N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is an organic compound with the molecular formula C15H17NO3S and CAS number 149118-66-1. This chemical substance has a molecular weight of 291.4 g/mol and belongs to the benzothiophene carboxamide family. It is classified as hazardous due to its acute toxicity, severe eye damage potential, and aquatic toxicity properties, requiring careful handling and appropriate safety measures in industrial applications.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is a solid organic compound at room temperature with a molecular weight of 291.4 g/mol. The molecule contains a benzothiophene ring system with a sulfonyl group and a cyclohexyl carboxamide substituent. Its chemical structure suggests limited water solubility due to the hydrophobic cyclohexyl and aromatic components, while the amide and sulfonyl groups provide some polar character to the molecule.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its benzothiophene structure makes it valuable for developing bioactive compounds and pharmaceutical intermediates. The compound may also serve as a research chemical in academic and industrial laboratories for synthetic chemistry applications and structure-activity relationship studies in drug discovery programs.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide requires careful handling due to its acute toxicity and severe eye damage potential. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Use appropriate engineering controls and ensure emergency eyewash stations are readily accessible.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and protected from physical damage. Storage areas should be equipped with appropriate spill control measures and restricted to authorized personnel only. Maintain proper labeling and safety data sheets accessible. Regular inventory checks ensure container integrity and proper storage conditions.

Immediate first aid is crucial for N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide exposure. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention due to severe eye damage potential. For skin contact, wash thoroughly with soap and water. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a poison control center or physician for specific medical advice.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide disposal must comply with local and national hazardous waste regulations due to its toxicity and environmental impact. The substance should be collected as hazardous chemical waste and disposed of through licensed waste management facilities. Incineration at appropriate high-temperature facilities is typically the preferred method. Never dispose of in regular trash, sewers, or waterways due to its aquatic toxicity classification.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. Packaging must comply with UN specifications and proper hazard labels must be affixed. Transport documents must include the correct shipping name and UN number. Vehicles must carry appropriate emergency equipment and drivers require proper training for hazardous materials transport according to ADR regulations.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is subject to REACH regulation in Europe and must comply with CLP classification requirements. It is classified under multiple hazard categories including acute toxicity, serious eye damage, and aquatic toxicity. The substance is not currently listed as SVHC (Substance of Very High Concern). Users must ensure proper registration, safety data sheet availability, and compliance with occupational exposure limits and environmental protection measures.

N-cyclohexyl-1,1-dioxo-1-benzothiophene-2-carboxamide is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with complete regulatory documentation including safety data sheets and certificates of analysis. As a professional chemical supplier, OYSI ensures proper packaging, labeling, and compliance with European chemical regulations for safe delivery to qualified industrial and research customers across Europe.