3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one;hydrochloride

3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one;hydrochloride is a synthetic organic compound with the molecular formula C11H16Cl2N2O and CAS number 93076-03-0. This heterocyclic compound features a pyridopyrimidinone core structure with a chloroethyl substituent and exists as a hydrochloride salt. With a molecular weight of 263.16 g/mol, it is classified as a hazardous substance requiring careful handling due to its toxicological properties.

The compound is a solid crystalline material at room temperature due to its hydrochloride salt form. As a chlorinated heterocyclic compound with both polar and nonpolar regions, it likely exhibits moderate solubility in polar solvents such as water and alcohols. The presence of the hydrochloride salt enhances water solubility compared to the free base. Specific physical parameters such as melting point, density, and exact solubility data would require analytical determination.

This compound is primarily used in pharmaceutical research and development as an intermediate or building block in organic synthesis. Its unique pyridopyrimidinone structure makes it valuable for medicinal chemistry applications, particularly in the development of bioactive molecules. The chloroethyl functionality provides a reactive site for further chemical modifications. It may also serve as a reference standard in analytical laboratories or as a starting material for the synthesis of more complex pharmaceutical compounds.

Safe handling requires comprehensive personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 3, Eye Dam. 1, and Skin Sens. 1 classifications. Work must be conducted in a well-ventilated area or under fume hood to prevent inhalation exposure. Avoid direct skin and eye contact, and prevent dust formation. Use appropriate engineering controls and ensure emergency eyewash and shower facilities are readily accessible.

The compound should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Store in a designated chemical storage area with appropriate secondary containment. Given its hazard classification, ensure storage complies with local regulations for toxic substances and maintain proper inventory records. Segregate from food, feed, and potable water supplies.

Immediate action is critical due to the Eye Dam. 1 classification. For eye contact, rinse immediately with copious amounts of water for at least 15 minutes and seek medical attention urgently. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for complete first aid procedures.

Disposal must comply with local, national, and EU waste regulations as this compound is classified as hazardous waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge to sewers, waterways, or soil due to its Aquatic Chronic 2 classification. Incineration at authorized high-temperature facilities may be appropriate. Maintain waste manifests and disposal documentation as required by regulations. Empty containers may also require special disposal procedures.

Transportation is regulated under ADR Class 6.1 (toxic substances), Packing Group III. Packages must bear appropriate UN identification numbers, proper shipping names, and hazard labels including the toxic symbol. Use UN-specification packaging suitable for Class 6.1 materials. Transport documents must include emergency response information and contact details. Drivers require ADR training certification, and vehicles must carry appropriate safety equipment. Segregation rules apply to prevent incompatible cargo mixing.

The compound is subject to EU REACH regulation requiring registration for manufacture or import above one tonne annually. CLP classification mandates specific labeling with GHS pictograms (GHS06, GHS08, GHS05, GHS09) and 'Danger' signal word. It is not currently listed as a SVHC under REACH. Transport regulations under ADR apply for shipments. Additional restrictions may apply under national chemical control laws or for specific uses such as biocides or pharmaceuticals.

OYSI serves as a reliable European distributor for this specialized chemical compound, offering comprehensive supply chain solutions across Europe. As an established chemical distributor, OYSI provides quality assurance, regulatory compliance support, and technical expertise for pharmaceutical intermediates and research chemicals. Contact OYSI directly for availability, specifications, and delivery options. Our European network ensures efficient logistics and regulatory compliance for hazardous materials transport and handling requirements.