2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one

C7H9NOS

CAS82633-79-2
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

Consulting for 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one

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Identification

CAS Number
82633-79-2
EC Number
407-630-9
UN Number
2811
Index Number
613-185-00-3
PubChem CID
158190

Physical-chemical properties

Molecular Formula
C7H9NOS
Molar Mass
155.22 g/mol
IUPAC Name
2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one

Chemical Identifiers

InChI
InChI=1S/C7H9NOS/c1-8-7(9)5-3-2-4-6(5)10-8/h2-4H2,1H3
InChI Key
PZOGAKOZVSTZSO-UHFFFAOYSA-N

Overview

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one (CAS 82633-79-2) is a heterocyclic organic compound with thiazole functionality and cyclopentane ring structure. This specialized chemical compound represents a unique class of fused ring systems combining thiazole and cyclopentane moieties. With its molecular formula C7H9NOS and molecular weight of 155.22 g/mol, this substance exhibits distinctive structural properties that make it valuable for specific industrial applications. The compound features a bicyclic framework where the thiazole ring is fused with a saturated cyclopentane ring, creating a rigid molecular architecture that influences its chemical reactivity and biological activity. The safety profile of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one requires careful handling protocols due to its classification under multiple hazard categories. It presents acute toxicity concerns (Acute Tox. 3), can cause serious eye damage (Eye Dam. 1), and may trigger allergic skin reactions (Skin Sens. 1). Additionally, the compound poses environmental risks with acute and chronic aquatic toxicity classifications. The ADR transport classification of 6.1 indicates its status as a toxic substance requiring specialized shipping procedures. Industrial applications typically leverage the compound's heterocyclic structure for pharmaceutical intermediates and specialty chemical synthesis. The thiazole moiety provides opportunities for further chemical modifications, making it useful in drug discovery programs and materials science research. Unlike structurally different compounds such as 2,2-dibromo-2-cyanoacetamide, which serves primarily as a biocide, this thiazole derivative offers unique synthetic pathways for complex molecule construction. OYSI maintains reliable supplies of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one with comprehensive technical support and regulatory documentation for European distribution.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Eye Dam. 1; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H301

Toxic if swallowed.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name2,3,5,6-Tetrahydro-2-methyl-2H-cyclopenta[d]-1,2-thiazol-3-on
Marine PollutantNo

Frequently Asked Questions

What is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is a heterocyclic organic compound with the molecular formula C7H9NOS and CAS number 82633-79-2. This thiazole derivative has a molecular weight of 155.22 g/mol and features a fused ring system combining a cyclopentane and thiazole moiety. It is classified as a hazardous substance with acute toxicity properties and requires careful handling in industrial applications.

What are the physicochemical properties of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is a compound with molecular formula C7H9NOS and molecular weight 155.22 g/mol. As a thiazole derivative containing sulfur, nitrogen, and oxygen atoms in its heterocyclic structure, it likely exists as a solid at room temperature. The presence of the carbonyl group and nitrogen atom suggests potential for hydrogen bonding, which may influence its solubility characteristics in polar solvents.

What is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one used for?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is typically used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its heterocyclic structure makes it valuable as a building block for developing bioactive compounds and specialty chemicals. The thiazole moiety is commonly found in various pharmaceutical applications, making this compound useful in medicinal chemistry research and drug development processes within controlled industrial environments.

How to handle 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one safely?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one requires careful handling due to its Acute Tox. 3, Eye Dam. 1, and Skin Sens. 1 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin and eye contact, and ensure emergency eyewash stations are readily accessible during handling operations.

How to store 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one correctly?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Due to its hazardous classification, store in designated chemical storage areas with appropriate secondary containment. Keep away from heat sources, direct sunlight, and moisture. Ensure storage areas have proper ventilation and access restrictions to trained personnel only, following local chemical storage regulations.

What to do in case of contact with 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?

Immediate action is required due to the substance's Eye Dam. 1 and Skin Sens. 1 classifications. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention while providing safety data sheet information.

How to dispose of 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one properly?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one must be disposed of as hazardous chemical waste due to its toxicity and environmental hazard classifications. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into drains, soil, or waterways due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Follow local and European waste regulations, including proper waste coding and documentation for traceability.

How to transport 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires appropriate UN-specification packaging, proper labeling with Class 6.1 hazard labels, and accompanying transport documentation. Drivers must hold ADR certification for Class 6.1 materials. Ensure packages are properly sealed, labeled, and segregated according to dangerous goods regulations during transport across European borders.

Is 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one subject to specific regulations?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is subject to European REACH and CLP regulations due to its hazardous properties but is not classified as a Substance of Very High Concern (SVHC). The substance must be properly classified, labeled, and supplied with safety data sheets. Companies handling quantities above REACH thresholds must ensure proper registration. Transport requires compliance with ADR regulations for Class 6.1 toxic substances, including proper packaging and documentation.

Where to buy 2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one in Europe?

2-methyl-5,6-dihydro-4H-cyclopenta[d][1,2]thiazol-3-one is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance for European markets. As a professional chemical distributor, OYSI ensures appropriate packaging, handling, and delivery logistics for hazardous materials while maintaining quality standards required for research and industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.