2,6-dichloro-4-(trifluoromethyl)aniline

2,6-dichloro-4-(trifluoromethyl)aniline is an aromatic amine compound with the molecular formula C7H4Cl2F3N and CAS number 24279-39-8. This halogenated aniline derivative features two chlorine atoms at positions 2 and 6, and a trifluoromethyl group at position 4 on the benzene ring. With a molecular weight of 230.01 g/mol, it belongs to the class of substituted anilines commonly used in chemical synthesis and industrial applications.

2,6-dichloro-4-(trifluoromethyl)aniline typically appears as a crystalline solid at room temperature due to its aromatic structure and multiple halogen substituents. The presence of electron-withdrawing chlorine and trifluoromethyl groups affects its solubility profile, generally making it less soluble in water but more soluble in organic solvents. The compound's physical properties are influenced by intermolecular interactions between the halogenated aromatic rings.

2,6-dichloro-4-(trifluoromethyl)aniline serves as an important intermediate in pharmaceutical and agrochemical synthesis. The compound is primarily used in the production of pesticides, herbicides, and pharmaceutical active ingredients where halogenated aniline derivatives are required. Its unique substitution pattern makes it valuable for creating molecules with specific biological activities, particularly in crop protection products and specialized chemical manufacturing processes.

2,6-dichloro-4-(trifluoromethyl)aniline requires careful handling due to its acute toxicity and skin sensitization properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. The compound carries GHS07 and GHS09 pictograms, indicating health and environmental hazards that require appropriate safety measures during handling.

2,6-dichloro-4-(trifluoromethyl)aniline should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and protected from moisture and light to maintain product stability. Due to its environmental hazard classification (Aquatic Acute 1), storage areas must have appropriate containment measures to prevent environmental release. Store separately from strong oxidizing agents and acids to avoid potential reactions.

2,6-dichloro-4-(trifluoromethyl)aniline contact requires immediate first aid due to its skin irritation and sensitization properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Always seek professional medical advice after any significant exposure.

2,6-dichloro-4-(trifluoromethyl)aniline disposal must follow strict environmental regulations due to its aquatic toxicity classification. The compound should never be discharged to sewers, waterways, or soil. Disposal must be conducted through licensed waste management companies specializing in hazardous chemical waste. Incineration at approved high-temperature facilities is typically the preferred method, ensuring complete destruction while preventing environmental contamination and complying with local waste regulations.

2,6-dichloro-4-(trifluoromethyl)aniline is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transport purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must use UN-approved packaging and display proper hazard labels including GHS07 and GHS09 pictograms. Transportation should only be conducted by carriers trained in dangerous goods handling and familiar with emergency response procedures.

2,6-dichloro-4-(trifluoromethyl)aniline is regulated under European REACH and CLP regulations, requiring registration and proper classification. While not currently listed as a Substance of Very High Concern (SVHC), its hazard profile including acute toxicity and environmental impact subjects it to standard chemical safety requirements. Manufacturers and importers must comply with safety data sheet provisions, exposure assessments, and risk management measures under REACH legislation.

2,6-dichloro-4-(trifluoromethyl)aniline is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to qualified industrial customers with appropriate handling capabilities and regulatory compliance. As a professional chemical distributor, OYSI ensures proper documentation, safety data sheets, and regulatory compliance for shipments throughout Europe, serving pharmaceutical, agrochemical, and specialty chemical industries.