3-(methylaminomethyl)aniline

C8H12N2

CAS18759-96-1
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
18759-96-1
EC Number
414-570-7
UN Number
2923
Index Number
612-193-00-4
PubChem CID
11643936

Physical-chemical properties

Molecular Formula
C8H12N2
Molar Mass
136.19 g/mol
IUPAC Name
3-(methylaminomethyl)aniline

Chemical Identifiers

InChI
InChI=1S/C8H12N2/c1-10-6-7-3-2-4-8(9)5-7/h2-5,10H,6,9H2,1H3
InChI Key
HBLPYXIZPMDWIO-UHFFFAOYSA-N

Overview

3-(methylaminomethyl)aniline (CAS 18759-96-1) is an aromatic amine compound with dual amine functionalities providing versatile chemical reactivity and intermediate capabilities. This organic compound belongs to the substituted aniline family, featuring both a primary aromatic amine group and a secondary aliphatic amine group within its molecular structure. With a molecular formula of C8H12N2 and molecular weight of 136.19 g/mol, this chemical intermediate exhibits characteristic properties of aromatic amines while offering enhanced reactivity due to its methylaminomethyl substituent. The compound's bifunctional nature makes it particularly valuable in synthetic chemistry applications where multiple reactive sites are advantageous. From a safety perspective, 3-(methylaminomethyl)aniline requires careful handling due to its hazardous properties. The substance is classified with multiple danger categories including acute toxicity, skin corrosion (1B), and skin sensitization potential. Environmental precautions are essential as it presents acute and chronic aquatic toxicity. The compound falls under ADR transport class 8, indicating its corrosive nature, and displays GHS pictograms for health hazards, corrosion, and environmental dangers. Industrial applications typically focus on its role as a chemical intermediate in pharmaceutical synthesis, specialty polymer production, and fine chemical manufacturing. The compound's dual amine functionality enables its use in crosslinking applications and as a building block for more complex molecular structures. Unlike simpler compounds such as N-cyclohexylcyclohexanamine, this aromatic derivative offers additional conjugation and specific positioning of reactive groups that prove valuable in targeted synthetic pathways. OYSI supplies 3-(methylaminomethyl)aniline to meet the demanding requirements of European chemical manufacturers and research institutions.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2923
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping Name3-Methylaminomethylphenylamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline is an aromatic organic compound with the molecular formula C8H12N2 and CAS number 18759-96-1. This chemical belongs to the aniline family and features both primary and secondary amine functional groups. With a molecular weight of 136.19 g/mol, it is classified as a hazardous substance requiring careful handling due to its corrosive and toxic properties.

What are the physicochemical properties of 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline is an organic compound with molecular formula C8H12N2 and molecular weight 136.19 g/mol. As an aromatic amine derivative, it typically appears as a liquid or crystalline solid at room temperature. The compound contains both aromatic and aliphatic amine functionalities, making it reactive toward acids and electrophiles. Its physicochemical behavior is influenced by the presence of two nitrogen atoms capable of hydrogen bonding.

What is 3-(methylaminomethyl)aniline used for?

3-(methylaminomethyl)aniline serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. The compound is primarily used in the production of specialized chemicals, dyes, and pharmaceutical intermediates. Its dual amine functionality makes it valuable for creating complex molecular structures through various chemical reactions. It may also find applications in the development of polymers and specialty materials requiring specific nitrogen-containing building blocks.

How to handle 3-(methylaminomethyl)aniline safely?

3-(methylaminomethyl)aniline requires strict safety measures due to its Skin Corr. 1B and Acute Tox. 4 classifications. Always wear chemical-resistant gloves, safety goggles, and protective clothing when handling. Work in well-ventilated areas or under fume hoods to avoid inhalation exposure. The substance can cause severe skin burns and is harmful if swallowed or inhaled, requiring immediate safety protocols and proper training before use.

How to store 3-(methylaminomethyl)aniline correctly?

3-(methylaminomethyl)aniline must be stored in tightly sealed, chemically compatible containers away from heat, light, and moisture. Keep the substance in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers and acids. Due to its corrosive nature (Skin Corr. 1B), use appropriate containment measures and ensure storage areas are equipped with spill control materials and emergency equipment.

What to do in case of contact with 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline contact requires immediate emergency response due to its corrosive properties. For skin contact, immediately remove contaminated clothing and flush with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care.

How to dispose of 3-(methylaminomethyl)aniline appropriately?

3-(methylaminomethyl)aniline disposal must comply with local and European waste regulations due to its hazardous classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies for proper handling and destruction. All contaminated materials, including containers and protective equipment, must be treated as hazardous waste and disposed of accordingly through authorized channels.

How to transport 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline is classified as ADR Class 8 (corrosive substances), Packing Group II, requiring specialized transport procedures. The substance must be packaged in UN-approved containers suitable for corrosive materials and properly labeled with appropriate hazard markings. Transport vehicles must comply with ADR regulations, and drivers require hazardous materials certification. Proper shipping documentation and emergency response information must accompany all shipments.

Is 3-(methylaminomethyl)aniline subject to specific regulations?

3-(methylaminomethyl)aniline is subject to European REACH and CLP regulations due to its hazardous properties. The substance is not currently listed as an SVHC (Substance of Very High Concern), but its Acute Tox. 4, Skin Corr. 1B, and aquatic toxicity classifications require compliance with safety data sheet requirements, classification and labeling obligations, and potential registration under REACH depending on tonnage and use patterns.

Where to buy 3-(methylaminomethyl)aniline in Europe?

3-(methylaminomethyl)aniline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance, including proper classification, safety documentation, and transport arrangements according to ADR requirements. As experienced chemical distributors, OYSI ensures quality standards and regulatory compliance for professional users requiring this specialized aromatic amine compound for their applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.