(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide

C8H10ClN5O3S

CAS153719-23-4
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

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Identification

CAS Number
153719-23-4
EC Number
428-650-4
UN Number
3077
Index Number
613-267-00-9
PubChem CID
5821911

Physical-chemical properties

Molecular Formula
C8H10ClN5O3S
Molar Mass
291.72 g/mol
IUPAC Name
(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide

Chemical Identifiers

InChI
InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+
InChI Key
NWWZPOKUUAIXIW-DHZHZOJOSA-N

Overview

(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide (CAS 153719-23-4) is a specialized neonicotinoid insecticide with systemic activity and broad-spectrum pest control properties. This complex heterocyclic compound, with molecular formula C8H10ClN5O3S and molecular weight 291.72 g/mol, belongs to the neonicotinoid class of insecticides that act on the central nervous system of insects by binding to nicotinic acetylcholine receptors. The compound features a distinctive thiazole ring system combined with an oxadiazinan structure, providing its characteristic insecticidal properties and systemic translocation capabilities within plant tissues. The substance presents significant safety considerations, classified under multiple hazard categories including reproductive toxicity (Repr. 2), acute toxicity (Acute Tox. 4), and severe aquatic environmental hazards (Aquatic Acute 1; Aquatic Chronic 1). The ADR Class 9 classification requires specialized handling and transport protocols. Safety pictograms GHS08, GHS07, and GHS09 indicate health hazards, acute toxicity, and environmental dangers respectively, necessitating comprehensive risk management procedures during industrial handling. Primary industrial applications include crop protection formulations for agricultural use, particularly in integrated pest management systems where systemic insecticidal activity is required. The compound is also utilized in specialized pest control products for horticultural applications and as an active ingredient in professional-grade insecticide formulations. Unlike structurally different compounds such as 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol, this neonicotinoid offers specific advantages in terms of systemic distribution and target selectivity. OYSI provides this technical-grade compound to qualified industrial customers with comprehensive documentation including safety data sheets, certificates of analysis, and regulatory compliance information for European markets.

Safety & Classification

Warning
Classification:

Repr. 2; Acute Tox. 4; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameThiamethoxam (ISO)
Marine PollutantNo

Frequently Asked Questions

What is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide is a synthetic organic compound with the molecular formula C8H10ClN5O3S and CAS number 153719-23-4. This complex heterocyclic molecule contains thiazole and oxadiazinane rings with a nitramide functional group. With a molecular weight of 291.72 g/mol, it is classified as a hazardous substance requiring careful handling due to its reproductive toxicity and aquatic environmental risks.

What are the physicochemical properties of (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

The compound is a solid organic material at room temperature with specific physicochemical characteristics typical of nitrogen-containing heterocycles. Its molecular structure includes chlorine, sulfur, nitrogen, and oxygen atoms contributing to its unique properties. The presence of thiazole and oxadiazinane rings influences its stability and reactivity. Detailed physical properties such as melting point, boiling point, and solubility data should be obtained from the manufacturer's technical specifications for precise handling requirements.

What is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide used for?

This compound is primarily used as an active ingredient in agricultural applications, particularly as an insecticide. Its complex molecular structure containing thiazole and nitramide groups provides specific biological activity against target pests. The substance is utilized in crop protection formulations and integrated pest management systems. Professional applications require specialized knowledge and appropriate licensing due to its classification as a reproductive toxicant and environmental hazard to aquatic organisms.

How to handle (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide safely?

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, protective clothing, and eye protection due to its Acute Tox. 4 and Repr. 2 classifications. Work in well-ventilated areas or use local exhaust ventilation to minimize exposure. Avoid skin contact, inhalation, and ingestion. Pregnant women should avoid handling this substance due to reproductive toxicity concerns. Follow strict hygiene measures including thorough hand washing after use and before eating or drinking.

How to store (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide correctly?

Store the compound in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly sealed and properly labeled with hazard information. Storage areas should be equipped with appropriate spill containment measures due to its aquatic toxicity. Maintain storage temperatures according to manufacturer specifications and ensure access is restricted to authorized personnel only. Regular inventory checks and proper segregation from other chemicals are essential.

What to do in case of contact with (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

Immediate first aid measures include removing contaminated clothing and rinsing affected skin with plenty of water for at least 15 minutes. In case of eye contact, flush thoroughly with clean water and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek immediate medical care. Always consult the safety data sheet for specific emergency procedures and contact poison control if necessary.

How to dispose of (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide appropriately?

Disposal must comply with local, national, and European waste regulations due to its hazardous classification and environmental risks to aquatic life. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance through regular waste streams, sewerage systems, or into the environment. Empty containers should also be treated as hazardous waste. Maintain proper documentation of disposal activities and ensure compliance with REACH and waste framework directive requirements.

How to transport (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide?

The compound is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. Proper shipping documentation, hazard labels, and UN packaging specifications must be followed. Vehicles must carry appropriate emergency equipment and drivers need ADR training certification. Ensure packages are properly sealed, labeled with correct hazard pictograms, and accompanied by transport emergency cards. Comply with quantity limitations and routing restrictions for dangerous goods transportation within Europe.

Is (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide subject to specific regulations?

The substance is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as a SVHC (Substance of Very High Concern), its reproductive toxicity classification may trigger additional regulatory scrutiny. Biocide and plant protection product regulations may apply depending on intended use. Companies must maintain safety data sheets, implement risk management measures, and comply with notification requirements for professional users and downstream applications.

Where to buy (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide in Europe?

OYSI serves as a reliable European distributor for this specialized chemical compound, offering professional supply services to qualified industrial customers. Our distribution network ensures compliance with European chemical regulations and proper handling throughout the supply chain. We provide technical support, regulatory documentation, and appropriate packaging for safe delivery. Contact our technical sales team for availability, specifications, and regulatory requirements specific to your application and jurisdiction within Europe.

Services for (NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide

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(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-ylidene]nitramide is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.