Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is a complex organic compound with CAS number 131860-33-8 and molecular formula C22H17N3O5. This substance has a molecular weight of 403.4 g/mol and features a sophisticated chemical structure containing pyrimidine, phenoxy, and methoxypropenoate functional groups. It is classified as a hazardous substance with acute toxicity properties and environmental risks, requiring careful handling and storage procedures in industrial applications.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is an organic solid compound with a molecular weight of 403.4 g/mol. The substance contains multiple aromatic rings and polar functional groups, which influence its solubility characteristics. Its complex structure with ester, ether, nitrile, and pyrimidine functionalities determines its chemical stability and reactivity profile. Specific physical properties such as melting point, boiling point, and exact solubility data would require detailed technical specifications from the manufacturer.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its complex structure featuring pyrimidine and phenoxy groups makes it valuable for developing bioactive compounds. The substance serves as a building block in organic synthesis for creating specialized molecules with potential biological activity. Industrial applications typically involve controlled synthesis processes in research laboratories and manufacturing facilities specializing in fine chemicals and active pharmaceutical ingredients.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate requires careful handling due to its Acute Tox. 3 classification and environmental hazards. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection when handling powders or during synthesis. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Implement proper hygiene measures including handwashing after handling and removal of contaminated clothing before leaving work areas.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), prevent release to the environment and ensure secondary containment. Store away from heat sources, direct sunlight, and moisture. Keep containers properly labeled and segregated from food, feed, and drinking water. Regular inventory checks should be performed to monitor container integrity and substance condition.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate exposure requires immediate first aid measures due to its acute toxicity. For skin contact, remove contaminated clothing and rinse with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult emergency services and provide the safety data sheet to medical personnel.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate must be disposed of through licensed hazardous waste management companies due to its toxicity and environmental hazard classifications. The substance cannot be discharged to sewers, water bodies, or soil due to its aquatic toxicity. Contaminated packaging should be treated as hazardous waste. Follow local and national regulations for hazardous chemical disposal, including proper waste classification codes. Incineration at high temperatures in approved facilities may be required, ensuring complete destruction and appropriate emission controls.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is classified as ADR Class 6.1 (toxic substances), Packing Group III, requiring compliance with dangerous goods transportation regulations. Packages must be properly labeled with GHS06 and GHS09 pictograms and appropriate hazard warnings. Vehicles must carry emergency response information and drivers require dangerous goods training certification. Transportation documentation must include proper shipping names, UN numbers, and emergency contact information. Ensure secure packaging to prevent leakage and environmental contamination during transit.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is subject to REACH regulation for registration, evaluation, and authorization of chemicals in the European Union, though it is not currently listed as a Substance of Very High Concern (SVHC). The substance must comply with CLP regulation for classification, labeling, and packaging as indicated by its GHS pictograms and hazard statements. Additional restrictions may apply for specific uses, and national regulations for toxic substances and environmental protection must be observed across different European countries.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable sourcing of complex organic compounds with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures quality control, appropriate packaging, and adherence to transportation regulations for hazardous materials. Contact OYSI directly for availability, technical specifications, and purchasing requirements for this specialized chemical intermediate.