4-hydroxy-3,5-diiodobenzonitrile

4-hydroxy-3,5-diiodobenzonitrile is an organic compound with the molecular formula C7H3I2NO and CAS number 1689-83-4. This chemical features a benzene ring substituted with a hydroxyl group, two iodine atoms, and a nitrile group. With a molecular weight of 370.91 g/mol, it is classified as a hazardous substance requiring careful handling due to its toxicological properties.

4-hydroxy-3,5-diiodobenzonitrile is typically a solid crystalline compound at room temperature. The presence of two iodine atoms contributes to its relatively high molecular weight of 370.91 g/mol. The compound contains both hydrophilic (hydroxyl and nitrile groups) and lipophilic characteristics. Its solubility profile and exact melting point depend on purity and crystalline form.

4-hydroxy-3,5-diiodobenzonitrile is primarily used as an intermediate in pharmaceutical synthesis and organic chemistry research. The compound serves as a building block for more complex molecules, particularly in the development of iodinated compounds. Its unique substitution pattern makes it valuable for specialized chemical transformations and as a precursor in medicinal chemistry applications.

4-hydroxy-3,5-diiodobenzonitrile requires careful handling due to its classification as Acute Tox. 3-4 and Repr. 2. Essential safety measures include wearing appropriate personal protective equipment (gloves, safety glasses, lab coats), working in well-ventilated areas or fume hoods, and avoiding skin contact and inhalation. The GHS08 and GHS06 pictograms indicate serious health hazards requiring strict safety protocols.

4-hydroxy-3,5-diiodobenzonitrile should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled according to CLP regulations. Due to its hazardous classification, storage areas should be restricted to authorized personnel only. Maintain appropriate temperature conditions and protect from light if specified by the manufacturer.

Immediate action is required in case of contact with 4-hydroxy-3,5-diiodobenzonitrile due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact (Eye Irrit. 2), flush immediately with clean water for at least 15 minutes. If inhaled or ingested, seek immediate medical attention and provide the safety data sheet to medical personnel.

4-hydroxy-3,5-diiodobenzonitrile disposal must comply with local and European waste regulations due to its hazardous classification. The compound cannot be disposed of as regular waste and requires specialized hazardous waste treatment. Contact licensed waste disposal companies for proper handling. The aquatic toxicity classification necessitates preventing environmental release. Maintain disposal records as required by regulations.

4-hydroxy-3,5-diiodobenzonitrile is classified under ADR Class 6.1 (Toxic substances), Packing Group II, indicating significant transport restrictions. Professional dangerous goods transportation is required with appropriate packaging, labeling, and documentation. Drivers must have ADR certification, and vehicles must carry emergency equipment. Shipments require proper dangerous goods declarations and emergency response information.

4-hydroxy-3,5-diiodobenzonitrile is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as SVHC, its reproductive toxicity (Repr. 2) classification triggers specific handling and communication requirements. Users must comply with occupational exposure limits and may need authorization depending on application and quantities used.

4-hydroxy-3,5-diiodobenzonitrile is available through OYSI, a specialized European distributor of chemical products. OYSI provides this compound with full regulatory compliance including safety data sheets and proper hazardous goods documentation. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transportation according to ADR Class 6.1 requirements for toxic substances.