3H-1,3-benzothiazole-2-thione

3H-1,3-benzothiazole-2-thione is an organosulfur compound with the molecular formula C7H5NS2 and CAS number 149-30-4. This heterocyclic compound contains both nitrogen and sulfur atoms within its benzothiazole ring structure. With a molecular weight of 167.3 g/mol, it is classified as a skin sensitizer and poses environmental hazards to aquatic life, requiring careful handling in industrial applications.

3H-1,3-benzothiazole-2-thione typically appears as a crystalline solid at room temperature with a characteristic sulfur-containing compound odor. The molecule contains both aromatic benzene and thiazole ring systems, contributing to its stability and chemical reactivity. Its solubility varies depending on the solvent, with polar aprotic solvents generally providing better dissolution than water due to its organic heterocyclic structure.

3H-1,3-benzothiazole-2-thione serves as an important intermediate in pharmaceutical synthesis and chemical manufacturing processes. It is commonly used in the production of various benzothiazole derivatives and as a building block for more complex organic molecules. The compound also finds applications in research laboratories for synthetic chemistry studies and in the development of specialized chemical products requiring sulfur-nitrogen heterocyclic structures.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume hoods to avoid inhalation exposure, as the compound is classified as a skin sensitizer (Skin Sens. 1). Avoid direct contact with skin and eyes, and ensure proper hygiene practices including thorough handwashing after handling.

Store 3H-1,3-benzothiazole-2-thione in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers properly labeled and segregated from incompatible materials, particularly strong oxidizing agents. Maintain storage areas with appropriate temperature control and ensure containers are made of compatible materials to prevent degradation or contamination of the product.

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. Seek medical attention if irritation persists or if sensitization symptoms develop, as this compound is classified as a skin sensitizer.

Disposal must comply with local, national, and international environmental regulations due to its aquatic toxicity classification (Aquatic Acute 1; Aquatic Chronic 1). Contact licensed waste disposal companies specialized in hazardous chemical waste management. Never dispose of this substance through regular drainage systems or municipal waste streams. Ensure proper documentation and tracking of waste disposal according to applicable environmental protection laws.

3H-1,3-benzothiazole-2-thione is classified under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. Use appropriate packaging that meets UN specification requirements for this classification. Ensure proper labeling with hazard pictogrammes GHS07 and GHS09, and include necessary transport documentation. Follow ADR regulations for loading, segregation, and vehicle requirements when shipping this material.

3H-1,3-benzothiazole-2-thione falls under REACH regulation for chemical registration and evaluation within the European Union. It is classified under CLP regulation with specific hazard pictogrammes (GHS07, GHS09) and warning signal word. The substance is not currently listed as SVHC (Substance of Very High Concern), but its skin sensitization and aquatic toxicity properties require compliance with relevant safety and environmental protection regulations.

3H-1,3-benzothiazole-2-thione is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance for industrial and research applications. Contact OYSI directly for availability, technical specifications, packaging options, and delivery throughout Europe while ensuring all regulatory requirements are met.