2-(2-nitrooxyethoxy)ethyl nitrate

C4H8N2O7

CAS693-21-0
GHS01 Gefahrensymbol: Explosionsgefährlich – Explodierende Bombe
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
Danger

Consulting for 2-(2-nitrooxyethoxy)ethyl nitrate

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Identification

CAS Number
693-21-0
EC Number
211-745-8
UN Number
Index Number
603-033-00-4
PubChem CID
61198

Physical-chemical properties

Molecular Formula
C4H8N2O7
Molar Mass
196.12 g/mol
IUPAC Name
2-(2-nitrooxyethoxy)ethyl nitrate

Chemical Identifiers

InChI
InChI=1S/C4H8N2O7/c7-5(8)12-3-1-11-2-4-13-6(9)10/h1-4H2
InChI Key
LYAGTVMJGHTIDH-UHFFFAOYSA-N

Overview

2-(2-nitrooxyethoxy)ethyl nitrate (CAS 693-21-0) is an organic nitrate ester compound with explosive properties and high acute toxicity. This specialized chemical compound, also known by its EC number 211-745-8, represents a dinitrate ester with the molecular formula C4H8N2O7 and a molecular weight of 196.12 g/mol. The substance belongs to the family of nitrate esters, characterized by the presence of nitrooxy functional groups that contribute to its explosive nature and biological activity. Its structure features two nitrate groups connected through an ethylene glycol bridge, making it a symmetric dinitrate compound. The compound presents significant safety considerations due to its classification under multiple hazard categories. It is classified as an explosive substance (Expl. 1.1) with the highest level of acute toxicity (Acute Tox. 1 and 2), requiring extreme caution during handling, storage, and transportation. The substance also exhibits specific target organ toxicity following repeated exposure (STOT RE 2) and poses chronic aquatic toxicity concerns (Aquatic Chronic 3). These hazard classifications necessitate specialized handling procedures and appropriate safety equipment when working with this material. In industrial applications, this nitrate ester finds use primarily in specialized explosive formulations and as an intermediate in pharmaceutical synthesis, particularly in the development of vasodilator medications. It shares certain characteristics with other explosive compounds such as 2-methyl-1,3,5-trinitrobenzene, though its dinitrate structure provides distinct reactivity profiles. The compound may also serve as a research chemical for studies involving nitrate ester chemistry and related metabolic pathways. OYSI maintains technical-grade 2-(2-nitrooxyethoxy)ethyl nitrate in its specialized chemical portfolio, available for qualified industrial customers with appropriate handling capabilities and regulatory compliance.

Safety & Classification

Danger
Classification:

Expl. 1.1; Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *; STOT RE 2 *; Aquatic Chronic 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H201

Explosive; mass explosion hazard.

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Frequently Asked Questions

What is 2-(2-nitrooxyethoxy)ethyl nitrate?

2-(2-nitrooxyethoxy)ethyl nitrate is an organic nitrate ester compound with the molecular formula C4H8N2O7 and CAS number 693-21-0. This chemical substance has a molecular weight of 196.12 g/mol and belongs to the class of nitrooxy compounds. It is characterized by its explosive properties (Class 1.1) and high acute toxicity, making it a highly hazardous material requiring specialized handling and safety protocols in industrial applications.

What are the physicochemical properties of 2-(2-nitrooxyethoxy)ethyl nitrate?

2-(2-nitrooxyethoxy)ethyl nitrate is a nitrate ester with a molecular weight of 196.12 g/mol and molecular formula C4H8N2O7. As an organic nitrate compound, it typically exists as a liquid at room temperature. The presence of nitrate groups in its structure contributes to its explosive characteristics and chemical instability. Specific physical properties such as exact melting point, boiling point, and solubility data require laboratory analysis for precise determination.

What is 2-(2-nitrooxyethoxy)ethyl nitrate used for?

