Propan-2-yl 2-chloroacetate

Propan-2-yl 2-chloroacetate is an organic chemical compound with the molecular formula C5H9ClO2 and CAS number 105-48-6. It belongs to the family of chloroacetate esters, featuring a chloroacetyl group attached to an isopropyl alcohol moiety. With a molecular weight of 136.58 g/mol, this compound is classified as a hazardous substance requiring careful handling due to its flammability and toxicity properties.

Propan-2-yl 2-chloroacetate is typically a colorless to pale yellow liquid at room temperature with a characteristic ester odor. As an organic ester compound, it exhibits limited solubility in water but readily dissolves in organic solvents such as alcohols, ethers, and hydrocarbons. The compound's physical properties are influenced by both its ester functionality and the presence of the chlorine atom in its structure.

Propan-2-yl 2-chloroacetate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for the production of various chemical compounds, particularly in the synthesis of active pharmaceutical ingredients and agrochemicals. The compound's reactive chloroacetyl group makes it valuable for alkylation reactions and as a precursor in the preparation of more complex molecular structures in fine chemical production.

Propan-2-yl 2-chloroacetate requires careful handling due to its classification as Acute Tox. 3, Skin Irrit. 2, and Eye Irrit. 2. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from ignition sources as it's classified as Flam. Liq. 3, and avoid direct skin or eye contact to prevent irritation and potential toxic effects.

Propan-2-yl 2-chloroacetate should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable nature. Keep containers tightly sealed to prevent contamination and evaporation. Store away from incompatible materials such as strong bases, oxidizing agents, and reactive metals. Maintain storage temperatures below 25°C and ensure proper secondary containment to prevent environmental release in case of container failure.

In case of skin contact with propan-2-yl 2-chloroacetate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist or worsen.

Propan-2-yl 2-chloroacetate must be disposed of as hazardous waste in accordance with local, national, and EU regulations. Do not discharge into drains, waterways, or soil. Contact licensed waste management companies for proper collection and treatment. The compound should be incinerated at high temperatures in approved facilities equipped with appropriate emission control systems. Always consult current waste classification codes and disposal requirements in your specific jurisdiction before disposal.

Propan-2-yl 2-chloroacetate is classified under ADR Class 3 (Flammable Liquids), Packing Group III for transportation purposes. It must be packaged in UN-approved containers and properly labeled with appropriate hazard markings and transport documentation. Vehicles must comply with ADR requirements for Class 3 substances, including proper ventilation and fire safety equipment. Drivers require ADR certification, and transport must follow designated routes with appropriate emergency response procedures in place.

Propan-2-yl 2-chloroacetate is subject to various EU regulations including REACH registration requirements and CLP classification as a hazardous substance. It is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with occupational safety regulations, environmental protection laws, and transport regulations (ADR). Users must maintain safety data sheets, conduct risk assessments, and implement appropriate risk management measures as required by current legislation.

Propan-2-yl 2-chloroacetate is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides this compound to industrial customers, research institutions, and pharmaceutical companies across Europe. As a professional chemical distributor, OYSI ensures proper documentation, regulatory compliance, and technical support for customers requiring this specialized chemical intermediate. Contact OYSI directly for availability, specifications, and delivery options in your region.