(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide

C8H10ClN5O3S

CAS153719-23-4
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

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Identification

CAS Number
153719-23-4
EC Number
428-650-4
UN Number
3077
Index Number
613-267-00-9
PubChem CID
5821911

Physical-chemical properties

Molecular Formula
C8H10ClN5O3S
Molar Mass
291.72 g/mol
IUPAC Name
(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide

Chemical Identifiers

InChI
InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+
InChI Key
NWWZPOKUUAIXIW-DHZHZOJOSA-N

Overview

(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide (CAS 153719-23-4) is a neonicotinoid insecticide with systemic activity and broad-spectrum efficacy against sucking insects. This synthetic compound belongs to the neonicotinoid class of insecticides, characterized by its unique oxadiazinane ring structure combined with a chlorothiazole moiety. With a molecular formula of C8H10ClN5O3S and molecular weight of 291.72 g/mol, this substance demonstrates selective toxicity towards insect nicotinic acetylcholine receptors while showing reduced mammalian toxicity compared to organophosphate alternatives. The molecule's structural design allows for excellent systemic translocation in plants, providing both contact and residual control against target pests. The compound exhibits significant safety considerations, classified under GHS with Warning signal word and displaying pictograms GHS08, GHS07, and GHS09, indicating health hazards and environmental concerns. Its classification includes Reproductive toxicity Category 2, Acute toxicity Category 4, and Aquatic toxicity (both acute and chronic Category 1), requiring careful handling protocols and environmental risk assessment. Transportation falls under ADR Class 9 miscellaneous dangerous substances. Primary industrial applications include crop protection formulations for agricultural use, particularly in integrated pest management systems targeting aphids, whiteflies, and thrips. The compound is also utilized in specialty formulations for greenhouse applications and as an active ingredient in professional pest control products. Its systemic properties make it valuable for seed treatment applications, similar to how other neonicotinoids function in agricultural settings. OYSI provides this technical-grade compound to qualified industrial customers across Europe, supporting formulation development and agricultural chemistry applications with comprehensive regulatory documentation and technical support.

Safety & Classification

Warning
Classification:

Repr. 2; Acute Tox. 4; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameThiamethoxam (ISO)
Marine PollutantNo

Frequently Asked Questions

What is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide is a synthetic chemical compound with CAS number 153719-23-4 and molecular formula C8H10ClN5O3S. This complex organic molecule contains thiazole and oxadiazinane ring systems with a nitramide functional group. With a molecular weight of 291.72 g/mol, it belongs to the class of heterocyclic compounds featuring chlorine, nitrogen, oxygen, and sulfur atoms in its structure.

What are the physicochemical properties of (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

The compound is a solid substance at room temperature with a molecular weight of 291.72 g/mol and chemical formula C8H10ClN5O3S. Its structure contains multiple heteroatoms including chlorine, nitrogen, oxygen, and sulfur, which influence its polarity and solubility characteristics. The presence of the thiazole ring and nitramide group contributes to its stability profile. Specific physical properties such as melting point, boiling point, and exact solubility data require detailed analytical characterization.

What is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide used for?

This compound is primarily used as an active ingredient in agricultural applications, particularly as an insecticide. The thiazole-oxadiazinane structure with nitramide functionality provides biological activity against target pest species. It is employed in crop protection formulations for agricultural and horticultural use. The compound may also serve as an intermediate in the synthesis of related agrochemical products. Its specific mode of action and target spectrum make it valuable for integrated pest management programs.

How to handle (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide safely?

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 4 and Repr. 2 classifications. Work in well-ventilated areas or under fume extraction to minimize inhalation exposure. Avoid direct skin and eye contact, and prevent ingestion. Use proper handling techniques to minimize dust generation and implement containment measures. Regular safety training and adherence to safety data sheet recommendations are essential for worker protection.

How to store (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide correctly?

The compound should be stored in a cool, dry, well-ventilated area away from incompatible materials and ignition sources. Use original containers or approved chemical storage containers with proper labeling. Maintain storage temperatures within recommended ranges and protect from moisture, direct sunlight, and extreme temperatures. Implement appropriate containment measures to prevent environmental release given its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Regular inventory checks and proper segregation from incompatible chemicals are essential.

What to do in case of contact with (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

In case of skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms develop or persist, and provide the safety data sheet to medical personnel.

How to dispose of (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide properly?

Disposal must be conducted according to local, national, and international regulations for hazardous chemical waste. The compound cannot be disposed of in regular waste streams due to its hazard classifications. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Incineration at approved high-temperature facilities may be appropriate under controlled conditions. Empty containers should also be handled as hazardous waste. Documentation of disposal activities is typically required for regulatory compliance.

How to transport (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

The compound is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation requirements according to international dangerous goods regulations. Use UN-approved packaging materials and ensure proper hazard labels and placarding. Transport vehicles must comply with ADR requirements including equipment and driver training. Shipping papers must include proper shipping names, hazard classes, and emergency response information.

Is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide subject to special regulations?

Yes, the compound is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification regulations. It requires proper hazard classification with Warning signal word and specific GHS pictograms (GHS07, GHS08, GHS09). While not identified as an SVHC substance, its reproductive toxicity (Repr. 2) and aquatic toxicity classifications trigger specific regulatory obligations. Biocidal product regulations may also apply depending on intended use. Import/export restrictions may apply in certain jurisdictions.

Where to buy (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide in Europe?

OYSI serves as a reliable European distributor for this specialized chemical compound, providing access to qualified industrial and research customers. As a professional chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for hazardous materials. The compound is available for legitimate applications including research, development, and industrial use. Contact OYSI directly for availability, technical specifications, safety documentation, and regulatory support throughout Europe. Proper customer qualification and end-use documentation are required for purchase.

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(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.