3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is an organofluorine compound with CAS number 61213-25-0 and molecular formula C12H10Cl2F3NO. This pyrrolidinone derivative contains multiple halogen substituents including chlorine and trifluoromethyl groups. With a molecular weight of 312.11 g/mol, it is classified as a hazardous substance requiring careful handling due to its reproductive toxicity, acute toxicity, skin sensitization potential, and environmental hazards.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is a halogenated organic compound with molecular formula C12H10Cl2F3NO and molecular weight 312.11 g/mol. The presence of multiple electronegative halogen atoms (chlorine and fluorine) significantly influences its physicochemical behavior. The trifluoromethyl group typically imparts lipophilicity and chemical stability, while the pyrrolidinone ring structure affects solubility characteristics. Specific physical properties such as melting point, boiling point, and solubility data require analytical determination.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is primarily used as an intermediate in pharmaceutical and fine chemical synthesis. The compound's unique structure containing pyrrolidinone core with halogen substituents makes it valuable for developing bioactive molecules. It may serve as a building block in medicinal chemistry research and drug development processes. Industrial applications typically involve its use in specialized organic synthesis reactions where the specific combination of functional groups provides desired reactivity patterns.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one requires strict safety protocols due to its classification as Repr. 1B, Acute Tox. 4, and Skin Sens. 1. Use appropriate respiratory protection, chemical-resistant gloves, and eye protection. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Pregnant women should not handle this substance due to reproductive toxicity concerns. Implement proper hygiene measures and emergency procedures before use.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed original containers to prevent moisture absorption and contamination. Store separately from oxidizing agents, strong bases, and reducing agents. Implement appropriate containment measures to prevent environmental release due to its aquatic toxicity classification. Ensure storage areas are equipped with spill containment systems and emergency response equipment.

Immediate action is required upon contact with 3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If eye contact occurs, flush immediately with clean water and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical care. Always consult a physician and provide the safety data sheet for proper medical treatment.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one must be disposed of through authorized hazardous waste disposal facilities due to its environmental and health hazards. Never dispose of this substance down drains or in regular waste streams due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Contact licensed waste management companies specializing in halogenated organic compounds. Follow local, national, and EU waste regulations including proper labeling, documentation, and chain of custody procedures for hazardous waste disposal.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. Transportation requires appropriate UN-specification packaging and proper dangerous goods documentation. Vehicles must carry appropriate emergency equipment and drivers need ADR certification. Packages must be properly marked, labeled with GHS pictogramms (GHS07, GHS08, GHS09), and accompanied by transport documents specifying the hazard class and emergency response information.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is subject to multiple regulatory frameworks including REACH registration requirements and CLP classification as a hazardous substance. While not currently listed as an SVHC, its Repr. 1B classification subjects it to strict authorization and restriction considerations. Companies must comply with occupational exposure limits, environmental discharge restrictions, and proper safety data sheet provision. Regular regulatory monitoring is essential as classification and restrictions may change based on ongoing risk assessments.

3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance, proper documentation, and technical support. As a specialized fine chemical, availability may be limited and typically supplied to qualified industrial customers with appropriate handling capabilities. Contact OYSI directly for current availability, specifications, and ordering information for this regulated substance.