2,6-dichloro-4-(trifluoromethyl)aniline

2,6-dichloro-4-(trifluoromethyl)aniline is an aromatic amine compound with the molecular formula C7H4Cl2F3N and CAS number 24279-39-8. This halogenated aniline derivative contains both chlorine and trifluoromethyl substituents on the benzene ring, giving it unique chemical properties. With a molecular weight of 230.01 g/mol, it is classified as a hazardous substance requiring careful handling due to its toxicity and environmental impact potential.

2,6-dichloro-4-(trifluoromethyl)aniline is a solid organic compound at room temperature, typically appearing as a crystalline powder. The presence of multiple halogen atoms (chlorine and fluorine) significantly affects its polarity and solubility characteristics. The trifluoromethyl group increases lipophilicity while the amine group provides some polar character. Its exact melting point, boiling point, and solubility data should be confirmed through technical specifications from suppliers.

2,6-dichloro-4-(trifluoromethyl)aniline is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its unique substitution pattern makes it valuable for producing specialized compounds where both electron-withdrawing effects and specific positioning are required. The compound serves as a building block in the manufacture of pesticides, herbicides, and pharmaceutical active ingredients, particularly where fluorinated aromatic amines are needed in the molecular structure.

2,6-dichloro-4-(trifluoromethyl)aniline requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction systems to prevent inhalation exposure. The compound is classified as Acute Tox. 4, Skin Irrit. 2, and Skin Sens. 1, indicating potential for toxicity, skin irritation, and sensitization. Avoid direct skin contact and ensure proper training before handling.

2,6-dichloro-4-(trifluoromethyl)aniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled with hazard information. Store away from strong oxidizers, acids, and bases that could react with the amine functional group. Ensure storage areas have appropriate spill containment measures and restricted access due to the compound's toxicity and environmental hazard classification.

Immediate action is required upon contact with 2,6-dichloro-4-(trifluoromethyl)aniline due to its skin irritation and sensitization potential. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention if symptoms persist or for any significant exposure.

2,6-dichloro-4-(trifluoromethyl)aniline must be disposed of as hazardous waste due to its toxicity and environmental impact (Aquatic Acute 1, Aquatic Chronic 1). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never discharge to sewers, waterways, or general waste streams. Follow local and national regulations including REACH and waste framework directives. Incineration at authorized high-temperature facilities is typically the preferred disposal method for halogenated aromatic compounds.

2,6-dichloro-4-(trifluoromethyl)aniline is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Packages must display proper shipping names, UN numbers, and hazard labels. Transportation should be carried out by trained personnel with appropriate emergency response procedures and equipment readily available during transit.

2,6-dichloro-4-(trifluoromethyl)aniline is subject to various chemical regulations including REACH registration requirements for manufacture and import in the European Union. It must be classified and labeled according to CLP regulation with Warning signal word and appropriate GHS pictograms (GHS07, GHS09). The compound is not currently listed as a Substance of Very High Concern (SVHC), but users must comply with occupational exposure limits and environmental protection requirements.

2,6-dichloro-4-(trifluoromethyl)aniline is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides this compound to pharmaceutical, agrochemical, and research industries across Europe with proper documentation including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures compliance with European chemical regulations and provides technical support for safe handling and application guidance.