1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene is a specialized organofluorine compound with CAS number 130841-23-5. This chemical features a benzene ring substituted with two chlorine atoms, one nitro group, and a hexafluoropropoxy group. With a molecular formula of C9H3Cl2F6NO3 and molecular weight of 358.02 g/mol, it represents a complex halogenated aromatic compound primarily used in specialized chemical applications.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene is a dense organic compound with significant halogen content. The presence of multiple fluorine atoms and chlorine substituents typically results in high chemical stability and low volatility. The nitro group contributes to its electron-withdrawing character, while the hexafluoropropoxy group imparts unique solubility characteristics, generally showing poor water solubility but better compatibility with fluorinated solvents.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene serves as a specialized intermediate in pharmaceutical and agrochemical synthesis. Its unique combination of electron-withdrawing groups and fluorinated substituents makes it valuable for developing compounds requiring specific biological activity or chemical stability. The compound may also find applications in materials science, particularly in the development of fluorinated polymers or specialized coatings requiring chemical resistance.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene requires careful handling due to its Acute Tox. 4 and Skin Sens. 1 classifications. Essential protective equipment includes nitrile gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume hood extraction. Avoid inhalation and skin contact, as the compound may cause sensitization. Always wash hands thoroughly after handling and ensure proper training before use.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight. Keep away from heat sources, strong oxidizers, and incompatible materials. Store in original packaging with proper labeling including GHS07 and GHS09 pictograms. Ensure storage area has appropriate spill containment measures and restricted access. Regular inspection of containers for integrity is recommended.

Immediate action is required following contact with 1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop, particularly for skin sensitization reactions. Never induce vomiting if swallowed.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene must be disposed of through licensed hazardous waste contractors due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). The compound cannot be disposed of in regular waste streams or sewers. High-temperature incineration at specialized facilities is typically required for fluorinated compounds. Maintain detailed waste tracking documentation and follow all local, national, and EU regulations for hazardous waste disposal.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation. Packages must bear appropriate UN identification numbers and hazard labels. Use approved packaging that meets UN specifications for Class 9 materials. Transport vehicles require appropriate placarding and emergency information. Drivers need ADR certification for dangerous goods transport. Ensure proper documentation including transport documents and safety data sheets accompany shipments.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene falls under EU REACH regulation requiring registration for commercial use. The compound is classified under CLP regulation with Warning signal word and specific hazard statements. It is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with occupational exposure limits, environmental discharge restrictions, and proper hazard communication requirements including safety data sheet provision and worker training.

1,4-dichloro-2-(1,1,2,3,3,3-hexafluoropropoxy)-5-nitrobenzene is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial and research customers with proper handling capabilities. The company ensures full regulatory compliance, proper packaging, and complete documentation including safety data sheets. Contact OYSI directly for availability, technical specifications, and pricing information. Purchases require verification of intended use and appropriate safety measures.