2-bromoacetic acid

2-bromoacetic acid is an organohalogen compound with the molecular formula C2H3BrO2 and CAS number 79-08-3. This chemical substance belongs to the haloacetic acid family, featuring a bromine atom attached to the carbon adjacent to the carboxylic acid group. With a molecular weight of 138.95 g/mol, it is classified as a highly hazardous substance requiring careful handling due to its corrosive and toxic properties.

2-bromoacetic acid is typically a white to pale yellow crystalline solid at room temperature with a characteristic pungent odor. It is highly soluble in water and polar organic solvents due to its carboxylic acid functional group. The compound exhibits strong acidic properties and is hygroscopic, readily absorbing moisture from air. Its bromine substituent makes it more reactive than acetic acid, particularly in nucleophilic substitution reactions.

2-bromoacetic acid is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. It serves as an alkylating agent in organic chemistry for introducing carboxymethyl groups into various compounds. The substance is commonly employed in the production of specialty chemicals, research applications, and as a reagent in analytical chemistry. Its reactive nature makes it valuable for creating derivatives and complex molecular structures in laboratory settings.

2-bromoacetic acid requires strict safety measures due to its corrosive and toxic nature. Personal protective equipment must include chemical-resistant gloves, safety goggles, lab coat, and respiratory protection when handling. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely, as the substance can cause severe burns and irritation. Emergency washing facilities should be immediately accessible.

2-bromoacetic acid must be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers away from bases, metals, and oxidizing agents to prevent dangerous reactions. Storage areas should be equipped with appropriate spill containment measures and emergency equipment. Maintain temperatures below 25°C and protect from moisture to preserve product stability and prevent degradation.

Immediate action is required for any contact with 2-bromoacetic acid due to its corrosive properties. For skin contact, immediately flush with copious amounts of water for at least 15 minutes while removing contaminated clothing. In case of eye contact, rinse thoroughly with water for at least 15 minutes and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care immediately.

2-bromoacetic acid disposal must comply with local and European waste regulations as it is classified as hazardous waste. The substance cannot be disposed of in regular drains or municipal waste systems due to its corrosive and toxic properties. Neutralization by qualified personnel may be required before disposal. Contact licensed hazardous waste disposal companies for proper collection and treatment. Maintain detailed disposal records for regulatory compliance and environmental protection.

2-bromoacetic acid is classified as ADR Class 8 (corrosive substances) Packing Group II, requiring specialized transport procedures. Packages must bear appropriate hazard labels including corrosive substance markings and proper shipping names. Vehicles must be equipped with emergency equipment and drivers require ADR certification. The substance requires secure packaging in approved containers designed for corrosive materials, with proper documentation including safety data sheets accompanying shipments.

2-bromoacetic acid is subject to comprehensive European chemical regulations under REACH and CLP frameworks, requiring registration and classification as a hazardous substance. While not currently listed as an SVHC (Substance of Very High Concern), its Acute Toxicity 3 and Skin Corrosion 1A classifications impose strict handling, labeling, and safety data sheet requirements. Industrial users must comply with occupational exposure limits and environmental protection measures under relevant EU directives.

2-bromoacetic acid is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides comprehensive regulatory support, safety documentation, and technical expertise for hazardous chemical procurement. As a professional chemical distributor, OYSI ensures proper packaging, transport compliance, and regulatory documentation for safe delivery. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.