4-(1H-benzimidazol-2-yl)-1,3-thiazole

4-(1H-benzimidazol-2-yl)-1,3-thiazole is a heterocyclic organic compound combining benzimidazole and thiazole ring systems. With the molecular formula C10H7N3S and CAS number 148-79-8, this compound has a molecular weight of 201.25 g/mol. It belongs to the class of benzimidazole derivatives and is classified as hazardous to aquatic environments, requiring careful handling and environmental precautions during use and disposal.

4-(1H-benzimidazol-2-yl)-1,3-thiazole is a solid compound at room temperature with a molecular weight of 201.25 g/mol. The compound contains nitrogen and sulfur heteroatoms within its fused ring structure, which influences its chemical reactivity and physical properties. As a heterocyclic aromatic compound, it likely exhibits limited water solubility and stability under normal storage conditions. Specific physical properties such as melting point and exact solubility data should be confirmed through technical documentation.

4-(1H-benzimidazol-2-yl)-1,3-thiazole is primarily used as an intermediate in pharmaceutical and chemical synthesis. Its benzimidazole-thiazole structure makes it valuable for developing bioactive compounds, particularly in medicinal chemistry research. The compound may serve as a building block for synthesizing more complex molecules with potential therapeutic applications. It is also used in research applications for studying heterocyclic chemistry and as a reference standard in analytical laboratories.

4-(1H-benzimidazol-2-yl)-1,3-thiazole should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety goggles, gloves, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation. Given its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1), prevent environmental release and ensure proper containment. Follow good laboratory practices, avoid direct skin and eye contact, and wash hands thoroughly after handling.

4-(1H-benzimidazol-2-yl)-1,3-thiazole should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed to prevent moisture absorption and contamination. Store separately from incompatible materials and ensure proper labeling with hazard information. Given its environmental hazards, implement measures to prevent accidental release. Maintain storage temperatures as recommended in the safety data sheet and regularly inspect containers for integrity.

In case of skin contact with 4-(1H-benzimidazol-2-yl)-1,3-thiazole, immediately wash affected areas with plenty of soap and water. For eye contact, rinse thoroughly with clean water for at least 15 minutes and seek medical attention if irritation persists. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Remove contaminated clothing and wash before reuse. Always consult the safety data sheet for specific first aid measures.

4-(1H-benzimidazol-2-yl)-1,3-thiazole must be disposed of as hazardous chemical waste due to its aquatic toxicity classification. Never dispose of this substance down drains, in soil, or with regular waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Follow local and national regulations for chemical waste management. Ensure containers are properly labeled and documented for waste tracking. Prevent environmental contamination during collection, storage, and transport to disposal facilities.

4-(1H-benzimidazol-2-yl)-1,3-thiazole is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. This classification requires specific packaging, labeling, and documentation requirements for road transport within Europe. Packages must bear appropriate hazard labels and proper shipping names. Transport vehicles may need placarding depending on quantities. Ensure compliance with ADR regulations and use approved packaging materials. Consult current transport regulations for specific requirements and exemptions.

4-(1H-benzimidazol-2-yl)-1,3-thiazole is subject to European chemical regulations including REACH and CLP classifications. It is currently not listed as a Substance of Very High Concern (SVHC). The compound carries GHS09 pictogram and 'Warning' signal word due to its aquatic toxicity. Users must comply with safety data sheet requirements, proper labeling, and environmental protection measures. Industrial users may need to fulfill REACH downstream user obligations and implement appropriate risk management measures as specified in exposure scenarios.

4-(1H-benzimidazol-2-yl)-1,3-thiazole is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to research institutions, pharmaceutical companies, and industrial users across Europe. As an established chemical distributor, OYSI ensures proper handling, documentation, and compliance with European regulations. For availability, pricing, and technical specifications, contact OYSI directly through their official channels. They can provide certificates of analysis, safety data sheets, and regulatory compliance documentation required for professional use.