4,5,6,7-tetrachloro-2-benzofuran-1,3-dione

C8Cl4O3

CAS117-08-8
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
117-08-8
EC Number
204-171-4
UN Number
3077
Index Number
607-242-00-1
PubChem CID
8326

Physical-chemical properties

Molecular Formula
C8Cl4O3
Molar Mass
285.90 g/mol
IUPAC Name
4,5,6,7-tetrachloro-2-benzofuran-1,3-dione

Chemical Identifiers

InChI
InChI=1S/C8Cl4O3/c9-3-1-2(8(14)15-7(1)13)4(10)6(12)5(3)11
InChI Key
AUHHYELHRWCWEZ-UHFFFAOYSA-N

Overview

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione (CAS 117-08-8) is a chlorinated aromatic anhydride compound with high reactivity and strong electrophilic properties. This tetrachlorinated benzofuran derivative represents a significant industrial intermediate in organic synthesis applications. With its molecular formula C8Cl4O3 and molecular weight of 285.9 g/mol, this compound exhibits the characteristic reactivity of anhydride functional groups combined with the enhanced electrophilicity conferred by four chlorine substituents on the benzene ring. The extensive chlorination pattern makes it particularly valuable for specialized chemical transformations where high reactivity is required. The compound presents notable safety considerations due to its classification as Eye Dam. 1, Resp. Sens. 1, and Skin Sens. 1, requiring appropriate handling protocols and personal protective equipment. Its environmental classification as Aquatic Acute 1 and Aquatic Chronic 1 indicates significant aquatic toxicity, necessitating careful containment and disposal procedures. The GHS05, GHS08, and GHS09 pictograms reflect its corrosive nature, health hazards, and environmental dangers respectively. Primary industrial applications include its use as an intermediate in pharmaceutical synthesis, particularly for compounds requiring chlorinated aromatic frameworks, and as a reagent in specialized polymer chemistry. Unlike simpler compounds such as benzene-1,4-diol which serves as a basic building block, this tetrachlorinated anhydride offers unique reactivity patterns essential for complex synthetic pathways. It also finds application in the production of specialty dyes and pigments where the chlorinated structure provides specific color properties and chemical stability. The compound is classified under ADR Class 9 for transportation purposes, reflecting its miscellaneous dangerous goods status. OYSI maintains reliable supply chains for this specialized chemical intermediate to support European industrial applications.

Safety & Classification

Danger
Classification:

Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H318

Causes serious eye damage.

H334

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameTetrachlorphthalsäureanhydrid
Marine PollutantNo

Frequently Asked Questions

What is 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is a chlorinated organic compound with the molecular formula C8Cl4O3 and CAS number 117-08-8. This chemical belongs to the benzofuran family and contains four chlorine atoms, giving it a molecular weight of 285.9 g/mol. It is classified as a hazardous substance requiring careful handling due to its potential health and environmental impacts.

What are the physicochemical properties of 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is a solid organic compound with a molecular weight of 285.9 g/mol. As a highly chlorinated benzofuran derivative, it typically appears as a crystalline solid at room temperature. The presence of four chlorine atoms and the benzofuran structure influence its solubility characteristics and chemical stability, making it relatively persistent in environmental conditions.

What is 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione used for?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is primarily used as an intermediate in chemical synthesis and pharmaceutical manufacturing. Its chlorinated benzofuran structure makes it valuable for developing specialty chemicals, agrochemicals, and pharmaceutical compounds. Due to its specific molecular structure, it serves as a building block in organic synthesis processes requiring chlorinated aromatic compounds with particular reactivity patterns.

How to handle 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione safely?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione requires strict safety measures due to its classification as Eye Dam. 1, Resp. Sens. 1, and Skin Sens. 1. Use appropriate respiratory protection, chemical-resistant gloves, and eye protection. Work in well-ventilated areas or under fume hoods. Avoid skin and eye contact, and prevent inhalation of dust or vapors. Follow GHS safety pictograms GHS05, GHS08, and GHS09 guidelines.

How to store 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione correctly?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep away from heat sources, ignition sources, and direct sunlight. Store separately from strong bases, reducing agents, and reactive metals. Ensure proper labeling with hazard pictograms and maintain controlled access due to its hazardous classification.

What to do in case of contact with 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione?

Immediate action is required for 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione contact due to its Eye Dam. 1 and Skin Sens. 1 classifications. For eye contact, flush immediately with water for at least 15 minutes and seek medical attention. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. If inhaled, move to fresh air immediately. Seek medical attention for all exposures due to respiratory sensitization potential.

How to dispose of 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione properly?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione must be disposed of as hazardous waste according to local and European regulations. Contact licensed hazardous waste disposal companies for proper treatment. Due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications, prevent release to water systems. Incineration at appropriate temperatures in licensed facilities is typically the preferred disposal method for chlorinated organic compounds.

How to transport 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is classified as ADR Class 9, Packing Group III for transportation. This classification indicates it's a miscellaneous dangerous substance requiring appropriate packaging, labeling, and documentation. Use UN-approved packaging and ensure proper hazard labels are displayed. Transport vehicles must comply with ADR regulations, and drivers need appropriate training for Class 9 dangerous goods transportation.

Is 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione subject to specific regulations?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is subject to REACH and CLP regulations in Europe, requiring proper registration, classification, and safety data sheet provision. While not currently listed as SVHC, its multiple hazard classifications (Eye Dam. 1, Resp. Sens. 1, Skin Sens. 1, Aquatic hazards) mandate strict compliance with occupational health and environmental protection requirements across EU member states.

Where to buy 4,5,6,7-tetrachloro-2-benzofuran-1,3-dione in Europe?

4,5,6,7-tetrachloro-2-benzofuran-1,3-dione is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to industrial and research customers across Europe, ensuring full regulatory compliance including proper documentation, safety data sheets, and appropriate packaging. Contact OYSI directly for availability, technical specifications, and regulatory support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.