3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is an organofluorine compound with CAS number 61213-25-0 and molecular formula C12H10Cl2F3NO. This pyrrolidinone derivative contains chlorine and trifluoromethyl functional groups, giving it a molecular weight of 312.11 g/mol. It is classified as a hazardous substance with reproductive toxicity, acute toxicity, and environmental hazard properties requiring careful handling and regulatory compliance.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one has a molecular weight of 312.11 g/mol and contains multiple halogen atoms including chlorine and fluorine substituents. The presence of trifluoromethyl and chloromethyl groups typically confers low volatility and potential lipophilicity. As with most halogenated organic compounds, it likely exhibits limited water solubility but good solubility in organic solvents. Specific physical properties should be confirmed through technical data sheets.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is typically used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its pyrrolidinone structure with halogenated substituents makes it valuable for creating complex molecular frameworks in medicinal chemistry. The compound may serve as a building block for developing bioactive molecules, particularly those requiring fluorinated or chlorinated functional groups. Industrial applications are generally limited to specialized chemical manufacturing processes.

Safe handling of 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its skin sensitization properties. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and never eat, drink, or smoke while handling. Wash hands thoroughly after use and ensure emergency eyewash and shower facilities are readily accessible.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store separately from incompatible materials including strong oxidizers, bases, and reactive metals. Ensure storage areas have appropriate containment measures and are accessible only to trained personnel. Regular inventory checks help maintain container integrity and prevent degradation.

In case of skin contact with 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, flush with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always contact emergency services if symptoms develop or persist after exposure.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one must be disposed of through licensed hazardous waste contractors due to its environmental hazard classification and potential ecotoxicity. Never dispose of in regular waste streams, sewers, or soil. The waste requires classification under appropriate waste codes and may need special treatment due to halogen content. Contact authorized waste management companies for proper collection, treatment, and disposal according to local and EU waste regulations.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transport purposes. This classification requires appropriate packaging, labeling, and documentation during shipping. Packages must display proper hazard labels and shipping names. Transport should be conducted by qualified carriers familiar with dangerous goods regulations. Ensure proper segregation from incompatible materials and comply with quantity limitations for different transport modes.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is subject to EU REACH registration requirements and CLP classification as Repr. 1B, Acute Tox. 4, Skin Sens. 1, and environmental hazard categories. While not currently listed as an SVHC, its reproductive toxicity classification requires strict handling protocols. Companies must maintain safety data sheets, conduct risk assessments, and implement appropriate risk management measures. Import/export may require additional documentation depending on destination country regulations.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is available through OYSI, a leading European distributor of specialty chemicals. As an established supplier, OYSI provides technical support, proper documentation, and regulatory compliance assistance for this specialized compound. Contact OYSI directly for availability, technical specifications, and pricing information. Given the compound's hazardous nature, purchase requires appropriate business credentials and demonstrated capability for safe handling and use.