3H-1,3-benzothiazole-2-thione

3H-1,3-benzothiazole-2-thione is an organosulfur compound with the molecular formula C7H5NS2 and CAS number 149-30-4. This heterocyclic compound contains both nitrogen and sulfur atoms within its benzothiazole ring structure, with an additional thione group. With a molecular weight of 167.3 g/mol, it appears as a crystalline solid and is classified as a skin sensitizer with environmental hazard properties. It requires careful handling due to its potential allergenic effects and aquatic toxicity.

3H-1,3-benzothiazole-2-thione is a solid crystalline compound at room temperature, typically appearing as yellow to pale yellow crystals or powder. The compound has a molecular weight of 167.3 g/mol and contains sulfur, which may contribute to a characteristic odor. It shows limited solubility in water but is generally soluble in organic solvents. The presence of the thione group and the aromatic benzothiazole ring system contributes to its stability and chemical reactivity patterns.

3H-1,3-benzothiazole-2-thione is primarily used as an intermediate in organic synthesis and pharmaceutical applications. It serves as a building block for the synthesis of various benzothiazole derivatives, which are important in medicinal chemistry and agrochemical production. The compound is also utilized in rubber vulcanization processes as an accelerator and in the production of specialty chemicals. Its unique chemical structure makes it valuable for developing compounds with biological activity and industrial applications.

3H-1,3-benzothiazole-2-thione requires careful handling due to its skin sensitization properties (Skin Sens. 1). Always wear appropriate personal protective equipment including nitrile gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume extraction to avoid inhalation. Avoid generating dust and prevent environmental release due to its aquatic toxicity. Follow GHS07 and GHS09 pictogram warnings and ensure proper training before handling this substance.

3H-1,3-benzothiazole-2-thione should be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from oxidizing agents and strong acids or bases. Due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), ensure secondary containment to prevent environmental release. Maintain storage temperatures as recommended by the supplier and ensure proper labeling according to CLP requirements.

In case of skin contact with 3H-1,3-benzothiazole-2-thione, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if symptoms persist. Due to its skin sensitization properties, monitor for allergic reactions and consult a physician if sensitization symptoms develop. Always have safety data sheet available for emergency responders.

3H-1,3-benzothiazole-2-thione must be disposed of as hazardous waste through licensed waste management companies due to its environmental hazard classification. Never discharge into drains, soil, or water bodies as it is highly toxic to aquatic life (Aquatic Acute 1, Aquatic Chronic 1). Collect waste in appropriate containers, properly labeled with waste identification codes. Follow local and European waste regulations including the Waste Framework Directive. Consider waste minimization through process optimization and explore recycling options where technically feasible.

3H-1,3-benzothiazole-2-thione is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. This classification requires appropriate UN-specification packaging and proper shipping documentation including dangerous goods declarations. Vehicles must carry appropriate placards and emergency response information. Drivers require ADR training certification for Class 9 materials. Ensure packages are properly marked with UN numbers, proper shipping names, and hazard labels. Follow ADR regulations for loading, segregation, and transport conditions to ensure safe delivery.

3H-1,3-benzothiazole-2-thione is subject to European REACH regulation requiring registration for manufacture or import above 1 tonne per year. It must be classified and labeled according to CLP Regulation as Skin Sens. 1, Aquatic Acute 1, and Aquatic Chronic 1 with Warning signal word and GHS07/GHS09 pictograms. While not currently listed as SVHC, its environmental and health hazard properties require compliance with occupational exposure limits and environmental protection measures. Regular safety data sheet updates and exposure assessments may be required under REACH.

3H-1,3-benzothiazole-2-thione is available through OYSI, a trusted European distributor of specialty chemicals with extensive experience in handling hazardous materials. OYSI provides comprehensive technical support, regulatory compliance documentation, and reliable supply chain management across Europe. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transport according to ADR Class 9 requirements. Contact OYSI directly for pricing, availability, technical specifications, and safety data sheets to meet your specific application requirements while ensuring full regulatory compliance.