Sodium methanolate

CH3NaO

sodium methanolate

CAS124-41-4
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
124-41-4
EC Number
204-699-5
UN Number
1431
Index Number
603-040-00-2
PubChem CID
10942334

Physical-chemical properties

Molecular Formula
CH3NaO
Molar Mass
54.02 g/mol
IUPAC Name
sodium methanolate

Chemical Identifiers

InChI
InChI=1S/CH3O.Na/c1-2;/h1H3;/q-1;+1
InChI Key
WQDUMFSSJAZKTM-UHFFFAOYSA-N

Overview

Sodium methanolate (CAS 124-41-4) is an alkali metal alkoxide compound with strong basic properties and high reactivity toward moisture. Sodium methanolate, also known as sodium methoxide, represents a crucial organometallic reagent widely utilized in industrial chemistry and organic synthesis. This white to slightly yellowish crystalline solid serves as one of the most important alkoxide bases, functioning primarily as a strong nucleophile and base in various chemical transformations. The compound's molecular structure consists of a sodium cation bonded to a methoxide anion, resulting in its characteristic high reactivity and moisture sensitivity. The substance exhibits significant safety considerations due to its corrosive nature and self-heating properties, classified under GHS02 and GHS05 pictograms with a "Danger" signal word. Its ADR classification as Class 4.2 reflects its potential for spontaneous combustion when exposed to air or moisture. Like other organometallic compounds such as tripropylalumane and lithium hexane, sodium methanolate requires careful handling under inert atmosphere conditions to prevent unwanted reactions with atmospheric moisture or oxygen. In industrial applications, sodium methanolate serves primarily as a catalyst in biodiesel production through transesterification reactions, converting vegetable oils and animal fats into methyl esters. The compound also finds extensive use in pharmaceutical manufacturing as a base for various organic syntheses and in the production of specialty chemicals where strong basic conditions are required. Additionally, it functions as an important intermediate in the synthesis of other sodium-based reagents and organic compounds. OYSI provides high-quality sodium methanolate to meet diverse industrial requirements across European markets, supporting customers with technical expertise and reliable supply chain management.

Safety & Classification

Danger
Classification:

Self-heat. 1; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1431
ADR Class4.2
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameNatriummethylat, fest
Marine PollutantNo

Frequently Asked Questions

What is sodium methanolate?

Sodium methanolate is a chemical compound with the formula CH3NaO and CAS number 124-41-4. It is the sodium salt of methanol, also known as sodium methoxide. With a molecular weight of 54.024 g/mol, this substance is classified as a self-heating material and skin corrosive compound. It appears as a white to off-white powder or crystalline solid and is highly reactive with water and moisture.

What are the physico-chemical properties of sodium methanolate?

Sodium methanolate is a white to off-white crystalline powder or solid at room temperature. It is highly hygroscopic and readily absorbs moisture from air. The compound is highly soluble in methanol and reacts vigorously with water, producing methanol and sodium hydroxide. It has self-heating properties and can ignite spontaneously when exposed to air or moisture, making it thermally unstable under normal atmospheric conditions.

What is sodium methanolate used for?

Sodium methanolate is primarily used as a strong base and nucleophile in organic synthesis reactions. It serves as a catalyst in transesterification processes, particularly in biodiesel production from vegetable oils. The compound is also utilized in pharmaceutical manufacturing, polymer synthesis, and as a condensation agent in various chemical processes. Additionally, it finds applications in the production of other sodium salts and as a deprotonating agent in organic chemistry.

How to handle sodium methanolate safely?

Sodium methanolate must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its corrosive nature. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid contact with water, moisture, and incompatible materials. Use non-sparking tools and ensure proper grounding to prevent static electricity buildup, as the substance has self-heating properties and fire hazards.

How to store sodium methanolate correctly?

Sodium methanolate should be stored in tightly sealed, moisture-proof containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers away from water, acids, and oxidizing agents to prevent dangerous reactions. Storage areas should be equipped with appropriate fire suppression systems and maintained at stable temperatures. Containers must be properly labeled and stored according to ADR Class 4.2 requirements for self-heating substances.

What to do in case of contact with sodium methanolate?

Immediate medical attention is required for any contact with sodium methanolate due to its corrosive properties. For skin contact, immediately remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes. In case of eye contact, flush thoroughly with water and seek immediate medical care. If inhaled, move the person to fresh air and provide respiratory support if needed. Never induce vomiting if ingested.

How to dispose of sodium methanolate appropriately?

Sodium methanolate disposal must comply with local and national hazardous waste regulations as it is classified as dangerous goods. The substance should be neutralized carefully by qualified personnel before disposal, typically by controlled reaction with appropriate solvents under controlled conditions. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this material in regular waste streams or pour down drains due to its reactive and corrosive nature.

How to transport sodium methanolate?

Sodium methanolate is classified under ADR Class 4.2 (substances liable to spontaneous combustion) with Packing Group II, indicating moderate danger level. Transportation requires appropriate packaging, labeling with GHS02 and GHS05 pictogrammes, and proper documentation. Vehicles must comply with ADR regulations for Class 4.2 materials, including appropriate fire suppression equipment. Drivers need ADR certification, and transport should avoid extreme temperatures and moisture exposure during transit.

Is sodium methanolate subject to particular regulations?

Sodium methanolate is subject to various chemical safety regulations including REACH registration requirements in Europe and CLP classification as Self-heating Category 1 and Skin Corrosive 1B. It requires safety data sheets and proper hazard communication with danger signal word and specific pictogrammes. The substance is not listed as SVHC (Substance of Very High Concern), but strict handling, storage, and transport regulations apply due to its hazardous classification and reactive properties.

Where to buy sodium methanolate in Europe?

Sodium methanolate is available through OYSI, a European distributor of technical chemicals specializing in quality chemical products. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance. As a specialized chemical distributor, OYSI ensures product quality, appropriate packaging, and technical support for industrial customers requiring sodium methanolate for their manufacturing processes and chemical applications throughout European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.