2-(4-tert-butylphenyl)ethanol

C12H18O

CAS5406-86-0
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

Consulting for 2-(4-tert-butylphenyl)ethanol

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Identification

CAS Number
5406-86-0
EC Number
410-020-5
UN Number
3077
Index Number
603-152-00-1
PubChem CID
79410

Physical-chemical properties

Molecular Formula
C12H18O
Molar Mass
178.27 g/mol
IUPAC Name
2-(4-tert-butylphenyl)ethanol

Chemical Identifiers

InChI
InChI=1S/C12H18O/c1-12(2,3)11-6-4-10(5-7-11)8-9-13/h4-7,13H,8-9H2,1-3H3
InChI Key
NZGMMENPUKHODD-UHFFFAOYSA-N

Overview

2-(4-tert-butylphenyl)ethanol (CAS 5406-86-0) is an aromatic alcohol compound featuring a phenylethanol structure with enhanced stability from its tert-butyl substituent. This specialized chemical intermediate belongs to the phenylethanol family and serves as a valuable building block in various industrial applications. The compound's molecular structure combines the reactivity of a primary alcohol with the stability and lipophilicity imparted by the 4-tert-butylphenyl group, making it particularly useful in synthetic chemistry and specialty chemical manufacturing. With its molecular formula C12H18O and molecular weight of 178.27 g/mol, 2-(4-tert-butylphenyl)ethanol exhibits distinct physical and chemical properties that distinguish it from simpler phenolic compounds. The tert-butyl group provides steric hindrance and increases the compound's hydrophobic character compared to unsubstituted phenylethanol derivatives. Safety considerations are paramount when handling this substance, as it is classified under several hazard categories including reproductive toxicity (Repr. 2), specific target organ toxicity following repeated exposure (STOT RE 2), serious eye damage (Eye Dam. 1), and chronic aquatic toxicity (Aquatic Chronic 2). The danger signal word and associated GHS pictograms (GHS08, GHS05, GHS09) reflect these significant health and environmental hazards. Proper personal protective equipment and handling procedures are essential during storage, transport, and use. Industrial applications for 2-(4-tert-butylphenyl)ethanol include its use as an intermediate in pharmaceutical synthesis, specialty polymer production, and fragrance chemistry. Its structural similarity to other phenolic compounds like benzene-1,4-diol makes it valuable in developing specialized chemical products where enhanced stability is required. OYSI maintains reliable supply chains for 2-(4-tert-butylphenyl)ethanol, ensuring consistent availability for European industrial customers requiring this specialized aromatic alcohol compound.

Safety & Classification

Danger
Classification:

Repr. 2; STOT RE 2 *; Eye Dam. 1; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H373

May cause damage to organs through prolonged or repeated exposure.

H318

Causes serious eye damage.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-(4-tert-Butylphenyl)ethanol, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-(4-tert-butylphenyl)ethanol?

2-(4-tert-butylphenyl)ethanol is an organic chemical compound with the molecular formula C12H18O and CAS number 5406-86-0. This aromatic alcohol features a tert-butyl substituted phenyl ring connected to an ethanol chain, giving it a molecular weight of 178.27 g/mol. It is classified as a hazardous substance with reproductive toxicity, eye damage potential, and specific target organ toxicity properties.

What are the physicochemical properties of 2-(4-tert-butylphenyl)ethanol?

2-(4-tert-butylphenyl)ethanol is a liquid aromatic alcohol at room temperature with moderate volatility. As an alcohol derivative, it exhibits polar characteristics due to its hydroxyl group, making it partially soluble in polar solvents. The compound has a distinctive aromatic odor typical of substituted phenolic compounds and appears as a clear to pale yellow liquid under normal storage conditions.

What is 2-(4-tert-butylphenyl)ethanol used for?

2-(4-tert-butylphenyl)ethanol serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of specialty chemicals, fragrance compounds, and as a building block for more complex organic molecules. The compound finds applications in research and development laboratories, as well as in industrial processes requiring specific aromatic alcohol functionalities.

How to handle 2-(4-tert-butylphenyl)ethanol safely?

Safe handling of 2-(4-tert-butylphenyl)ethanol requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Eye Dam. 1 classification. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact, and implement proper hygiene practices including thorough handwashing after handling to prevent potential reproductive and organ toxicity effects.

How to store 2-(4-tert-butylphenyl)ethanol correctly?

2-(4-tert-butylphenyl)ethanol should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and incompatible materials. Keep containers tightly sealed to prevent contamination and evaporation. Store in original labeled containers made of compatible materials, separated from strong oxidizing agents and bases. Maintain storage temperatures below 25°C and ensure proper secondary containment to prevent environmental release.

What to do in case of contact with 2-(4-tert-butylphenyl)ethanol?

In case of eye contact with 2-(4-tert-butylphenyl)ethanol, immediately flush with plenty of water for at least 15 minutes and seek medical attention due to its Eye Dam. 1 classification. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention, providing the safety data sheet to medical personnel.

How to dispose of 2-(4-tert-butylphenyl)ethanol appropriately?

2-(4-tert-butylphenyl)ethanol must be disposed of as hazardous waste according to local and national regulations due to its environmental and health hazards. Contact authorized waste disposal companies specializing in organic chemical waste. Do not discharge into drains, soil, or water bodies as it carries Aquatic Chronic 2 classification. Incineration at licensed facilities under controlled conditions is typically the preferred disposal method for this compound.

How to transport 2-(4-tert-butylphenyl)ethanol?

2-(4-tert-butylphenyl)ethanol is classified under ADR Class 9 (Miscellaneous dangerous substances) Packing Group III for transportation. It requires appropriate hazardous goods packaging, labeling, and documentation for road transport. Shipments must comply with ADR regulations including proper marking, placarding, and driver certification. Ensure containers are secure, leak-proof, and accompanied by proper shipping papers and emergency response information.

Is 2-(4-tert-butylphenyl)ethanol subject to specific regulations?

2-(4-tert-butylphenyl)ethanol is regulated under EU REACH and CLP regulations, requiring registration for commercial use and proper hazard classification labeling. While not currently listed as an SVHC substance, its Repr. 2 classification subjects it to reproductive toxicity restrictions. Users must comply with occupational exposure limits, provide safety data sheets, and implement appropriate risk management measures in accordance with European chemical safety legislation.

Where to buy 2-(4-tert-butylphenyl)ethanol in Europe?

2-(4-tert-butylphenyl)ethanol is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance, including proper documentation, safety data sheets, and quality certifications required for European markets. As a professional chemical distributor, OYSI ensures reliable supply chains and technical support for industrial and research applications across Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.