N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide
C14H14ClNO3
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Identification
- CAS Number
- 69581-33-5
- EC Number
- 274-050-9
- UN Number
- 2761
- Index Number
- 616-033-00-4
- PubChem CID
- 50590
Physical-chemical properties
- Molecular Formula
- C14H14ClNO3
- Molar Mass
- 279.72 g/mol
- IUPAC Name
- N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide
Chemical Identifiers
- InChI
- InChI=1S/C14H14ClNO3/c15-10-2-1-3-11(8-10)16(13(17)9-4-5-9)12-6-7-19-14(12)18/h1-3,8-9,12H,4-7H2
- InChI Key
- KRZUZYJEQBXUIN-UHFFFAOYSA-N
Overview
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide (CAS 69581-33-5) is a specialized organic compound with distinct cyclopropane and oxolane structural features. This chlorinated aromatic amide compound, with the molecular formula C14H14ClNO3 and a molecular weight of 279.72 g/mol, represents an important class of synthetic organic intermediates used in various industrial applications. The compound features a unique structural combination of a 3-chlorophenyl group, a cyclopropanecarboxamide moiety, and a 2-oxooxolan-3-yl substituent, which contributes to its specific chemical properties and reactivity profile. The substance is classified under EC number 274-050-9 and presents significant safety considerations due to its acute toxicity profile. It carries hazard classifications of Acute Tox. 4 and Acute Tox. 3, indicating moderate to high acute toxicity risks, alongside Aquatic Acute 1 and Aquatic Chronic 1 classifications that highlight its environmental hazard potential. The compound requires careful handling protocols consistent with ADR Class 6.1 materials and displays the GHS06 (skull and crossbones) and GHS09 (environment) pictograms with a "Danger" signal word. Primary industrial applications include use as a chemical intermediate in pharmaceutical synthesis, specialty polymer production, and advanced materials manufacturing. The compound's structural similarity to other complex organic molecules like 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline makes it valuable in research applications involving heterocyclic chemistry and medicinal compound development. OYSI provides this specialized compound to qualified industrial customers throughout Europe, ensuring proper documentation and safety protocols for professional chemical applications.
Safety & Classification
Acute Tox. 4 *; Acute Tox. 3 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2761 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Cyprofuram (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is a synthetic organic compound with the molecular formula C14H14ClNO3 and CAS number 69581-33-5. This chlorinated aromatic amide features a cyclopropane carboxamide structure linked to a chlorophenyl group and an oxolane ring. With a molecular weight of 279.72 g/mol, it belongs to the class of substituted carboxamides and exhibits significant toxicity and environmental hazard properties.
What are the physicochemical properties of N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is a solid compound at room temperature with a molecular weight of 279.72 g/mol. Its structure contains both hydrophobic aromatic components and polar functional groups including the amide and oxolane moieties. The presence of the chlorine substituent and multiple ring systems influences its solubility characteristics and chemical stability. Specific physical parameters such as melting point and solubility require analytical determination.
What is N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide used for?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is primarily used as a research chemical and intermediate in pharmaceutical synthesis. Its unique structural features, including the cyclopropane ring and chlorophenyl substituent, make it valuable for medicinal chemistry applications and drug discovery programs. The compound may also serve as a building block for developing bioactive molecules or as a reference standard in analytical chemistry laboratories.
How to handle N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide safely?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide requires careful handling due to its Acute Toxicity Category 3 and 4 classifications. Use appropriate personal protective equipment including nitrile gloves, safety goggles, and lab coats. Work in a well-ventilated area or fume hood to avoid inhalation exposure. Avoid skin and eye contact. Wash hands thoroughly after handling and before eating or drinking. Keep containers tightly closed when not in use.
How to store N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide correctly?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from incompatible materials such as strong oxidizing agents and bases. Store separately from food, beverages, and animal feeds. Maintain storage temperature according to supplier specifications and ensure containers are properly labeled with hazard information and safety precautions.
What to do in case of contact with N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide?
In case of skin contact with N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide, immediately wash the affected area with plenty of soap and water for at least 15 minutes. If eye contact occurs, flush immediately with clean water for 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.
How to dispose of N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide properly?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide must be disposed of as hazardous waste according to local, national, and international regulations. Due to its acute toxicity and environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), it cannot be disposed of in regular waste streams. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Avoid releasing into sewers, waterways, or the environment. Follow all applicable waste management legislation.
How to transport N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is classified as ADR Class 6.1 (Toxic substances), Packing Group III for transportation. Packages must comply with ADR packaging requirements and bear appropriate hazard labels including the GHS06 skull and crossbones pictogram. Transportation documents must include proper shipping names and hazard classifications. Only trained personnel should handle shipments, and emergency response information must be readily available during transport.
Is N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide subject to special regulations?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is subject to CLP regulation classification with Danger signal word and specific hazard pictograms (GHS06, GHS09). It falls under REACH registration requirements for chemical substances. The compound is not currently identified as a Substance of Very High Concern (SVHC). Users must comply with workplace safety regulations, environmental protection laws, and transportation requirements. Regular safety data sheet updates and hazard communication are mandatory.
Where to buy N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide in Europe?
N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance. As experienced chemical suppliers, OYSI ensures proper packaging, labeling, and transportation according to ADR regulations. Contact OYSI directly for availability, specifications, and pricing information for research and industrial applications throughout Europe.
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N-(3-chlorophenyl)-N-(2-oxooxolan-3-yl)cyclopropanecarboxamide is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.