6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one

C10H9Cl2NO

CAS118289-55-7
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

Consulting for 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
118289-55-7
EC Number
421-320-0
UN Number
3077
Index Number
606-091-00-9
PubChem CID
10609474

Physical-chemical properties

Molecular Formula
C10H9Cl2NO
Molar Mass
230.09 g/mol
IUPAC Name
6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one

Chemical Identifiers

InChI
InChI=1S/C10H9Cl2NO/c11-2-1-6-3-7-4-10(14)13-9(7)5-8(6)12/h3,5H,1-2,4H2,(H,13,14)
InChI Key
ZTQQXEPZEYIVDK-UHFFFAOYSA-N

Overview

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one (CAS 118289-55-7) is a halogenated indole derivative with significant aquatic toxicity properties requiring careful environmental handling protocols. This specialized organic compound belongs to the indole family, characterized by its bicyclic structure containing a benzene ring fused to a pyrrole ring. The presence of two chlorine atoms - one directly attached to the aromatic ring and another on the ethyl side chain - significantly influences both its chemical reactivity and biological activity. With a molecular formula of C10H9Cl2NO and molecular weight of 230.09 g/mol, this compound exhibits distinct physicochemical properties that make it valuable for specific industrial applications. The compound's classification under GHS09 pictogram with "Warning" signal word reflects its primary environmental hazards, specifically Aquatic Acute 1 and Aquatic Chronic 1 classifications. These designations indicate severe toxicity to aquatic life with long-lasting effects, necessitating stringent handling and disposal protocols. Transportation falls under ADR Class 9 (miscellaneous dangerous substances), requiring appropriate documentation and packaging standards for safe logistics. Industrial applications typically include use as an intermediate in pharmaceutical synthesis, particularly in the development of compounds targeting neurological pathways. The chloroethyl functionality makes it valuable in chemical modification processes and as a building block for more complex molecular structures. Unlike simpler compounds such as copper(1+) thiocyanate, this indole derivative offers specific reactivity patterns essential for advanced synthetic chemistry applications. Research and specialty chemical manufacturing represent primary market segments, where its unique structural features enable the synthesis of bioactive compounds and pharmaceutical intermediates. OYSI provides reliable access to 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one with comprehensive technical support and regulatory documentation for European customers.

Safety & Classification

Warning
Classification:

Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name6-Chlor-5-(2-chlorethyl)-1,3-dihydroindol-2-on
Marine PollutantNo

Frequently Asked Questions

What is 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is an organic chemical compound with the molecular formula C10H9Cl2NO and CAS number 118289-55-7. This chlorinated indolinone derivative has a molecular weight of 230.09 g/mol and contains two chlorine substituents on the indolinone ring system. It is classified as hazardous to aquatic environments and requires careful handling according to safety regulations.

What are the physicochemical properties of 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is a chlorinated organic compound with a molecular weight of 230.09 g/mol and formula C10H9Cl2NO. As a substituted indolinone derivative, it likely exists as a solid at room temperature. The presence of chlorine atoms and the lactam functionality influence its polarity and solubility characteristics. Specific physical properties such as melting point, boiling point, and solubility data would require analytical characterization.

What is 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one used for?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is primarily used as an intermediate in organic synthesis and pharmaceutical research. This chlorinated indolinone derivative serves as a building block for the development of bioactive compounds and drug candidates. Its structural features make it valuable for medicinal chemistry applications, particularly in the synthesis of heterocyclic compounds with potential therapeutic properties. Industrial applications may include specialty chemical manufacturing.

How to handle 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one safely?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one requires careful handling due to its aquatic toxicity classification. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to avoid inhalation. Prevent release to the environment as it poses acute and chronic hazards to aquatic life. Follow standard laboratory safety protocols for handling organic chemicals.

How to store 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one correctly?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Keep containers protected from moisture and light to maintain chemical stability. Store separately from strong oxidizers and bases. Ensure storage areas have appropriate spill containment measures due to its aquatic toxicity. Maintain proper inventory records and labeling.

What to do in case of contact with 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one?

In case of skin contact with 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for several minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures.

How to dispose of 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one appropriately?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one must be disposed of as hazardous waste through licensed waste management companies due to its aquatic toxicity classification. Never discharge to sewers, waterways, or soil as it poses environmental hazards. Collect waste in appropriate containers and label clearly. Follow local and national regulations for hazardous waste disposal. Consider incineration at authorized facilities as a suitable disposal method for organic chlorinated compounds.

How to transport 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation. Use appropriate UN-specification packaging and ensure proper labeling with GHS09 environmental hazard pictogram. Transport documentation must include the correct shipping name and hazard information. Vehicles should carry appropriate emergency equipment and drivers must be trained in hazardous goods transport regulations.

Is 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one subject to specific regulations?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is subject to REACH regulation in Europe and must comply with CLP classification requirements. It carries the warning signal word and GHS09 environmental hazard pictogram due to its aquatic toxicity (Aquatic Acute 1; Aquatic Chronic 1). The substance is not currently listed as SVHC under REACH. Users must follow proper registration, evaluation, and authorization procedures when handling commercial quantities.

Where to buy 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one in Europe?

6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one is available through OYSI, a specialized European distributor of fine and specialty chemicals. OYSI provides high-quality chemical products with proper documentation and regulatory compliance for research and industrial applications. Contact OYSI directly for availability, specifications, and technical support. As a professional chemical distributor, OYSI ensures proper handling, packaging, and delivery according to safety and transport regulations.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.