Dibromomethane

CH2Br2

dibromomethane

CAS74-95-3
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
74-95-3
EC Number
200-824-2
UN Number
2664
Index Number
602-003-00-8
PubChem CID
3024

Physical-chemical properties

Molecular Formula
CH2Br2
Molar Mass
173.83 g/mol
IUPAC Name
dibromomethane

Chemical Identifiers

InChI
InChI=1S/CH2Br2/c2-1-3/h1H2
InChI Key
FJBFPHVGVWTDIP-UHFFFAOYSA-N

Overview

Dibromomethane (CAS 74-95-3) is a halogenated organic solvent with high density and excellent solvating properties for various chemical applications. This colorless, dense liquid belongs to the methane derivative family and serves as an important intermediate in organic synthesis and specialized industrial processes. With its molecular formula CH2Br2 and molecular weight of 173.83 g/mol, dibromomethane exhibits unique physical properties that make it valuable for specific technical applications where conventional solvents prove inadequate. The compound presents moderate toxicity concerns, classified as Acute Tox. 4 under GHS regulations, requiring appropriate handling procedures and personal protective equipment during industrial use. Its aquatic chronic toxicity classification necessitates careful environmental management and proper disposal protocols. The substance falls under ADR Class 6.1 for transportation, reflecting its toxic nature and requiring specialized logistics considerations. Dibromomethane finds primary applications in pharmaceutical synthesis as a methylating agent and chemical intermediate, particularly in the production of specialized organic compounds. The electronics industry utilizes it in certain cleaning and degreasing operations where its unique solvent properties prove advantageous. Additionally, it serves as a density gradient medium in laboratory separations and analytical procedures. Unlike related compounds such as bromomethylbenzene, which primarily serves in aromatic synthesis, dibromomethane offers distinct advantages in aliphatic chemistry applications. The compound's stability under controlled conditions and its effectiveness in specialized reactions make it an essential component for manufacturers requiring high-purity chemical intermediates. OYSI maintains reliable supply chains for dibromomethane to support European industrial customers' technical requirements.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Aquatic Chronic 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2664
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameDibrommethan
Marine PollutantNo

Frequently Asked Questions

What is dibromomethane?

Dibromomethane is an organobromine compound with the chemical formula CH2Br2 and CAS number 74-95-3. This halogenated methane derivative has a molecular weight of 173.83 g/mol and appears as a colorless liquid at room temperature. It belongs to the family of dihalomethanes and is classified as a moderate health hazard under GHS regulations, carrying the warning signal word and GHS07 pictogram for its acute toxicity properties.

What are the physicochemical properties of dibromomethane?

Dibromomethane is a dense, colorless liquid with a sweet, chloroform-like odor at room temperature. It has a high density compared to water and exhibits limited water solubility but dissolves readily in organic solvents such as alcohol, ether, and acetone. The compound is non-flammable under normal conditions and has a relatively high boiling point due to the presence of two bromine atoms, making it stable under standard handling conditions.

What is dibromomethane used for?

Dibromomethane serves primarily as a laboratory reagent and chemical intermediate in organic synthesis reactions. It is commonly used in pharmaceutical manufacturing, agricultural chemical production, and as a solvent for specialized applications. The compound also finds use in analytical chemistry procedures and as a methylenating agent in various chemical processes. Its unique properties make it valuable in research and development applications requiring controlled reactivity.

How to handle dibromomethane safely?

Dibromomethane handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 4 classification. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact and ensure proper ventilation systems are operational. Emergency eyewash stations and safety showers should be readily accessible when working with this substance.

How to store dibromomethane correctly?

Dibromomethane storage requires cool, dry, well-ventilated areas away from direct sunlight and heat sources. Containers should be tightly sealed and stored in secondary containment to prevent environmental release. Keep away from incompatible materials such as strong bases and oxidizing agents. Storage areas must comply with local regulations for hazardous substances and include appropriate spill containment measures to address the compound's aquatic chronic toxicity classification.

What to do in case of contact with dibromomethane?

Skin contact with dibromomethane requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention if symptoms develop. In case of ingestion, do not induce vomiting and seek immediate medical assistance while providing safety data sheet information to healthcare providers.

How to dispose of dibromomethane properly?

Dibromomethane disposal must comply with local and national hazardous waste regulations as it cannot be disposed of through regular waste streams. The substance should be collected in appropriate containers and handed over to licensed hazardous waste disposal companies. Due to its aquatic chronic toxicity classification, prevent any release to water systems or soil. Consult local environmental authorities for specific disposal requirements and approved treatment facilities in your region.

How to transport dibromomethane?

Dibromomethane transport falls under ADR Class 6.1 (toxic substances) Packing Group III regulations for road transport in Europe. Packages must bear appropriate hazard labels and comply with UN packaging requirements for toxic liquids. Transport documentation must include proper shipping names, hazard classes, and emergency response information. Drivers require ADR training certification, and vehicles must carry appropriate emergency equipment as specified in transportation regulations.

Is dibromomethane subject to specific regulations?

Dibromomethane is subject to REACH regulation requirements in Europe, including registration obligations for importers and manufacturers. The substance falls under CLP regulation with mandatory hazard classification as Acute Tox. 4 and Aquatic Chronic 3. While not currently listed as a SVHC substance, users must comply with occupational exposure limits and environmental protection measures. Regular monitoring of regulatory updates is essential as classifications may change based on new scientific data.

Where to buy dibromomethane in Europe?

Dibromomethane is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across the continent. OYSI provides quality-assured dibromomethane with complete documentation including certificates of analysis, safety data sheets, and regulatory compliance information. As a professional chemical supplier, OYSI ensures proper packaging, labeling, and transport documentation to meet European chemical distribution standards and customer specifications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.