3-(methylaminomethyl)aniline

C8H12N2

CAS18759-96-1
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
18759-96-1
EC Number
414-570-7
UN Number
2923
Index Number
612-193-00-4
PubChem CID
11643936

Physical-chemical properties

Molecular Formula
C8H12N2
Molar Mass
136.19 g/mol
IUPAC Name
3-(methylaminomethyl)aniline

Chemical Identifiers

InChI
InChI=1S/C8H12N2/c1-10-6-7-3-2-4-8(9)5-7/h2-5,10H,6,9H2,1H3
InChI Key
HBLPYXIZPMDWIO-UHFFFAOYSA-N

Overview

3-(methylaminomethyl)aniline (CAS 18759-96-1) is an aromatic diamine compound featuring both primary aniline and secondary methylamine functional groups. This versatile chemical intermediate belongs to the family of substituted anilines, characterized by its unique dual amine functionality that makes it valuable for various synthetic applications. With the molecular formula C8H12N2 and a molecular weight of 136.19 g/mol, this compound exhibits the typical reactivity patterns associated with both aromatic primary amines and aliphatic secondary amines. The presence of these complementary functional groups enables diverse chemical transformations and coupling reactions. From a safety perspective, 3-(methylaminomethyl)aniline requires careful handling due to its corrosive nature and potential health hazards. Classified under multiple acute toxicity categories and as a skin corrosive substance (Skin Corr. 1B), it demands appropriate personal protective equipment and controlled storage conditions. The compound also presents environmental concerns, being classified as acutely and chronically toxic to aquatic life, necessitating proper waste management protocols. Its ADR classification as Class 8 reflects its corrosive transport requirements. Industrial applications typically focus on its role as a chemical intermediate in pharmaceutical synthesis, polymer chemistry, and specialty chemical manufacturing. The compound's dual amine functionality makes it particularly useful for crosslinking reactions and as a building block for complex molecular architectures. Like other amine-containing compounds such as N-cyclohexylcyclohexanamine, it can serve in applications requiring controlled reactivity and specific structural features. OYSI maintains reliable supply chains for this specialized chemical intermediate, ensuring consistent availability for European industrial customers requiring high-quality aromatic amine compounds.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2923
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping Name3-Methylaminomethylphenylamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline is an organic chemical compound with the molecular formula C8H12N2 and CAS number 18759-96-1. This aromatic amine derivative contains both aniline and methylamine functional groups, giving it a molecular weight of 136.19 g/mol. It is classified as a hazardous substance with corrosive properties and acute toxicity, requiring careful handling in industrial applications.

What are the physicochemical properties of 3-(methylaminomethyl)aniline?

3-(methylaminomethyl)aniline is an organic compound with molecular formula C8H12N2 and molecular weight 136.19 g/mol. As an aromatic amine derivative, it typically exists as a liquid or solid at room temperature. The presence of both aniline and methylamine functional groups influences its solubility characteristics and chemical reactivity, making it suitable for various synthetic applications.

What is 3-(methylaminomethyl)aniline used for?

3-(methylaminomethyl)aniline serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. This compound is primarily used in the production of specialized chemicals, dyes, and potentially active pharmaceutical ingredients due to its dual amine functionality. Its unique structure makes it valuable for creating complex molecular frameworks in fine chemical synthesis and research applications.

How to handle 3-(methylaminomethyl)aniline safely?

Safe handling of 3-(methylaminomethyl)aniline requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Skin Corr. 1B classification. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact as the substance can cause severe burns and allergic reactions.

How to store 3-(methylaminomethyl)aniline correctly?

3-(methylaminomethyl)aniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. As a corrosive substance, it requires storage in appropriate chemical-resistant containers and secondary containment systems. Keep away from heat sources, oxidizing agents, and ensure proper labeling with GHS pictograms GHS05, GHS07, and GHS09.

What to do in case of contact with 3-(methylaminomethyl)aniline?

Immediate action is required in case of contact with 3-(methylaminomethyl)aniline due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. Seek immediate medical attention for any exposure. In case of eye contact, rinse thoroughly with water and get prompt medical care.

How to dispose of 3-(methylaminomethyl)aniline appropriately?

Disposal of 3-(methylaminomethyl)aniline must comply with local and national hazardous waste regulations due to its classification as corrosive and aquatically toxic. The substance should be collected and treated by licensed waste management companies specializing in hazardous chemical disposal. Never dispose of this material in regular waste streams or discharge into water systems.

How to transport 3-(methylaminomethyl)aniline?

Transportation of 3-(methylaminomethyl)aniline is regulated under ADR Class 8 (corrosive substances), Packing Group II, indicating moderate danger level. The substance requires appropriate hazardous goods packaging, labeling, and documentation during transport. Only certified carriers experienced in handling corrosive chemicals should transport this material, following all applicable dangerous goods regulations.

Is 3-(methylaminomethyl)aniline subject to specific regulations?

3-(methylaminomethyl)aniline is subject to various chemical safety regulations including CLP classification requirements and REACH registration obligations in Europe. The substance is not currently listed as an SVHC (Substance of Very High Concern). Companies must comply with safety data sheet requirements, proper labeling with danger signal word, and appropriate risk management measures.

Where to buy 3-(methylaminomethyl)aniline in Europe?

3-(methylaminomethyl)aniline is available through OYSI, a specialized European distributor of technical chemicals and intermediates. As an established chemical supplier, OYSI can provide this compound with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.