2-[4-[5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]phenyl]sulfonyl-N,N-dimethylethanamine

2-[4-[5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]phenyl]sulfonyl-N,N-dimethylethanamine is an organic chemical compound with the molecular formula C19H22ClN3O2S and CAS number 10357-99-0. This complex molecule contains a pyrazoline ring system with a chlorophenyl substituent and a sulfonyl-linked dimethylaminoethyl group. With a molecular weight of 391.9 g/mol, it belongs to the class of heterocyclic compounds and requires careful handling due to its classification as a skin sensitizer and specific target organ toxicant.

The compound has a molecular weight of 391.9 g/mol and molecular formula C19H22ClN3O2S. As a complex organic molecule containing both polar (sulfonyl, amine) and nonpolar (chlorophenyl) groups, it likely exhibits moderate polarity. The presence of the chlorine atom and aromatic rings suggests limited water solubility, while the dimethylamino group may provide some degree of water miscibility. Specific physical properties such as melting point, boiling point, and exact solubility data would require experimental determination or detailed technical specifications.

This compound is primarily used in pharmaceutical research and development, particularly in the synthesis of bioactive molecules and drug intermediates. Its complex structure containing pyrazoline and sulfonyl functionalities makes it valuable for medicinal chemistry applications. It may serve as a building block for developing compounds with potential therapeutic properties, including anti-inflammatory or antimicrobial activities. The compound is also utilized in academic research for studying structure-activity relationships and in the development of new chemical synthetic methodologies.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Skin Sens. 1 classification. Work should be conducted in a well-ventilated area or under a fume hood to prevent inhalation exposure, as the compound is classified as STOT RE 2. Avoid direct skin contact and ensure proper hygiene practices. Use non-sparking tools and equipment, and maintain clean work surfaces. Always consult the safety data sheet before handling and ensure personnel are trained in proper chemical handling procedures.

Store the compound in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Use tightly sealed, chemically compatible containers to prevent moisture absorption and contamination. Keep away from incompatible materials such as strong oxidizing agents and bases. Maintain storage temperature below 25°C and ensure proper labeling with hazard information. Store in a designated chemical storage area with appropriate fire suppression systems and ensure containers are regularly inspected for damage or leakage. Follow local regulations for chemical storage.

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes due to the skin sensitization risk. For eye contact, rinse immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures and contact emergency services if severe symptoms develop.

Disposal must be conducted according to local and national hazardous waste regulations due to its environmental and health classifications. The compound should be collected in appropriate hazardous waste containers and disposed of through licensed waste management facilities. Do not dispose of in regular trash, down drains, or into the environment due to its Aquatic Chronic 2 classification. Contact certified waste disposal companies for proper collection and treatment. Maintain waste disposal records and ensure compliance with REACH and local environmental protection regulations. Consider waste minimization strategies during use.

The compound is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, indicating it requires special transport considerations. Use appropriate UN-specification packaging and ensure proper labeling with Class 9 hazard labels. Transport vehicles must carry appropriate emergency response information and comply with ADR routing restrictions. Drivers must be trained in hazardous materials transport. Ensure packages are secured to prevent damage during transport and avoid extreme temperatures. Documentation must include proper shipping names, hazard classes, and emergency contact information as required by international transport regulations.

The compound is subject to REACH regulation requirements for registration, evaluation, and authorization in Europe, though it is not currently listed as a Substance of Very High Concern (SVHC). It must comply with CLP regulation for classification, labeling, and packaging as indicated by its GHS08, GHS07, and GHS09 pictograms. Transport is regulated under ADR as Class 9 dangerous goods. Users must maintain safety data sheets, conduct risk assessments, and implement appropriate control measures. Regular monitoring of regulatory updates is recommended as classification requirements may change.

OYSI serves as a reliable European distributor for this specialized chemical compound, offering professional supply chain management and technical support. As an established chemical distributor, OYSI ensures proper handling, storage, and documentation compliance with European regulations. The company provides comprehensive safety data sheets and can assist with regulatory requirements for REACH compliance. Contact OYSI directly for availability, specifications, and pricing information. Their expertise in hazardous materials handling ensures safe delivery and proper documentation for research and industrial applications across European markets.