2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is an organic chemical compound with the molecular formula C23H15ClO3 and CAS number 3691-35-8. This substance has a molecular weight of 374.8 g/mol and features a complex structure containing chlorophenyl, phenyl, and indene-dione groups. It is classified as an extremely hazardous chemical with multiple toxicity concerns including reproductive toxicity, acute toxicity, and environmental hazards, requiring careful handling and specialized safety measures.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is a solid organic compound at room temperature with a molecular weight of 374.8 g/mol. The substance contains chlorine, carbon, hydrogen, and oxygen atoms in its molecular structure (C23H15ClO3). As an indene-dione derivative with aromatic substituents, it likely exhibits limited water solubility but may be soluble in organic solvents. Specific physical properties such as melting point, boiling point, and exact appearance should be confirmed through technical data sheets.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is primarily used as an intermediate in pharmaceutical synthesis and chemical research applications. Its complex aromatic structure makes it valuable for developing pharmaceutical compounds and specialty chemicals. Due to its high toxicity classification (Acute Tox. 1, Repr. 1B), its use is restricted to specialized industrial processes and research facilities with appropriate safety infrastructure. The substance requires professional handling and is typically employed in controlled manufacturing environments for the production of more complex chemical entities.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione requires maximum safety precautions due to its Acute Tox. 1 and Repr. 1B classifications. Essential PPE includes full-face respiratory protection, chemical-resistant gloves, protective clothing, and safety goggles. Work must be conducted in well-ventilated areas or fume hoods to prevent inhalation exposure. Avoid skin contact, ingestion, and inhalation. Emergency procedures and safety equipment should be readily available. Only trained personnel should handle this substance following strict safety protocols and workplace exposure limits.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed, labeled containers made of compatible materials to prevent contamination and exposure. Storage areas should be secured with restricted access due to the substance's high toxicity. Implement appropriate spill containment measures and maintain emergency response equipment nearby. Regular inventory checks and proper segregation from other chemicals are essential to ensure safe storage conditions and regulatory compliance.

Immediate medical attention is required for any exposure to 2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione due to its Acute Tox. 1 classification. For skin contact, immediately remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Contact poison control centers and provide the safety data sheet to medical personnel for proper treatment guidance.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione must be disposed of as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. Due to its multiple hazard classifications including acute toxicity and environmental hazards, incineration at high temperatures in authorized facilities is typically required. Never dispose of this substance in regular waste streams, sewers, or the environment. Consult local environmental regulations and waste disposal authorities for specific requirements. Maintain proper documentation throughout the disposal process to ensure regulatory compliance.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is classified as ADR Class 6.1 (toxic substances) Packing Group I, indicating maximum danger level for transport. Transportation requires UN-approved packaging, proper hazardous goods documentation, and trained personnel. Vehicles must display appropriate placards and emergency information. Shipments must comply with international dangerous goods regulations (ADR/RID for road/rail, IMDG for sea, IATA for air). Only authorized carriers experienced in handling highly toxic chemicals should transport this substance, ensuring emergency response capabilities are available.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is subject to extensive chemical safety regulations under REACH and CLP frameworks in Europe. Its multiple hazard classifications (Repr. 1B, Acute Tox. 1, STOT RE 1) trigger strict handling requirements, exposure limits, and safety documentation obligations. While not currently listed as an SVHC, its toxicity profile may subject it to authorization procedures or restrictions. Companies must maintain comprehensive safety data sheets, conduct risk assessments, and implement appropriate risk management measures throughout the supply chain.

2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. As a highly toxic substance requiring professional handling, it is only supplied to qualified industrial users and research institutions with appropriate safety infrastructure. OYSI ensures compliance with all regulatory requirements including proper documentation, packaging, and transportation. Contact OYSI directly to discuss availability, technical specifications, and regulatory compliance requirements for your specific application needs.