2-(2-nitrooxyethoxy)ethyl nitrate is primarily used in specialized industrial applications requiring energetic materials due to its explosive properties (Class 1.1). This compound may serve as an intermediate in chemical synthesis or as a component in formulations where controlled explosive characteristics are needed. Given its high toxicity and explosive nature, its applications are strictly limited to professional and industrial settings with appropriate safety infrastructure and expertise.

How to handle 2-(2-nitrooxyethoxy)ethyl nitrate safely?

2-(2-nitrooxyethoxy)ethyl nitrate requires extreme safety precautions due to its explosive (Class 1.1) and highly toxic properties. Personnel must wear full protective equipment including chemical-resistant gloves, protective clothing, and respiratory protection. Work must be conducted in well-ventilated areas away from ignition sources, heat, and incompatible materials. Only trained professionals should handle this substance, following strict protocols to prevent exposure, contamination, and accidental detonation.

How to store 2-(2-nitrooxyethoxy)ethyl nitrate correctly?

2-(2-nitrooxyethoxy)ethyl nitrate must be stored in specialized explosive storage facilities meeting regulatory requirements for Class 1.1 materials. Storage areas should be cool, dry, well-ventilated, and isolated from incompatible substances, ignition sources, and high-traffic areas. Containers must be appropriate for explosive materials and properly labeled. Access should be restricted to authorized personnel only, with emergency procedures and fire suppression systems specifically designed for explosive materials readily available.

What to do in case of contact with 2-(2-nitrooxyethoxy)ethyl nitrate?

Immediate emergency response is critical due to the compound's high acute toxicity (Classes 1 and 2). For skin contact, remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. If inhaled, move victim to fresh air immediately and seek medical attention. For eye contact, rinse thoroughly with water. In all cases of exposure, contact emergency services and poison control immediately while providing the safety data sheet to medical personnel.

How to dispose of 2-(2-nitrooxyethoxy)ethyl nitrate appropriately?

2-(2-nitrooxyethoxy)ethyl nitrate requires specialized disposal through licensed hazardous waste contractors experienced with explosive materials. Standard waste disposal methods are prohibited due to its explosive classification (Class 1.1). Disposal must comply with local, national, and international regulations for explosive and toxic substances. The waste must be properly characterized, packaged according to explosive material requirements, and transported by certified carriers to approved treatment or destruction facilities equipped for energetic materials.

How to transport 2-(2-nitrooxyethoxy)ethyl nitrate?

2-(2-nitrooxyethoxy)ethyl nitrate requires specialized transportation protocols for dangerous goods due to its explosive and toxic properties. Transport must comply with ADR/RID regulations for hazardous materials, requiring appropriate classification, packaging, labeling, and documentation. Only certified carriers with explosive materials transportation permits can handle shipments. Vehicles must meet specific safety requirements, and transport routes may be restricted. Professional logistics companies specializing in dangerous goods should manage all transportation arrangements.

Is 2-(2-nitrooxyethoxy)ethyl nitrate subject to specific regulations?

2-(2-nitrooxyethoxy)ethyl nitrate is subject to extensive regulatory oversight under multiple frameworks including REACH registration requirements, CLP classification and labeling regulations, and explosive materials legislation. Its classification as Explosive 1.1 and highly toxic substance triggers strict controls on manufacturing, storage, transport, and use. The compound is not currently listed as an SVHC but requires compliance with occupational safety regulations and may be subject to additional national restrictions on explosive materials.

Where to buy 2-(2-nitrooxyethoxy)ethyl nitrate in Europe?

2-(2-nitrooxyethoxy)ethyl nitrate is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous materials. Due to its explosive and highly toxic nature, procurement requires proper authorization, compliance documentation, and adherence to strict regulatory requirements. OYSI provides professional support for regulatory compliance and safe handling protocols. Customers must demonstrate legitimate industrial use, appropriate safety infrastructure, and necessary permits before purchase authorization.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.