4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is an organic compound with the molecular formula C19H16O3 and CAS number 5836-29-3. This chromen-2-one derivative has a molecular weight of 292.3 g/mol and features a complex structure combining a chromone core with a tetrahydronaphthalene substituent. It is classified as a highly hazardous substance with multiple toxicity concerns including reproductive toxicity, acute toxicity, and environmental hazards.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is a solid organic compound with a molecular weight of 292.3 g/mol. The compound contains hydroxyl and ketone functional groups, suggesting moderate polarity. Its chromone structure typically exhibits limited water solubility but better solubility in organic solvents. The presence of aromatic rings and the hydroxyl group may contribute to its stability under normal conditions, though specific physical data should be confirmed through technical documentation.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is primarily used in specialized chemical research and pharmaceutical intermediate applications. Its chromone structure makes it valuable in medicinal chemistry research and as a building block for more complex molecules. Due to its high toxicity classification (Repr. 1B, Acute Tox. 2-3), its use is restricted to professional applications with appropriate safety measures and regulatory compliance.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one requires extreme caution due to its Danger classification and multiple hazard classes. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume extraction. Avoid skin contact, inhalation, and ingestion. Implement strict hygiene measures including thorough hand washing and contaminated clothing removal before leaving work areas.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one must be stored in a secure, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed, chemically compatible containers and maintain cool, dry conditions. Due to its high toxicity and reproductive hazard classification, implement restricted access controls and proper labeling. Store away from oxidizing agents and ensure compliance with local regulations for highly hazardous substances. Regular inventory checks and leak inspections are essential.

Immediate action is required for any contact with 4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one due to its high acute toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes. Seek immediate medical attention in all cases, providing the safety data sheet to medical personnel. Never induce vomiting if ingested.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one must be disposed of as hazardous waste through licensed waste management companies. Due to its multiple hazard classifications including environmental toxicity (Aquatic Chronic 1), it cannot be disposed of in regular waste streams or released to the environment. Containerize waste in compatible packaging, label appropriately, and maintain waste tracking documentation. Consult local environmental authorities for specific disposal requirements and approved disposal facilities.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating high toxicity requiring the most stringent transport controls. Shipments must use UN-approved packaging, proper labeling with toxic substance markings, and appropriate transport documentation. Only authorized carriers experienced in hazardous materials transport should handle shipments. Vehicle placarding and driver certification requirements apply according to ADR regulations.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. While not currently listed as a SVHC, its Repr. 1B classification may trigger additional restrictions. Companies must maintain safety data sheets, implement risk management measures, and ensure worker protection compliance. Import/export may require permits, and workplace exposure limits must be observed where established by national authorities.

4-hydroxy-3-(1,2,3,4-tetrahydronaphthalen-1-yl)chromen-2-one is available through specialized chemical distributors like OYSI, a European distributor of technical chemicals. Due to its high hazard classification, procurement is limited to qualified professional users with appropriate handling capabilities and regulatory compliance. Suppliers must provide comprehensive documentation including safety data sheets, certificates of analysis, and transport classification. Contact OYSI directly for availability, technical specifications, and regulatory support for this controlled substance.