1-chloropropane
C3H7Cl
Consulting for 1-chloropropane
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 540-54-5
- EC Number
- 208-749-7
- UN Number
- 1278
- Index Number
- 602-018-00-X
- PubChem CID
- 10899
Physical-chemical properties
- Molecular Formula
- C3H7Cl
- Molar Mass
- 78.54 g/mol
- IUPAC Name
- 1-chloropropane
Chemical Identifiers
- InChI
- InChI=1S/C3H7Cl/c1-2-3-4/h2-3H2,1H3
- InChI Key
- SNMVRZFUUCLYTO-UHFFFAOYSA-N
Overview
1-Chloropropane (CAS 540-54-5) is an organochlorine compound with flammable properties and acute toxicity characteristics. This primary alkyl halide, also known by its IUPAC name 1-chloropropane, represents a fundamental building block in organic synthesis and industrial chemistry. With the molecular formula C3H7Cl and a molecular weight of 78.54 g/mol, this colorless liquid belongs to the family of chloroalkanes and serves as an important intermediate in various chemical processes. The compound is classified under EC number 208-749-7 and carries significant safety considerations due to its flammable nature and toxicity profile. As a Class 2 flammable liquid under GHS classification, 1-chloropropane requires careful handling protocols in industrial settings. The substance exhibits acute toxicity through multiple exposure routes, warranting the "Danger" signal word and appropriate GHS pictograms (GHS02 and GHS07). Its ADR Class 3 designation reflects its transportation requirements as a flammable liquid, necessitating specialized logistics and storage conditions. The compound finds primary applications in organic synthesis as a reagent and intermediate, particularly in pharmaceutical manufacturing and specialty chemical production. It serves as an effective alkylating agent in various chemical reactions and can be utilized in the preparation of other organochlorine compounds. Similar to other chloroalkanes like 3-chloropentane, it demonstrates utility in selective synthetic pathways where controlled reactivity is essential. Industrial applications also extend to solvent systems and extraction processes, where its specific polarity and boiling point characteristics provide advantages over alternative compounds. The substance's reactivity profile makes it valuable in producing surfactants and other specialty chemicals. OYSI maintains reliable supply chains for 1-chloropropane to support European industrial customers requiring this essential chemical intermediate.
Safety & Classification
Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1278 |
| ADR Class | 3 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 1-Chlorpropan, rein |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1-chloropropane?
1-chloropropane is an organochlorine compound with the molecular formula C3H7Cl and CAS number 540-54-5. It belongs to the alkyl halide family, featuring a chlorine atom attached to the first carbon of a propane chain. With a molecular weight of 78.54 g/mol, this chemical is classified as a flammable liquid and presents acute toxicity hazards, requiring careful handling in industrial applications.
What are the physicochemical properties of 1-chloropropane?
1-chloropropane is a colorless liquid at room temperature with a characteristic sweet, chloroform-like odor. It has a boiling point of approximately 46.6°C and a density of about 0.89 g/cm³. The compound is slightly soluble in water but miscible with most organic solvents including alcohols, ethers, and hydrocarbons. Its vapor pressure is relatively high, making it volatile at ambient temperatures.
What is 1-chloropropane used for?
1-chloropropane serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of other chemicals through nucleophilic substitution reactions and as a solvent in specialized industrial processes. The compound also finds application in research laboratories for synthetic chemistry work and as a reagent in the preparation of various propyl derivatives and pharmaceutical compounds.
How to handle 1-chloropropane safely?
1-chloropropane requires strict safety measures due to its flammability and toxicity. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work in well-ventilated spaces or under fume hoods, away from heat sources and ignition points. Ensure emergency shower and eyewash stations are accessible, and never eat, drink, or smoke while handling this chemical.
How to store 1-chloropropane correctly?
1-chloropropane must be stored in cool, dry, well-ventilated areas away from heat sources, sparks, and open flames. Use appropriate containers made of compatible materials and keep them tightly sealed to prevent vapor release. Store separately from strong bases, metals, and oxidizing agents to avoid dangerous reactions. Maintain storage temperatures below 25°C and ensure proper grounding of containers to prevent static electricity buildup.
What to do in case of contact with 1-chloropropane?
In case of skin contact with 1-chloropropane, immediately remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes. For eye contact, flush thoroughly with water and seek medical attention. If inhaled, move the person to fresh air immediately and provide respiratory support if needed. In case of ingestion, do not induce vomiting and seek immediate medical care.
How to dispose of 1-chloropropane properly?
1-chloropropane disposal must comply with local and European waste regulations as a hazardous chemical waste. The substance cannot be poured down drains or disposed of with regular waste. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may be incinerated at high temperatures in specialized facilities equipped with appropriate emission controls to prevent environmental contamination.
How to transport 1-chloropropane?
1-chloropropane is classified under ADR transport regulations as Class 3 (flammable liquids), Packing Group II, indicating moderate danger level. Transportation requires appropriate UN-specification packaging, proper labeling with flammable liquid hazard diamonds, and compliance with quantity limitations. Vehicles must carry appropriate emergency equipment, and drivers need ADR certification. Ensure proper documentation and emergency response information accompany shipments.
Is 1-chloropropane subject to specific regulations?
1-chloropropane is regulated under European CLP regulation with mandatory hazard classification as Flam. Liq. 2 and Acute Tox. 4, requiring danger signal word and specific pictograms (GHS02, GHS07). It falls under REACH regulation for chemical registration and safety assessment. The substance is not currently listed as SVHC (Substance of Very High Concern), but users must comply with occupational exposure limits and safety data sheet requirements.
Where to buy 1-chloropropane in Europe?
1-chloropropane is available through OYSI, a specialized European distributor of technical chemicals. As professional chemical suppliers, we ensure compliance with all regulatory requirements including proper documentation, safety data sheets, and transport classifications. Our European distribution network enables reliable supply to industrial customers, research institutions, and pharmaceutical companies requiring this specialized chemical for their operations.
Services for 1-chloropropane
Order 1-chloropropane
Fast delivery across Europe
SDS Service
Request Safety Data Sheet for 1-chloropropane
Technical Consulting
Application advice for 1-chloropropane
REACH Safety Data Sheet
REACH Compliance Service
Digital Product Passport
EU-compliant product documentation
ADR Consulting for 1-chloropropane
1-chloropropane is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.