4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine
C11H20N3O3PS
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Identification
- CAS Number
- 29232-93-7
- EC Number
- 249-528-5
- UN Number
- 3082
- Index Number
- 015-134-00-5
- PubChem CID
- 34526
Physical-chemical properties
- Molecular Formula
- C11H20N3O3PS
- Molar Mass
- 305.34 g/mol
- IUPAC Name
- 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine
Chemical Identifiers
- InChI
- InChI=1S/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3
- InChI Key
- QHOQHJPRIBSPCY-UHFFFAOYSA-N
Overview
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine (CAS 29232-93-7) is an organophosphorus compound with selective biological activity and environmental persistence concerns. This specialized organophosphorus derivative combines a pyrimidine ring system with phosphorothioate functionality, resulting in a compound with distinct chemical and biological properties. With the molecular formula C11H20N3O3PS and a molecular weight of 305.34 g/mol, this substance represents an important class of synthetic organic compounds used in various industrial applications. The compound's structure features dimethoxyphosphinothioyl and diethylamino substituents attached to a methylpyrimidine core, contributing to its unique reactivity profile. From a safety perspective, this compound requires careful handling protocols due to its classification as Acute Tox. 4, STOT RE 1, Aquatic Acute 1, and Aquatic Chronic 1. The presence of GHS pictograms GHS07, GHS08, and GHS09 indicates potential health hazards, organ toxicity risks, and environmental dangers. Its ADR Class 9 classification designates it as a miscellaneous dangerous substance for transport purposes, necessitating specialized shipping and storage procedures. The compound finds applications in specialized chemical synthesis, particularly in pharmaceutical intermediate production and agricultural chemical development. Its unique phosphorothioate structure makes it valuable for developing selective biological agents and as a research tool in biochemical studies. While structurally distinct from substances like cobalt(2+) sulfate, it shares certain industrial application spaces in specialized chemical manufacturing. OYSI maintains technical-grade supplies of 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine for qualified industrial customers across Europe, supported by comprehensive safety documentation and regulatory compliance materials.
Safety & Classification
Acute Tox. 4; STOT RE 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3082 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | Pirimiphos-methyl (ISO), technisch |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is an organophosphorus compound with the molecular formula C11H20N3O3PS and CAS number 29232-93-7. This chemical substance has a molecular weight of 305.34 g/mol and belongs to the class of phosphorothioate derivatives containing a pyrimidine ring structure. It is classified as a hazardous substance with multiple safety concerns including acute toxicity, specific target organ toxicity, and aquatic environmental hazards.
What are the physicochemical properties of 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is an organophosphorus compound with a molecular weight of 305.34 g/mol and molecular formula C11H20N3O3PS. The substance contains both phosphorus and sulfur atoms within its molecular structure, along with diethylamino and methoxy functional groups attached to a methylpyrimidine core. As an organophosphate derivative, it typically exhibits moderate to high lipophilicity and may show limited water solubility due to its organic substituents.
What is 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine used for?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is primarily used as an intermediate in chemical synthesis and pharmaceutical research applications. The compound's organophosphorus structure with pyrimidine functionality makes it valuable for developing biologically active molecules and agrochemical products. It serves as a building block in organic synthesis processes where phosphorothioate chemistry is required. Industrial applications may include specialized chemical manufacturing and research and development activities in pharmaceutical and agricultural chemistry sectors.
How to handle 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine safely?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine requires careful handling due to its Acute Tox. 4 and STOT RE 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection when handling. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid direct skin and eye contact, and prevent inhalation of vapors or dust. Use appropriate containment measures to prevent environmental release due to its aquatic toxicity classification.
How to store 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine correctly?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers protected from physical damage and away from heat sources, ignition sources, and direct sunlight. Storage areas must be equipped with appropriate containment measures to prevent environmental contamination due to the substance's aquatic toxicity. Ensure storage complies with local regulations for hazardous chemicals and maintain proper inventory records.
What to do in case of contact with 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine?
Immediate action is required following contact with 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet for proper medical treatment.
How to dispose of 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine appropriately?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine must be disposed of through licensed hazardous waste management facilities due to its toxicity and environmental hazard classifications. The substance cannot be disposed of via regular waste streams or sewage systems due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Disposal must comply with local, national, and European waste regulations including the European Waste Catalogue. Contact certified waste disposal companies specializing in organophosphorus compounds for proper treatment and destruction.
How to transport 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is classified under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. Transport requires appropriate packaging conforming to UN specifications and proper hazard labeling including GHS pictogrammes GHS07, GHS08, and GHS09. Shipping documentation must include the correct technical name, UN number, and hazard classification. Transportation should be handled by carriers experienced with hazardous materials and comply with ADR regulations for dangerous goods transport.
Is 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine subject to specific regulations?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is subject to European REACH regulation and CLP classification requirements. The substance is classified with hazard categories Acute Tox. 4, STOT RE 1, Aquatic Acute 1, and Aquatic Chronic 1, requiring appropriate labeling with danger signal word and GHS pictograms. It is not currently listed as a SVHC substance. Users must comply with chemical safety regulations, workplace exposure limits, and environmental protection requirements. Professional users should maintain safety data sheets and implement appropriate risk management measures.
Where to buy 4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine in Europe?
4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this organophosphorus compound to qualified professional users including research institutions, pharmaceutical companies, and chemical manufacturers across Europe. As a regulated hazardous substance, purchases require appropriate documentation and compliance with chemical regulations. Contact OYSI directly for availability, specifications, packaging options, and technical support for your specific application requirements in chemical synthesis or research projects.
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4-dimethoxyphosphinothioyloxy-N,N-diethyl-6-methylpyrimidin-2-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.