(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide
C9H10ClN5O2
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Identification
- CAS Number
- 138261-41-3
- EC Number
- 428-040-8
- UN Number
- 3077
- Index Number
- 612-252-00-4
- PubChem CID
- 86287518
Physical-chemical properties
- Molecular Formula
- C9H10ClN5O2
- Molar Mass
- 255.66 g/mol
- IUPAC Name
- (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide
Chemical Identifiers
- InChI
- InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)
- InChI Key
- YWTYJOPNNQFBPC-UHFFFAOYSA-N
Overview
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide (CAS 138261-41-3) is a neonicotinoid insecticide compound with selective neurotoxic properties against insect nicotinic acetylcholine receptors. This chlorinated pyridine derivative, with molecular formula C9H10ClN5O2 and molecular weight 255.66 g/mol, belongs to the neonicotinoid family of synthetic insecticides that revolutionized pest control in agriculture and veterinary applications. The compound features a characteristic imidazolidin-2-ylidene core structure linked to a chloropyridinyl moiety, which confers its selective binding affinity to insect nicotinic receptors while showing reduced mammalian toxicity compared to organophosphate alternatives. The substance exhibits significant environmental persistence and bioaccumulation potential, reflected in its Aquatic Acute 1 and Aquatic Chronic 1 classifications under GHS. Its Acute Tox. 3 rating and associated GHS06 and GHS09 pictograms indicate both human health hazards and environmental risks requiring careful handling protocols. Transportation falls under ADR Class 9 miscellaneous dangerous goods, necessitating specialized logistics considerations. Primary industrial applications include formulation into crop protection products for agricultural use, integration into veterinary flea and tick control treatments, and incorporation into professional pest management solutions. Unlike structurally different compounds such as 2-(trichloromethylsulfanyl)isoindole-1,3-dione, this neonicotinoid operates through specific neuroreceptor antagonism rather than broad cellular disruption mechanisms. The compound requires specialized storage conditions and regulatory compliance documentation due to its environmental classification and biocidal properties. OYSI maintains technical-grade supplies of this specialized insecticidal intermediate for qualified industrial customers requiring documented pest control formulation components.
Safety & Classification
Acute Tox. 3; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | Imidacloprid (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide is a synthetic organic compound with the molecular formula C9H10ClN5O2 and CAS number 138261-41-3. This chemical substance has a molecular weight of 255.66 g/mol and contains chloropyridinyl and imidazolidine functional groups linked to a nitramide moiety. It is classified as acutely toxic and presents significant environmental hazards to aquatic ecosystems, requiring careful handling and disposal procedures.
What are the physicochemical properties of (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide exhibits specific physicochemical characteristics typical of chlorinated pyridine derivatives. The compound has a molecular weight of 255.66 g/mol and contains nitrogen-rich functional groups. As with most nitramide compounds, it likely exists as a crystalline solid at room temperature. Detailed physical properties such as melting point, solubility, and appearance should be confirmed through technical data sheets from suppliers.
What is (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide used for?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide serves as an important intermediate in pharmaceutical and agrochemical synthesis. The compound's unique structural features, including the chloropyridinyl and nitramide groups, make it valuable for developing specialized chemical products. It may be used in research applications for medicinal chemistry or as a building block for more complex molecular structures. Industrial applications typically involve controlled synthetic processes requiring specialized handling protocols.
How to handle (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide safely?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide requires strict safety protocols due to its Acute Tox. 3 classification and Danger signal word. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact and ingestion, and ensure emergency procedures are readily available before handling this hazardous substance.
How to store (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide correctly?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from incompatible materials. Given its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), storage areas must have appropriate containment measures to prevent environmental release. Keep containers properly labeled and store away from heat sources, oxidizing agents, and reactive chemicals. Access should be restricted to trained personnel only.
What to do in case of contact with (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide?
Immediate action is required following contact with (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide due to its acute toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. In case of eye contact, flush with clean water for 15 minutes and remove contact lenses if present. For ingestion, do not induce vomiting and seek immediate medical attention.
How to dispose of (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide appropriately?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide requires specialized disposal procedures due to its environmental hazard classification. The substance must be disposed of through licensed hazardous waste disposal facilities in accordance with local and EU waste regulations. It cannot be discharged into sewers, water bodies, or soil due to its aquatic toxicity. Contaminated packaging should also be treated as hazardous waste and disposed of through appropriate channels following regulatory requirements.
How to transport (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. This classification requires specific packaging, labeling, and documentation for road transport within Europe. Shipments must comply with ADR regulations including proper packaging specifications, hazard labels, and transport documentation. Only authorized carriers with appropriate permits should handle the transportation of this regulated chemical substance.
Is (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide subject to particular regulations?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide is subject to European REACH and CLP regulations due to its hazardous properties. While not currently listed as a Substance of Very High Concern (SVHC), it must comply with standard chemical safety requirements including proper classification, labeling, and safety data sheet provisions. Companies handling this substance must ensure compliance with occupational safety regulations and environmental protection requirements throughout the EU.
Where to buy (NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide in Europe?
(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide is available through specialized chemical distributors across Europe. OYSI, as a leading European chemical distributor, can provide this compound to qualified industrial and research customers with appropriate handling capabilities. Procurement requires compliance with regulatory requirements and proper safety protocols. Customers should contact OYSI directly to discuss availability, specifications, and regulatory documentation needed for this controlled chemical substance.
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(NE)-N-[1-[(6-chloro-3-pyridinyl)methyl]imidazolidin-2-ylidene]nitramide is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.