1-methylpyrrolidin-2-one

1-methylpyrrolidin-2-one is an organic chemical compound with the molecular formula C5H9NO and CAS number 872-50-4. This cyclic amide belongs to the pyrrolidinone family and has a molecular weight of 99.13 g/mol. It is classified as a reproductive toxicant (Repr. 1B) and causes specific target organ toxicity, skin irritation, and eye irritation. The substance carries danger signal word and requires careful handling due to its hazardous properties.

1-methylpyrrolidin-2-one is a colorless to pale yellow liquid at room temperature with a characteristic mild odor. The compound is highly polar and demonstrates excellent solubility in water and most organic solvents including alcohols, ketones, and aromatic hydrocarbons. It has a relatively low molecular weight of 99.13 g/mol and exhibits hygroscopic properties, meaning it readily absorbs moisture from the atmosphere.

1-methylpyrrolidin-2-one serves primarily as a high-performance solvent in various industrial applications. It is widely used in pharmaceutical manufacturing, polymer processing, and as a reaction medium in chemical synthesis. The substance also finds applications in paint strippers, coating formulations, and as a solvent for polymer dissolution. Its excellent solvency properties make it valuable in electronics cleaning, petrochemical processing, and specialty chemical manufacturing.

1-methylpyrrolidin-2-one requires strict safety measures due to its reproductive toxicity and irritant properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work must be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Given its Repr. 1B classification, pregnant workers should avoid any exposure, and all personnel should receive proper safety training.

1-methylpyrrolidin-2-one should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. The storage area must be equipped with appropriate containment measures and maintained at controlled temperatures to prevent degradation. Keep containers away from incompatible materials and ensure proper labeling with hazard information. Access should be restricted to trained personnel only, with emergency response equipment readily available.

1-methylpyrrolidin-2-one exposure requires immediate first aid measures depending on the contact route. For skin contact, immediately remove contaminated clothing and wash the affected area with plenty of soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. Seek medical attention promptly, especially given the substance's reproductive toxicity classification.

1-methylpyrrolidin-2-one disposal must comply with local and national hazardous waste regulations due to its classification as dangerous goods. The substance should be collected in appropriate containers and disposed of through licensed hazardous waste contractors. Incineration at authorized facilities capable of handling toxic substances is typically the preferred disposal method. Never dispose of this chemical through regular waste streams, sewers, or water bodies as it poses environmental and health risks.

1-methylpyrrolidin-2-one transport requires compliance with international dangerous goods regulations, though specific ADR classification details may vary by jurisdiction. The substance must be packaged in approved containers with proper hazard labeling and documentation. Transport vehicles should be equipped with appropriate emergency equipment and drivers must hold valid dangerous goods licenses. Shipments require proper marking, placarding, and accompanying safety data sheets to ensure safe handling throughout the transport chain.

1-methylpyrrolidin-2-one is subject to comprehensive chemical safety regulations including REACH registration requirements in Europe and CLP classification obligations. The substance's Repr. 1B classification triggers specific workplace safety measures and potential restrictions on use. Companies handling this chemical must ensure proper risk assessments, employee training, and compliance with occupational exposure limits. Regular safety monitoring and reporting may be required depending on usage quantities and local regulatory frameworks.

1-methylpyrrolidin-2-one is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to industrial customers across Europe with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures product quality and maintains appropriate storage and handling procedures. Contact OYSI directly for availability, technical specifications, and delivery options tailored to your specific industrial requirements.