4-hydroxy-3,5-diiodobenzonitrile

4-hydroxy-3,5-diiodobenzonitrile is an organic compound with the molecular formula C7H3I2NO and CAS number 1689-83-4. This chemical features a benzene ring substituted with a hydroxyl group, two iodine atoms, and a nitrile group. With a molecular weight of 370.91 g/mol, it is classified as a hazardous substance with multiple danger classifications including reproductive toxicity and acute toxicity.

4-hydroxy-3,5-diiodobenzonitrile is typically a solid crystalline compound at room temperature due to its aromatic structure and halogen substituents. The presence of two iodine atoms significantly increases its molecular weight and density. The hydroxyl and nitrile groups influence its polarity and solubility characteristics. Its exact physical properties like melting point and solubility depend on purity and specific conditions.

4-hydroxy-3,5-diiodobenzonitrile is primarily used as an intermediate in pharmaceutical synthesis and organic chemistry research. Its unique structure with iodine substituents makes it valuable for medicinal chemistry applications, particularly in the development of bioactive compounds. It may also serve as a building block in the synthesis of more complex organic molecules and potentially in materials science applications requiring iodinated aromatic compounds.

4-hydroxy-3,5-diiodobenzonitrile requires careful handling due to its multiple hazard classifications including acute toxicity and reproductive toxicity. Essential protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Emergency washing facilities should be readily accessible during handling operations.

4-hydroxy-3,5-diiodobenzonitrile should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Given its hazardous classification, storage areas should be secure and properly labeled with appropriate hazard warnings. Keep away from heat sources, direct sunlight, and moisture. Storage should comply with local regulations for toxic substances and include appropriate containment measures for spill prevention.

Immediate action is required upon contact with 4-hydroxy-3,5-diiodobenzonitrile due to its toxicity profile. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention, providing the safety data sheet to medical personnel.

4-hydroxy-3,5-diiodobenzonitrile must be disposed of as hazardous waste through licensed waste disposal companies due to its toxic properties and environmental hazard classification. Never dispose of this substance through regular waste streams or sewage systems. Contact certified hazardous waste disposal services and provide complete chemical identification. Disposal must comply with local, national, and European waste regulations, particularly those governing toxic and environmentally hazardous substances.

4-hydroxy-3,5-diiodobenzonitrile is classified under ADR Class 6.1 (Toxic substances) with Packing Group II, indicating significant transport restrictions. Transportation requires appropriate UN-specification packaging, proper labeling with GHS pictograms (GHS06, GHS08, GHS09), and accompanying transport documentation. Only authorized carriers experienced in handling toxic materials should transport this substance, following all ADR regulations for dangerous goods throughout Europe.

4-hydroxy-3,5-diiodobenzonitrile is subject to comprehensive European chemical regulations under REACH and CLP frameworks. Its classification as Repr. 2 and multiple acute toxicity categories requires strict compliance with hazard communication and safety requirements. While not currently listed as SVHC, its hazardous properties mean it falls under various worker protection and environmental regulations. Users must maintain safety data sheets and comply with occupational exposure limits where established.

4-hydroxy-3,5-diiodobenzonitrile is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this compound with appropriate documentation including safety data sheets and certificates of analysis. Given the substance's hazardous classification, purchases typically require verification of legitimate use and proper handling capabilities. Contact OYSI directly for availability, specifications, and regulatory compliance support.