2-(2,2-diphenylacetyl)indene-1,3-dione
C23H16O3
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Identification
- CAS Number
- 82-66-6
- EC Number
- 201-434-5
- UN Number
- 2588
- Index Number
- 606-038-00-X
- PubChem CID
- 6719
Physical-chemical properties
- Molecular Formula
- C23H16O3
- Molar Mass
- 340.40 g/mol
- IUPAC Name
- 2-(2,2-diphenylacetyl)indene-1,3-dione
Chemical Identifiers
- InChI
- InChI=1S/C23H16O3/c24-21-17-13-7-8-14-18(17)22(25)20(21)23(26)19(15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14,19-20H
- InChI Key
- JYGLAHSAISAEAL-UHFFFAOYSA-N
Overview
2-(2,2-diphenylacetyl)indene-1,3-dione (CAS 82-66-6) is an organic compound characterized by its indandione structure and diphenylacetyl substituent, classified under acute toxicity category 2. This specialized chemical compound, with the molecular formula C23H16O3 and a molecular weight of 340.4 g/mol, belongs to the indandione family of organic compounds. The molecule features a distinctive structure combining an indene-1,3-dione core with a 2,2-diphenylacetyl group, which imparts unique chemical properties and reactivity patterns. As EC number 201-434-5, this substance is well-established in European chemical databases and regulatory frameworks. The compound presents significant safety considerations, classified as Acute Tox. 2 and STOT RE 1 under GHS classification, requiring careful handling protocols. The danger signal word and associated GHS06 and GHS08 pictograms indicate both acute toxicity and specific target organ toxicity concerns. Transportation falls under ADR class 6.1, reflecting its toxic properties and necessitating specialized logistics arrangements. In industrial applications, 2-(2,2-diphenylacetyl)indene-1,3-dione serves primarily as an intermediate in pharmaceutical synthesis and specialty chemical manufacturing. Its unique structural features make it valuable in the development of anticoagulant compounds and related therapeutic agents. The compound also finds application in research and development activities focused on indandione derivatives, where it shares chemical pathways with related aromatic compounds like N-methylaniline and phenylhydrazine in certain synthetic routes. OYSI maintains reliable supply chains for this specialized chemical compound, ensuring consistent availability for European industrial customers requiring high-quality technical grade materials.
Safety & Classification
Acute Tox. 2 *; STOT RE 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2588 |
| ADR Class | 6.1 |
| Packing Group | I |
| Tunnel Code | C/E |
| Proper Shipping Name | Diphacinon (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-(2,2-diphenylacetyl)indene-1,3-dione?
2-(2,2-diphenylacetyl)indene-1,3-dione is an organic chemical compound with the molecular formula C23H16O3 and CAS number 82-66-6. This substance has a molecular weight of 340.4 g/mol and belongs to the indene-dione family of compounds. It is classified as a highly hazardous substance with acute toxicity properties and potential for causing specific target organ toxicity through repeated exposure.
What are the physicochemical properties of 2-(2,2-diphenylacetyl)indene-1,3-dione?
2-(2,2-diphenylacetyl)indene-1,3-dione is a solid organic compound at room temperature with a complex aromatic structure containing three benzene rings and two ketone groups. The substance has a molecular weight of 340.4 g/mol and is characterized by its indene-dione backbone substituted with a diphenylacetyl group. Specific physical properties such as melting point, solubility, and appearance may vary depending on purity and crystalline form.
What is 2-(2,2-diphenylacetyl)indene-1,3-dione used for?
2-(2,2-diphenylacetyl)indene-1,3-dione is primarily used as a research chemical and intermediate in organic synthesis. Its indene-dione structure makes it valuable for pharmaceutical research, particularly in the development of anticoagulant compounds and other bioactive molecules. The substance may also serve as a building block in the synthesis of complex organic compounds for various industrial applications, though its high toxicity limits its widespread commercial use.
How to handle 2-(2,2-diphenylacetyl)indene-1,3-dione safely?
2-(2,2-diphenylacetyl)indene-1,3-dione requires extreme caution during handling due to its Acute Tox. 2 and STOT RE 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in a well-ventilated area or fume hood. Avoid skin contact, inhalation, and ingestion. Use appropriate laboratory techniques and ensure emergency procedures are readily available before handling this dangerous substance.
How to store 2-(2,2-diphenylacetyl)indene-1,3-dione correctly?
2-(2,2-diphenylacetyl)indene-1,3-dione must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and properly labeled with hazard information. Storage areas should be restricted to authorized personnel only due to the substance's high toxicity. Implement appropriate secondary containment measures and ensure compatibility with storage container materials. Regular inspection of storage conditions and container integrity is essential.
What to do in case of contact with 2-(2,2-diphenylacetyl)indene-1,3-dione?
Immediate action is critical if contact with 2-(2,2-diphenylacetyl)indene-1,3-dione occurs. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with water for 15 minutes. If ingested, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel.
How to dispose of 2-(2,2-diphenylacetyl)indene-1,3-dione properly?
2-(2,2-diphenylacetyl)indene-1,3-dione must be disposed of as hazardous waste through licensed waste disposal companies in accordance with local and European regulations. The substance cannot be disposed of in regular waste streams due to its high toxicity classification. Incineration at appropriate high-temperature facilities is typically the preferred disposal method. Always consult current waste regulations and engage certified hazardous waste contractors for proper disposal procedures.
How to transport 2-(2,2-diphenylacetyl)indene-1,3-dione?
2-(2,2-diphenylacetyl)indene-1,3-dione is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating the highest level of toxicity for transport purposes. Transportation requires specialized packaging, proper labeling with toxic substance markings, and appropriate shipping documentation. Only qualified carriers experienced in handling Class 6.1 dangerous goods should transport this substance. Compliance with ADR regulations and proper emergency response information is mandatory.
Is 2-(2,2-diphenylacetyl)indene-1,3-dione subject to special regulations?
2-(2,2-diphenylacetyl)indene-1,3-dione is subject to strict regulatory oversight under European CLP regulation due to its Acute Tox. 2 and STOT RE 1 classifications. While not currently listed as a SVHC substance, it requires comprehensive safety data sheets, proper labeling with GHS06 and GHS08 pictograms, and the danger signal word. Users must comply with REACH registration requirements and implement appropriate risk management measures.
Where to buy 2-(2,2-diphenylacetyl)indene-1,3-dione in Europe?
2-(2,2-diphenylacetyl)indene-1,3-dione is available through OYSI, a specialized European distributor of chemical products. OYSI provides this highly regulated substance to qualified customers with appropriate handling capabilities and regulatory compliance. Due to the substance's high toxicity classification and transport restrictions, procurement requires proper documentation, safety certifications, and adherence to strict handling protocols. Contact OYSI directly for availability and purchasing requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.