2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one
C7H9NOS
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Identification
- CAS Number
- 82633-79-2
- EC Number
- 407-630-9
- UN Number
- 2811
- Index Number
- 613-185-00-3
- PubChem CID
- 158190
Physical-chemical properties
- Molecular Formula
- C7H9NOS
- Molar Mass
- 155.22 g/mol
- IUPAC Name
- 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one
Chemical Identifiers
- InChI
- InChI=1S/C7H9NOS/c1-8-7(9)5-3-2-4-6(5)10-8/h2-4H2,1H3
- InChI Key
- PZOGAKOZVSTZSO-UHFFFAOYSA-N
Overview
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one (CAS 82633-79-2) is a heterocyclic organic compound with thiazole functionality and cyclopentane ring structure. This specialized chemical compound represents a unique class of fused ring systems combining thiazole and cyclopentane moieties. With its molecular formula C7H9NOS and molecular weight of 155.22 g/mol, this substance exhibits distinctive structural properties that make it valuable for specific industrial applications. The compound features a bicyclic framework where the thiazole ring is fused with a saturated cyclopentane ring, creating a rigid molecular architecture that influences its chemical reactivity and biological activity. The safety profile of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one requires careful handling protocols due to its classification under multiple hazard categories. It presents acute toxicity concerns (Acute Tox. 3), can cause serious eye damage (Eye Dam. 1), and may trigger allergic skin reactions (Skin Sens. 1). Additionally, the compound poses environmental risks with acute and chronic aquatic toxicity classifications. The ADR transport classification of 6.1 indicates its status as a toxic substance requiring specialized shipping procedures. Industrial applications typically leverage the compound's heterocyclic structure for pharmaceutical intermediates and specialty chemical synthesis. The thiazole moiety provides opportunities for further chemical modifications, making it useful in drug discovery programs and materials science research. Unlike structurally different compounds such as 2,2-dibromo-2-cyanoacetamide, which serves primarily as a biocide, this thiazole derivative offers unique synthetic pathways for complex molecule construction. OYSI maintains reliable supplies of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one with comprehensive technical support and regulatory documentation for European distribution.
Safety & Classification
Acute Tox. 3 *; Eye Dam. 1; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 2,3,5,6-Tetrahydro-2-methyl-2H-cyclopenta[d]-1,2-thiazol-3-on |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is a heterocyclic organic compound with the molecular formula C7H9NOS and CAS number 82633-79-2. This thiazole derivative has a molecular weight of 155.22 g/mol and features a fused ring system combining a cyclopentane and thiazole moiety. It is classified as a hazardous substance with acute toxicity properties and requires careful handling in industrial applications.
What are the physicochemical properties of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is a compound with molecular formula C7H9NOS and molecular weight 155.22 g/mol. As a thiazole derivative containing sulfur, nitrogen, and oxygen atoms in its heterocyclic structure, it likely exists as a solid at room temperature. The presence of the carbonyl group and nitrogen atom suggests potential for hydrogen bonding, which may influence its solubility characteristics in polar solvents.
What is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one used for?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is typically used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its heterocyclic structure makes it valuable as a building block for developing bioactive compounds and specialty chemicals. The thiazole moiety is commonly found in various pharmaceutical applications, making this compound useful in medicinal chemistry research and drug development processes within controlled industrial environments.
How to handle 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one safely?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one requires careful handling due to its Acute Tox. 3, Eye Dam. 1, and Skin Sens. 1 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin and eye contact, and ensure emergency eyewash stations are readily accessible during handling operations.
How to store 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one correctly?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Due to its hazardous classification, store in designated chemical storage areas with appropriate secondary containment. Keep away from heat sources, direct sunlight, and moisture. Ensure storage areas have proper ventilation and access restrictions to trained personnel only, following local chemical storage regulations.
What to do in case of contact with 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?
Immediate action is required due to the substance's Eye Dam. 1 and Skin Sens. 1 classifications. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention while providing safety data sheet information.
How to dispose of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one properly?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one must be disposed of as hazardous chemical waste due to its toxicity and environmental hazard classifications. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into drains, soil, or waterways due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Follow local and European waste regulations, including proper waste coding and documentation for traceability.
How to transport 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires appropriate UN-specification packaging, proper labeling with Class 6.1 hazard labels, and accompanying transport documentation. Drivers must hold ADR certification for Class 6.1 materials. Ensure packages are properly sealed, labeled, and segregated according to dangerous goods regulations during transport across European borders.
Is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one subject to specific regulations?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is subject to European REACH and CLP regulations due to its hazardous properties but is not classified as a Substance of Very High Concern (SVHC). The substance must be properly classified, labeled, and supplied with safety data sheets. Companies handling quantities above REACH thresholds must ensure proper registration. Transport requires compliance with ADR regulations for Class 6.1 toxic substances, including proper packaging and documentation.
Where to buy 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one in Europe?
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance for European markets. As a professional chemical distributor, OYSI ensures appropriate packaging, handling, and delivery logistics for hazardous materials while maintaining quality standards required for research and industrial applications.
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2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.