1-chlorobutane

C4H9Cl

CAS109-69-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
Danger

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Identification

CAS Number
109-69-3
EC Number
203-696-6
UN Number
1127
Index Number
602-059-00-3
PubChem CID
8005

Physical-chemical properties

Molecular Formula
C4H9Cl
Molar Mass
92.57 g/mol
IUPAC Name
1-chlorobutane

Chemical Identifiers

InChI
InChI=1S/C4H9Cl/c1-2-3-4-5/h2-4H2,1H3
InChI Key
VFWCMGCRMGJXDK-UHFFFAOYSA-N

Overview

1-Chlorobutane (CAS 109-69-3) is a primary alkyl halide with high flammability and moderate volatility characteristics. This colorless liquid belongs to the chloroalkane family and serves as an important intermediate in organic synthesis and industrial chemical processes. As a straight-chain chlorinated hydrocarbon with the molecular formula C4H9Cl, 1-chlorobutane exhibits typical properties of primary alkyl halides. The compound features a chlorine atom attached to the terminal carbon of a four-carbon butyl chain, making it highly reactive in nucleophilic substitution reactions. With a molecular weight of 92.57 g/mol, this substance demonstrates good solubility in organic solvents while remaining largely immiscible with water. The primary safety consideration for 1-chlorobutane centers on its classification as a Class 2 flammable liquid, requiring careful handling protocols and appropriate fire prevention measures. The substance carries the GHS02 pictogram and "Danger" signal word, indicating significant flammability risks that must be managed through proper storage, ventilation, and ignition source control. Industrial applications of 1-chlorobutane include its use as a solvent for various chemical processes, as an alkylating agent in pharmaceutical synthesis, and as an intermediate in the production of other organic compounds. The compound finds particular utility in laboratory settings for organic synthesis reactions, where its reactivity profile makes it valuable for creating carbon-carbon bonds. Unlike related compounds such as butanal or ethyl propanoate, 1-chlorobutane's halogenated structure provides unique synthetic possibilities in chemical manufacturing. Transportation classification under ADR Class 3 reflects the flammable nature of this material, necessitating compliance with hazardous goods regulations during shipping and handling. OYSI maintains reliable supplies of high-quality 1-chlorobutane to support diverse industrial and research applications across European markets.

Safety & Classification

Danger
Classification:

Flam. Liq. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number1127
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1-Chlorbutan
Marine PollutantNo

Frequently Asked Questions

What is 1-chlorobutane?

1-chlorobutane is an organochlorine compound with the molecular formula C4H9Cl and CAS number 109-69-3. It belongs to the alkyl halide family, featuring a chlorine atom attached to the first carbon of a four-carbon chain. With a molecular weight of 92.57 g/mol, this chemical is classified as a flammable liquid and requires careful handling due to its fire hazard properties.

What are the physicochemical properties of 1-chlorobutane?

1-chlorobutane is a colorless liquid at room temperature with a characteristic sweet, ether-like odor. It has low solubility in water but is miscible with most organic solvents including alcohols, ethers, and hydrocarbons. The compound exhibits typical properties of primary alkyl halides, with a boiling point around 78°C and density higher than water due to the presence of chlorine.

What is 1-chlorobutane used for?

1-chlorobutane serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of other chemicals through nucleophilic substitution reactions, as a solvent for certain applications, and in the synthesis of butyl derivatives. The compound also finds use in research laboratories for various chemical transformations and as a reagent in organic chemistry processes.

How to handle 1-chlorobutane safely?

1-chlorobutane requires careful handling as a flammable liquid (Class 2). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid vapor inhalation. Keep away from ignition sources, hot surfaces, and open flames. Use explosion-proof electrical equipment and ensure proper grounding of containers during transfer operations.

How to store 1-chlorobutane correctly?

1-chlorobutane must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Use tightly sealed containers made of compatible materials and keep away from oxidizing agents and strong bases. Storage areas should be equipped with appropriate fire suppression systems and spill containment measures. Maintain storage temperatures below the flashpoint and ensure containers are properly labeled according to GHS requirements.

What to do in case of contact with 1-chlorobutane?

In case of skin contact with 1-chlorobutane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if symptoms persist. In case of ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 1-chlorobutane appropriately?

1-chlorobutane disposal must comply with local and national hazardous waste regulations. The compound should be collected as halogenated organic waste and disposed of through licensed hazardous waste management facilities. Never dispose of it down drains, in soil, or with regular waste. Contact certified waste disposal companies for proper collection and treatment. Small laboratory quantities may require specific disposal protocols according to institutional guidelines.

How to transport 1-chlorobutane?

1-chlorobutane is classified under ADR Class 3 (flammable liquids), Packing Group II, indicating moderate danger. Transport requires appropriate hazardous goods packaging, labeling with GHS02 pictogram, and proper shipping documentation. Vehicles must comply with ADR regulations for flammable liquids, including appropriate equipment and driver certification. Packages must be secured to prevent damage during transit and marked with proper hazard identification.

Is 1-chlorobutane subject to specific regulations?

1-chlorobutane is subject to European REACH regulation and must be classified according to CLP regulation as Flammable Liquid Category 2 with 'Danger' signal word. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace exposure limits, proper labeling requirements, and safety data sheet provisions. Industrial users may need to fulfill additional registration or notification requirements depending on quantities handled.

Where to buy 1-chlorobutane in Europe?

1-chlorobutane is available through OYSI, a European distributor specializing in technical chemicals. OYSI provides high-quality chemical products to industrial customers across Europe with proper documentation and regulatory compliance. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for customers requiring this flammable organic compound for their industrial or research applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.