Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is an organic chemical compound with the molecular formula C18H17NO3 and CAS number 163520-33-0. This oxazole derivative features a five-membered heterocyclic ring containing nitrogen and oxygen atoms, substituted with two phenyl groups and an ethyl carboxylate group. With a molecular weight of 295.3 g/mol, it belongs to the class of heterocyclic compounds commonly used in pharmaceutical and chemical research applications.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is a solid organic compound at room temperature with a molecular weight of 295.3 g/mol. As an ethyl ester derivative of an oxazole carboxylic acid, it typically exhibits limited water solubility but good solubility in organic solvents such as ethanol, methanol, and dichloromethane. The compound's stability and specific physical characteristics like melting point and appearance may vary depending on purity and storage conditions.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is primarily used as an intermediate in pharmaceutical research and organic synthesis. This oxazole derivative serves as a building block for developing more complex molecules, particularly in medicinal chemistry applications. It may be utilized in the synthesis of bioactive compounds, drug candidates, or specialized chemical products. The compound's unique structure makes it valuable for researchers working on heterocyclic chemistry and pharmaceutical development projects.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate requires careful handling due to its Acute Tox. 4 and Skin Sens. 1 classifications. Always wear appropriate personal protective equipment including nitrile gloves, safety glasses, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent skin and eye contact, and avoid ingestion. The compound may cause skin sensitization, so handle with extra caution to prevent dermal exposure and potential allergic reactions.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight. Keep the compound at room temperature or below, protected from moisture and incompatible materials. Store away from heat sources, oxidizing agents, and strong acids or bases. Ensure proper labeling with hazard information and maintain inventory records. Given its environmental hazard classification, prevent release to the environment during storage and handling.

In case of skin contact with ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Given the compound's skin sensitization potential, monitor for allergic reactions and consult a physician if symptoms develop.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate must be disposed of through licensed hazardous waste disposal facilities due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). Do not release to sewers, waterways, or the environment. Collect waste in appropriate containers, properly labeled with contents and hazard information. Contact certified waste management companies for collection and treatment. Follow local, national, and EU regulations for hazardous chemical waste disposal, including waste classification codes.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-approved packaging suitable for Class 9 materials, ensure proper hazard labels are affixed, and complete required transport documentation. The relatively lower hazard level of Packing Group III allows for less stringent transport requirements compared to higher hazard classifications.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is subject to standard EU chemical regulations including REACH and CLP. The compound is not classified as a Substance of Very High Concern (SVHC), but must comply with classification, labeling, and packaging requirements under CLP regulation. As a chemical with hazardous properties, it requires safety data sheets, proper hazard communication, and adherence to occupational exposure limits where applicable. Import/export may require additional documentation depending on quantities and destinations.

Ethyl 5,5-diphenyl-4H-1,2-oxazole-3-carboxylate is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound to research institutions, pharmaceutical companies, and chemical manufacturers across Europe. As a professional chemical distributor, OYSI ensures proper handling, storage, and documentation compliance with European regulations. Contact OYSI directly for availability, specifications, and pricing information for your specific research or industrial application requirements.