chain management and technical support for European customers requiring this specialized chemical intermediate.