2-(2,2-diphenylacetyl)indene-1,3-dione

2-(2,2-diphenylacetyl)indene-1,3-dione is an organic chemical compound with the molecular formula C23H16O3 and CAS number 82-66-6. This substance belongs to the indanedione family and features a complex aromatic structure with diphenylacetyl and indene-1,3-dione moieties. With a molecular weight of 340.4 g/mol, it is classified as a highly toxic substance requiring careful handling due to its acute toxicity and potential for causing specific target organ toxicity upon repeated exposure.

2-(2,2-diphenylacetyl)indene-1,3-dione is a solid organic compound at room temperature with a molecular weight of 340.4 g/mol. The substance typically appears as a crystalline powder and exhibits limited water solubility due to its highly aromatic structure. Its complex molecular architecture, featuring multiple benzene rings and carbonyl groups, influences its physical properties including melting point, stability, and solubility characteristics in various organic solvents.

2-(2,2-diphenylacetyl)indene-1,3-dione is primarily used as a specialized chemical intermediate in pharmaceutical and fine chemical synthesis. Its unique molecular structure makes it valuable in research applications and as a building block for more complex organic compounds. The substance may also find applications in analytical chemistry and materials science research. Due to its high toxicity classification, its use is restricted to professional and industrial settings with appropriate safety measures.

2-(2,2-diphenylacetyl)indene-1,3-dione must be handled with extreme caution due to its Acute Tox. 2 and STOT RE 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact, inhalation, and ingestion. Work in designated areas with emergency eyewash and shower facilities readily available. Only trained personnel should handle this substance following strict safety protocols and risk assessments.

2-(2,2-diphenylacetyl)indene-1,3-dione should be stored in tightly sealed, original containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Storage areas must be secure and accessible only to authorized personnel due to the substance's high toxicity. Keep away from incompatible materials including strong oxidizing agents and bases. Ensure proper labeling with hazard pictogrammes GHS06 and GHS08, and maintain an inventory system for tracking quantities and storage duration.

Immediate medical attention is required for any contact with 2-(2,2-diphenylacetyl)indene-1,3-dione due to its high acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. Never induce vomiting if ingested. Contact poison control center or emergency medical services immediately, providing the safety data sheet to medical personnel.

2-(2,2-diphenylacetyl)indene-1,3-dione must be disposed of as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. The substance cannot be disposed of via regular waste streams due to its ADR Class 6.1 classification and high toxicity. Disposal must comply with local and European waste regulations including the Waste Framework Directive. Maintain proper documentation of disposal activities and ensure transport by certified hazardous waste carriers following ADR requirements.

2-(2,2-diphenylacetyl)indene-1,3-dione is classified as ADR Class 6.1, Packing Group I, indicating it is a highly toxic substance requiring special transport provisions. Transportation must comply with ADR regulations using appropriate packaging, labeling, and documentation. Only certified carriers authorized for dangerous goods transport can handle shipments. Packages must display proper hazard labels and shipping papers must include emergency response information. Vehicle placarding and driver certification are mandatory for road transport within Europe.

2-(2,2-diphenylacetyl)indene-1,3-dione is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as an SVHC substance, its Acute Tox. 2 and STOT RE 1 classifications impose strict handling, labeling, and safety data sheet requirements. The substance may be subject to national restrictions on use and distribution. Import, manufacture, and use must comply with relevant authorization and notification procedures under European chemical legislation.

2-(2,2-diphenylacetyl)indene-1,3-dione is available through OYSI, a specialized European distributor of high-quality chemical products. As an experienced chemical supplier, OYSI ensures compliance with all relevant European regulations including REACH and ADR transport requirements. The company provides proper documentation, safety data sheets, and technical support for professional customers. Given the substance's high toxicity classification, purchases are restricted to qualified industrial and research customers with appropriate handling capabilities and safety infrastructure.