Formonitrile

CHN

formonitrile

CAS74-90-8
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
74-90-8
EC Number
200-821-6
UN Number
1051
Index Number
006-006-01-7
PubChem CID
768

Physical-chemical properties

Molecular Formula
CHN
Molar Mass
27.02 g/mol
IUPAC Name
formonitrile

Chemical Identifiers

InChI
InChI=1S/CHN/c1-2/h1H
InChI Key
LELOWRISYMNNSU-UHFFFAOYSA-N

Overview

Formonitrile (CAS 74-90-8) is a highly toxic nitrile compound with exceptional reactivity and industrial significance as a chemical intermediate. This simple yet potent chemical substance, also known by its IUPAC name formonitrile, represents one of the most hazardous nitrile compounds in industrial chemistry. With its molecular formula CHN and relatively low molecular weight of 27.025 g/mol, formonitrile exhibits properties that make it both valuable and extremely dangerous in chemical processing applications. The compound carries the highest level of safety warnings, classified under multiple acute toxicity categories and bearing the "Danger" signal word along with GHS06 and GHS09 pictograms, indicating both acute toxicity and environmental hazards. The substance's classification as Acute Tox. 1 and Acute Tox. 2 across different exposure routes, combined with its Aquatic Acute 1 and Aquatic Chronic 1 environmental classifications, underscores the critical importance of proper handling protocols and containment measures. Its ADR classification of 6.1 further emphasizes its status as a toxic substance requiring specialized transportation and storage conditions. Unlike related compounds such as zinc dicyanide or 2-hydroxy-2-methylpropanenitrile, formonitrile's extreme reactivity and toxicity profile demands the most stringent safety measures throughout the supply chain. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, specialty chemical production, and research applications where its unique molecular structure provides specific reactivity patterns. The compound also serves specialized roles in analytical chemistry and as a building block for more complex nitrile-containing molecules. OYSI maintains availability of formonitrile through its European distribution network, ensuring compliance with all relevant safety regulations and transportation requirements for qualified industrial customers.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1051
ADR Class6.1
Packing GroupI
Tunnel CodeD
Proper Shipping NameCyanwasserstoff, stabilisiert, Wasser < 3 %, flüssig
Marine PollutantNo

Frequently Asked Questions

What is formonitrile?

Formonitrile is a highly toxic chemical compound with the molecular formula CHN and CAS number 74-90-8. Also known as hydrogen cyanide, it has a molecular weight of 27.025 g/mol and represents one of the most dangerous chemical substances due to its extreme toxicity. This compound is classified under multiple acute toxicity categories and poses significant environmental hazards to aquatic life.

What are the physicochemical properties of formonitrile?

Formonitrile is a colorless gas at room temperature with a characteristic bitter almond odor, though not everyone can detect this smell. It is highly soluble in water and organic solvents, with a boiling point of 25.6°C and excellent miscibility properties. The compound is lighter than air and can form explosive mixtures with oxygen under certain conditions.

What is formonitrile used for?

Formonitrile serves as a precursor in the synthesis of various chemical compounds, particularly in pharmaceutical and chemical manufacturing processes. It is used in electroplating, metal cleaning, and as a fumigant in certain industrial applications. Due to its extreme toxicity, its use is strictly regulated and limited to specialized industrial processes under controlled conditions.

How to handle formonitrile safely?

Formonitrile requires extreme safety precautions due to its Acute Toxicity Category 1 and 2 classifications. Personnel must wear full-face respiratory protection, chemical-resistant gloves, and complete body protection. Work must be conducted in well-ventilated areas or under fume hoods, with emergency shower and eyewash stations immediately accessible. Only trained professionals should handle this substance.

How to store formonitrile correctly?

Formonitrile must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and incompatible materials. Storage areas should be equipped with appropriate detection systems and emergency response equipment. The compound should be kept away from acids, bases, and oxidizing agents to prevent dangerous reactions. Access must be restricted to authorized personnel only.

What to do in case of contact with formonitrile?

Formonitrile exposure requires immediate emergency response due to its extreme toxicity. For skin contact, remove contaminated clothing and flush with water for at least 15 minutes. In case of inhalation, move the person to fresh air immediately and provide oxygen if available. Seek immediate medical attention for any exposure. Emergency services should be contacted without delay.

How to dispose of formonitrile appropriately?

Formonitrile disposal must comply with hazardous waste regulations due to its extreme toxicity and environmental impact on aquatic ecosystems. The substance cannot be disposed of in regular waste streams and requires specialized treatment by licensed hazardous waste disposal companies. Neutralization or incineration at authorized facilities is typically required, following local and international environmental protection standards.

How to transport formonitrile?

Formonitrile is classified as ADR Class 6.1 (toxic substances) Packing Group I, indicating maximum danger level for transport. Transportation requires specialized packaging, proper labeling with GHS06 and GHS09 pictograms, and compliance with dangerous goods regulations. Only certified carriers with appropriate equipment and training can transport this substance, following strict documentation and safety protocols.

Is formonitrile subject to particular regulations?

Formonitrile is subject to extensive regulatory oversight under CLP regulation with 'Danger' signal word and multiple hazard classifications including acute toxicity and aquatic toxicity. While not currently listed as SVHC under REACH, its extreme toxicity means it falls under strict occupational health and safety regulations. Special permits and safety protocols are typically required for handling and use.

Where to buy formonitrile in Europe?

Formonitrile can be sourced through OYSI, a European distributor specializing in technical chemical products. Due to the extreme hazard classification of this substance, procurement requires proper authorization, safety documentation, and compliance with regulatory requirements. OYSI ensures proper handling, packaging, and delivery according to ADR transportation regulations and safety standards for European customers.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.