Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is a complex organic compound with CAS number 131860-33-8 and molecular formula C22H17N3O5. This substance has a molecular weight of 403.4 g/mol and features a sophisticated structure containing pyrimidine, phenoxy, and methacrylate functional groups. It is classified as a hazardous chemical with acute toxicity and environmental hazard properties, requiring careful handling and specialized safety measures.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is a solid organic compound at room temperature with a molecular weight of 403.4 g/mol. The substance contains multiple aromatic rings and functional groups including nitrile, ether, and ester moieties. Its complex structure suggests limited water solubility but potential solubility in organic solvents. Specific physical properties such as melting point, density, and exact solubility parameters should be confirmed through technical documentation.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its complex structure containing pyrimidine and phenoxy groups makes it valuable for developing bioactive compounds. The substance may serve as a building block in the production of specialized chemicals, research applications, or as a precursor in multi-step synthetic processes requiring precise molecular architecture.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate requires strict safety precautions due to its Acute Tox. 3 classification. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume extraction systems. Avoid skin and eye contact, inhalation, and ingestion. Implement proper hygiene measures including hand washing and contaminated clothing removal. Emergency procedures and safety data sheets must be readily accessible to all handlers.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed original containers in designated chemical storage areas with appropriate secondary containment. Due to its environmental hazard classification, prevent release to soil and water systems. Implement temperature control and moisture protection measures. Maintain proper inventory management and ensure storage areas meet local regulatory requirements for toxic substances.

Immediate first aid measures are critical due to the acute toxicity of this substance. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult poison control or emergency medical services while providing the safety data sheet.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate requires disposal as hazardous waste through licensed waste management facilities. Due to its acute toxicity and environmental hazard classification, it cannot be disposed of in regular waste streams or released to sewers or environment. Contact certified hazardous waste disposal companies for proper treatment methods such as high-temperature incineration. Maintain disposal documentation and comply with local, national, and EU waste regulations including the Waste Framework Directive.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is classified as ADR Class 6.1 (toxic substances), Packing Group III. Transport requires appropriate dangerous goods packaging, labeling with GHS06 and GHS09 pictograms, and proper shipping documentation. Vehicles must carry emergency response information and drivers need ADR certification. Packaging must meet UN specifications for toxic substances and prevent environmental release. Consult current ADR regulations for specific packaging instructions and transport requirements.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is subject to EU REACH regulation requiring registration for commercial use. The substance is classified under CLP Regulation with GHS06 and GHS09 pictograms, requiring appropriate labeling and safety data sheets. It is not currently listed as an SVHC (Substance of Very High Concern). Companies must comply with occupational safety regulations, environmental protection laws, and transport regulations (ADR Class 6.1) throughout the supply chain.

Methyl (E)-2-[2-[6-(2-cyanophenoxy)pyrimidin-4-yl]oxyphenyl]-3-methoxyprop-2-enoate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides professional-grade chemicals to research institutions, pharmaceutical companies, and industrial customers across Europe. As a specialized substance requiring expert handling, it is typically available through established chemical supply networks rather than general suppliers. Contact OYSI directly for availability, specifications, documentation, and technical support to ensure compliance with safety and regulatory requirements.