2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one is an organic chemical compound with the molecular formula C12H14ClNO2 and CAS number 81777-89-1. This oxazolidinone derivative features a five-membered heterocyclic ring containing nitrogen and oxygen, substituted with a chlorophenylmethyl group. With a molecular weight of 239.7 g/mol, it belongs to the class of substituted oxazolidinones and requires careful handling due to its toxicological properties and environmental hazard classification.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one is a solid organic compound at room temperature with a molecular weight of 239.7 g/mol. The presence of the chlorophenyl group and oxazolidinone ring influences its polarity and solubility characteristics. The compound contains both hydrophobic aromatic components and polar functional groups, affecting its dissolution behavior in various solvents. Specific physical properties such as melting point, boiling point, and exact solubility data should be obtained from detailed technical specifications.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one serves as an important intermediate in pharmaceutical and fine chemical synthesis. Oxazolidinone derivatives are commonly utilized in the development of antimicrobial agents and other bioactive compounds. This specific compound may be employed in research applications, drug discovery processes, or as a building block for more complex molecular structures. Its applications are primarily found in specialized chemical manufacturing and pharmaceutical research facilities requiring high-purity intermediates.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one requires careful handling due to its Acute Tox. 4 classification and Warning signal word. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate laboratory clothing. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin and eye contact, and prevent ingestion. Wash hands thoroughly after handling and before eating or drinking. Keep containers tightly closed when not in use and follow established laboratory safety protocols.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one should be stored in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. Maintain storage areas with adequate ventilation and controlled temperature conditions. Keep the substance away from incompatible materials and ensure containers are properly labeled with hazard information. Storage facilities should comply with local chemical storage regulations and include appropriate containment measures. Regular inspection of containers for integrity and proper segregation from other chemicals is essential for safe storage.

Immediate action is required following contact with 2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek medical attention. Always consult the safety data sheet and contact emergency services or poison control if symptoms develop.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one must be disposed of according to local and national hazardous waste regulations due to its toxic and environmental hazard classifications. Contact licensed hazardous waste disposal companies for proper collection and treatment. Do not discharge into sewers, waterways, or soil due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Contaminated containers should also be treated as hazardous waste. Maintain proper documentation of disposal activities and follow your organization's waste management procedures.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transport purposes. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Packages must bear proper shipping names, UN numbers, and hazard labels. Transport vehicles should carry appropriate emergency response information and drivers must have proper training. Ensure packages are secured to prevent damage during transit and comply with quantity limitations for different transport categories.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one is subject to European REACH regulation requiring registration for manufacture or import above certain tonnages. The substance is classified under CLP regulation with specific hazard classes (Acute Tox. 4, Aquatic Acute 1, Aquatic Chronic 1) and corresponding GHS pictograms (GHS07, GHS09). It is not currently listed as a SVHC (Substance of Very High Concern). Users must comply with occupational health and safety regulations, environmental protection laws, and proper chemical inventory reporting requirements in their respective jurisdictions.

2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to qualified customers including research institutions, pharmaceutical companies, and chemical manufacturers. As a regulated chemical substance, procurement requires proper documentation including intended use declarations and compliance with applicable regulations. Contact OYSI directly for availability, technical specifications, safety data sheets, and regulatory support to ensure compliant purchasing and handling of this specialized chemical intermediate.