(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile is an organic compound with the molecular formula C14H11NO2 and CAS number 61826-76-4. This chiral molecule features a phenoxyphenyl group attached to a hydroxyacetonitrile moiety, with a molecular weight of 225.24 g/mol. It is classified as a hazardous substance requiring careful handling due to its acute toxicity, eye damage potential, and environmental concerns.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile is a solid organic compound at room temperature with a molecular weight of 225.24 g/mol. The compound contains both aromatic and aliphatic functional groups, including a nitrile group, a hydroxyl group, and a phenoxy linkage. Its solubility characteristics and specific physical properties depend on the solvent system used, with the polar hydroxyl and nitrile groups influencing its behavior in various media.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile serves as an important intermediate in pharmaceutical and fine chemical synthesis. Its chiral nature makes it valuable for asymmetric synthesis applications and as a building block for more complex molecules. The compound is primarily used in research and development laboratories, pharmaceutical manufacturing, and specialty chemical production where stereoselective synthesis is required.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile requires careful handling due to its Acute Tox. 3, Eye Dam. 1, and Skin Sens. 1 classifications. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods, avoid skin and eye contact, and ensure emergency eyewash stations are accessible. Handle with appropriate tools to minimize direct contact.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled with hazard information. Store separately from strong oxidizing agents and bases. Ensure storage areas have appropriate secondary containment and are accessible only to trained personnel with proper safety equipment.

In case of eye contact with (2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile, immediately flush with plenty of water for at least 15 minutes and seek immediate medical attention due to its Eye Dam. 1 classification. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air. Remove contaminated clothing. In all cases of exposure, seek medical advice promptly and provide the safety data sheet to medical personnel.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile must be disposed of as hazardous waste according to local and national regulations. Due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications, prevent environmental release. Contact licensed waste disposal companies for proper treatment and disposal. Do not discharge to sewers, waterways, or soil. Maintain disposal records and ensure compliance with all applicable environmental regulations and waste codes.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile is classified under ADR Class 6.1 (Toxic substances), Packing Group III. Transportation requires appropriate UN-specification packaging, proper labeling with GHS pictogrammes (GHS06, GHS05, GHS09), and accompanying transport documents. Vehicles must carry appropriate emergency equipment and drivers need ADR training. Ensure packages are secured to prevent damage during transport and follow all dangerous goods transportation regulations.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile is subject to REACH regulation in Europe and requires CLP classification and labeling due to its hazardous properties. While not currently listed as SVHC, it must be handled according to its danger classification with appropriate risk management measures. Users must comply with occupational safety regulations, environmental protection laws, and maintain safety data sheets. Registration and notification requirements may apply depending on quantities handled.

(2S)-2-hydroxy-2-(3-phenoxyphenyl)acetonitrile is available through OYSI, a trusted European distributor of specialty chemicals and pharmaceutical intermediates. OYSI provides proper documentation including safety data sheets, certificates of analysis, and regulatory compliance information. As an established chemical distributor, OYSI ensures quality products with appropriate packaging and labeling for safe handling and transportation throughout Europe.