1-chlorobutane

C4H9Cl

CAS109-69-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
Danger

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Identification

CAS Number
109-69-3
EC Number
203-696-6
UN Number
1127
Index Number
602-059-00-3
PubChem CID
8005

Physical-chemical properties

Molecular Formula
C4H9Cl
Molar Mass
92.57 g/mol
IUPAC Name
1-chlorobutane

Chemical Identifiers

InChI
InChI=1S/C4H9Cl/c1-2-3-4-5/h2-4H2,1H3
InChI Key
VFWCMGCRMGJXDK-UHFFFAOYSA-N

Overview

1-Chlorobutane (CAS 109-69-3) is a primary alkyl halide featuring a four-carbon chain with terminal chlorine substitution and notable flammable properties. This halogenated hydrocarbon represents an important member of the chloroalkane family, characterized by its linear butyl structure with chlorine attached to the primary carbon position. The compound exhibits typical properties of short-chain alkyl chlorides, including moderate volatility and significant flammability, which necessitates careful handling protocols in industrial environments. As a Class 2 flammable liquid under GHS classification, 1-chlorobutane requires appropriate fire safety measures during storage and processing. The substance demonstrates typical reactivity patterns of primary alkyl halides, making it particularly valuable in nucleophilic substitution reactions and as an alkylating agent in synthetic chemistry applications. Its four-carbon chain length positions it strategically between shorter volatile chloroalkanes and longer-chain variants, offering balanced reactivity and handling characteristics. Industrial applications primarily focus on organic synthesis operations, where 1-chlorobutane serves as an effective alkylating reagent and chemical intermediate. The pharmaceutical and fine chemicals sectors utilize this compound for manufacturing various organic molecules, while the coatings industry employs it in specialized solvent formulations. Unlike related compounds such as butanal or ethyl propanoate, 1-chlorobutane's halogenated nature provides unique reactivity profiles essential for specific synthetic pathways. The compound's primary carbon chloride functionality enables efficient SN2 reaction mechanisms, making it particularly suitable for laboratory-scale syntheses and pilot plant operations requiring predictable reaction kinetics. OYSI maintains reliable supply chains for 1-chlorobutane to support European chemical manufacturing and research applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number1127
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1-Chlorbutan
Marine PollutantNo

Frequently Asked Questions

What is 1-chlorobutane?

1-Chlorobutane is an organochlorine compound with the molecular formula C4H9Cl and a molecular weight of 92.57 g/mol. It belongs to the family of alkyl halides, specifically primary alkyl chlorides. This chemical compound is classified as a flammable liquid (Flam. Liq. 2) and carries the danger signal word with GHS02 pictogram. It serves as an important intermediate in organic synthesis and various industrial applications requiring chlorinated alkyl compounds.

What are the physicochemical properties of 1-chlorobutane?

1-Chlorobutane is a colorless liquid at room temperature with a characteristic sweet, ethereal odor. It has low solubility in water due to its hydrophobic nature but is miscible with most organic solvents including alcohols, ethers, and hydrocarbons. The compound exhibits typical properties of primary alkyl halides, with a boiling point around 78°C and density lower than water. Its flammable nature requires careful handling around ignition sources.

What is 1-chlorobutane used for?

1-Chlorobutane is primarily used as an intermediate in organic synthesis for producing pharmaceuticals, agrochemicals, and other specialty chemicals. It serves as an alkylating agent in various chemical reactions and as a solvent in certain industrial processes. The compound is also utilized in the manufacture of surfactants, polymer additives, and as a building block for more complex organic molecules in research and development applications.

How to handle 1-chlorobutane safely?

1-Chlorobutane requires careful handling due to its flammable nature and potential health hazards. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and work in well-ventilated areas or under fume hoods. Eliminate all ignition sources and use non-sparking tools. Avoid skin and eye contact, and prevent inhalation of vapors. Ground all equipment to prevent static electricity buildup during transfer operations.

How to store 1-chlorobutane correctly?

1-Chlorobutane should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate containers made of compatible materials and ensure proper labeling. Keep away from oxidizing agents and strong bases which may cause incompatible reactions. Store in original containers with tight-fitting lids to prevent evaporation and contamination. Maintain storage temperatures below 25°C when possible.

What to do in case of contact with 1-chlorobutane?

In case of skin contact with 1-chlorobutane, immediately remove contaminated clothing and wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical help if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 1-chlorobutane appropriately?

1-Chlorobutane must be disposed of according to local, national, and international waste regulations as a hazardous chemical waste. Contact licensed waste disposal companies specialized in handling flammable and halogenated organic compounds. Never dispose of down drains, sewers, or in regular waste. Small quantities should be allowed to evaporate in a fume hood if permitted by local regulations, while larger amounts require professional hazardous waste disposal services.

How to transport 1-chlorobutane?

1-Chlorobutane is classified under ADR transport regulations as Class 3 (flammable liquids), Packing Group II. It requires appropriate packaging, labeling with flammable liquid hazard labels, and transport documents specifying the UN identification number. Vehicles must comply with ADR requirements for flammable liquids transport. Drivers need proper training and certification for dangerous goods transport, and emergency response information must be available during transit.

Is 1-chlorobutane subject to particular regulations?

1-Chlorobutane is subject to REACH regulation in Europe and must comply with CLP classification and labeling requirements. It is not currently listed as a Substance of Very High Concern (SVHC). Users must follow safety data sheet guidelines and ensure proper risk assessment under REACH. The substance may be subject to workplace exposure limits and environmental discharge regulations depending on local legislation and intended use applications.

Where to buy 1-chlorobutane in Europe?

1-Chlorobutane is available through OYSI, a European distributor of technical chemicals serving various industries across the continent. As a specialized chemical distributor, OYSI provides quality 1-chlorobutane with proper documentation, safety data sheets, and regulatory compliance for European markets. Contact OYSI directly for specific product grades, packaging options, and delivery arrangements to meet your industrial or research requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.