3,4-dichloroaniline

3,4-dichloroaniline is an aromatic amine compound with the molecular formula C6H5Cl2N and CAS number 95-76-1. This chlorinated aniline derivative has a molecular weight of 162.01 g/mol and contains two chlorine atoms positioned at the 3 and 4 positions on the benzene ring relative to the amino group. It is classified as a hazardous substance with multiple toxicity concerns and environmental risks, requiring careful handling and regulatory compliance in industrial applications.

3,4-dichloroaniline is typically a crystalline solid at room temperature with a characteristic aromatic amine odor. As a chlorinated aromatic compound, it exhibits limited water solubility but dissolves readily in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The presence of two chlorine substituents affects its melting point, boiling point, and chemical reactivity compared to unsubstituted aniline. Its aromatic structure makes it relatively stable under normal conditions but susceptible to oxidation and further chemical modifications.

3,4-dichloroaniline serves primarily as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is commonly used in the production of azo dyes and other colorants for textile and industrial applications. The compound also functions as a building block in pharmaceutical synthesis and agrochemical manufacturing. Its chlorinated structure makes it valuable for creating more complex molecules through various chemical reactions, particularly in specialty chemical production where specific substitution patterns are required.

3,4-dichloroaniline requires strict safety measures due to its Acute Tox. 3, Eye Dam. 1, and Skin Sens. 1 classifications. Workers must wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Adequate ventilation is essential to minimize inhalation exposure. Handle in designated areas with emergency washing facilities readily available. Avoid generating dust or vapors, and never eat, drink, or smoke in work areas. Train all personnel on proper handling procedures before use.

3,4-dichloroaniline must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from strong oxidizers, acids, and bases that could react with the amine group. Maintain storage temperature below 25°C and protect from direct sunlight. Use secondary containment to prevent environmental release. Ensure storage areas have appropriate fire suppression systems and emergency spill response equipment readily available.

3,4-dichloroaniline exposure requires immediate action due to its acute toxicity and eye damage potential. For skin contact, immediately remove contaminated clothing and wash affected area with plenty of soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for at least 15 minutes and seek immediate medical attention due to the Eye Dam. 1 classification. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention immediately. Always consult a physician after any exposure incident.

3,4-dichloroaniline disposal must comply with local and national hazardous waste regulations due to its toxicity and environmental hazard classifications. The compound cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies for proper collection and treatment. Incineration at high temperatures in approved facilities is typically the preferred disposal method. Empty containers may also require special handling as hazardous waste. Maintain proper documentation for all disposal activities as required by regulations.

3,4-dichloroaniline is classified under ADR Class 6.1 (toxic substances), Packing Group II, requiring strict transport regulations compliance. Packages must bear appropriate hazard labels including GHS06, GHS05, and GHS09 pictograms with 'Danger' signal word. Use UN-approved packaging designed for Class 6.1 materials. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers require ADR training certification. Ensure proper segregation from incompatible materials during transport and maintain temperature control to prevent degradation or hazardous reactions.

3,4-dichloroaniline is subject to comprehensive chemical safety regulations including REACH registration requirements in Europe and CLP classification as Acute Tox. 3, Eye Dam. 1, Skin Sens. 1, and Aquatic hazard categories. While not currently listed as an SVHC, it requires safety data sheets, hazard communication, and worker protection measures. Industrial users must implement risk management measures and may need authorization for certain uses. Transportation follows ADR Class 6.1 requirements, and waste disposal is regulated under hazardous waste legislation.

3,4-dichloroaniline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this regulated substance to qualified industrial customers with proper documentation and regulatory compliance support. As a controlled chemical requiring specialized handling, 3,4-dichloroaniline is typically sold only to established businesses with appropriate safety infrastructure and regulatory permissions. Contact OYSI's technical team for availability, specifications, and regulatory guidance to ensure compliant procurement and use of this hazardous chemical substance.