2-sulfanylacetic acid

C2H4O2S

CAS68-11-1
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
68-11-1
EC Number
200-677-4
UN Number
1940
Index Number
607-090-00-6
PubChem CID
1133

Physical-chemical properties

Molecular Formula
C2H4O2S
Molar Mass
92.12 g/mol
IUPAC Name
2-sulfanylacetic acid

Chemical Identifiers

InChI
InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
InChI Key
CWERGRDVMFNCDR-UHFFFAOYSA-N

Overview

2-sulfanylacetic acid (CAS 68-11-1) is an organosulfur compound with strong reducing properties and characteristic thiol functionality. This important industrial chemical, also known by its molecular formula C2H4O2S, represents a unique combination of carboxylic acid and thiol functional groups within a single molecule. With a molecular weight of 92.12 g/mol, 2-sulfanylacetic acid serves as a versatile building block in various chemical processes and manufacturing applications across multiple industries. The compound exhibits significant safety considerations due to its corrosive nature and acute toxicity profile. Classified under GHS pictograms GHS06 and GHS05, it carries a "Danger" signal word and falls under Skin Corr. 1B and Acute Tox. 3 categories. Transportation regulations classify it as ADR Class 8, reflecting its corrosive properties. The presence of both sulfur and carboxyl groups contributes to its reactivity profile, distinguishing it from simpler organosulfur compounds and other corrosive materials like tribromoborane in terms of its specific chemical behavior. Industrial applications of 2-sulfanylacetic acid include its use as a reducing agent in pharmaceutical synthesis, where its thiol group provides valuable reducing capabilities. The compound also finds application in metal processing and surface treatment operations, where its dual functionality proves advantageous. Additionally, it serves as an intermediate in the production of various specialty chemicals and biochemical research applications. The unique structural characteristics of this organosulfur acid, combining carboxylic acid stability with thiol reactivity, make it particularly valuable in controlled chemical processes requiring selective reduction or specific sulfur chemistry applications. OYSI maintains availability of 2-sulfanylacetic acid to support European industrial customers' technical chemical requirements.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1940
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping NameThioglycolsäure
Marine PollutantNo

Frequently Asked Questions

What is 2-sulfanylacetic acid?

2-sulfanylacetic acid is an organosulfur compound with the molecular formula C2H4O2S and CAS number 68-11-1. This chemical substance has a molecular weight of 92.12 g/mol and contains both carboxylic acid and thiol functional groups. It is classified as a hazardous substance with high acute toxicity and corrosive properties, requiring careful handling and storage procedures in industrial applications.

What are the physicochemical properties of 2-sulfanylacetic acid?

2-sulfanylacetic acid is typically a crystalline solid at room temperature with characteristic sulfur-containing compound odor. The substance is highly soluble in water due to its carboxylic acid group and polar nature. It exhibits strong reducing properties due to the presence of the thiol group, making it reactive with oxidizing agents and metals under certain conditions.

What is 2-sulfanylacetic acid used for?

2-sulfanylacetic acid serves as an important intermediate in pharmaceutical synthesis and chemical manufacturing. It is commonly used in the production of various medications, particularly as a building block for drug compounds. Additionally, it finds applications in biochemical research, analytical chemistry, and as a reducing agent in specialized chemical processes requiring thiol functionality.

How to handle 2-sulfanylacetic acid safely?

2-sulfanylacetic acid requires strict safety measures due to its Acute Tox. 3 and Skin Corr. 1B classifications. Operators must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure, and direct skin contact must be prevented at all times.

How to store 2-sulfanylacetic acid correctly?

2-sulfanylacetic acid must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. The substance should be kept separated from oxidizing agents, bases, and metals to prevent unwanted reactions. Storage areas should be equipped with appropriate containment measures and emergency procedures due to the corrosive nature of the compound.

What to do in case of contact with 2-sulfanylacetic acid?

Immediate action is required for any contact with 2-sulfanylacetic acid due to its corrosive properties. For skin contact, immediately flush the affected area with large amounts of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move the person to fresh air and consult a physician immediately.

How to dispose of 2-sulfanylacetic acid properly?

2-sulfanylacetic acid disposal must comply with local and European waste regulations as it is classified as hazardous waste. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment facilities. Neutralization procedures should only be performed by qualified personnel, and all disposal activities must be documented according to regulatory requirements.

How to transport 2-sulfanylacetic acid?

2-sulfanylacetic acid is classified under ADR Class 8 (corrosive substances) Packing Group II, requiring specialized transport procedures. The substance must be packaged in UN-approved containers with appropriate labeling including GHS06 and GHS05 pictograms and 'Danger' signal word. Transport vehicles must carry proper documentation and emergency response information, and drivers require ADR certification for corrosive materials.

Is 2-sulfanylacetic acid subject to specific regulations?

2-sulfanylacetic acid is subject to comprehensive European chemical regulations including REACH registration and CLP classification requirements. The substance is not currently listed as an SVHC (Substance of Very High Concern) but must comply with standard chemical safety data sheet provisions, hazard communication requirements, and workplace exposure limits where applicable under occupational health regulations.

Where to buy 2-sulfanylacetic acid in Europe?

2-sulfanylacetic acid is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI provides this substance with complete regulatory documentation, safety data sheets, and technical support. The company serves industrial customers across Europe, ensuring compliance with all relevant chemical regulations and providing reliable supply chain management for hazardous materials.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.