Benzo[e]pyrene

Benzo[e]pyrene is a polycyclic aromatic hydrocarbon (PAH) with the molecular formula C20H12 and CAS number 192-97-2. This organic compound has a molecular weight of 252.3 g/mol and consists of five fused benzene rings arranged in a specific configuration. It is classified as a carcinogenic substance (Category 1B) and poses significant environmental hazards to aquatic life. Benzo[e]pyrene is typically found as a byproduct of incomplete combustion processes and is considered a priority pollutant due to its persistence and potential health impacts.

Benzo[e]pyrene is a solid crystalline compound at room temperature, typically appearing as pale yellow crystals or powder. It has a very low water solubility due to its hydrophobic nature, making it practically insoluble in water but soluble in organic solvents such as benzene, toluene, and chloroform. The compound exhibits fluorescent properties and has a relatively high melting point. Its low volatility and lipophilic characteristics contribute to its bioaccumulation potential and environmental persistence in sediments and organic matter.

Benzo[e]pyrene is primarily used as a research chemical and analytical standard in environmental monitoring and toxicological studies. It serves as a reference material for developing analytical methods to detect PAH contamination in environmental samples, food products, and biological specimens. In academic and industrial research, it is utilized for studying carcinogenic mechanisms, environmental fate, and biodegradation processes. The compound is also employed in method validation for laboratories conducting environmental analysis and regulatory compliance testing for PAH contamination assessment.

Benzo[e]pyrene requires strict safety protocols due to its carcinogenic properties (Category 1B classification). Personnel must wear appropriate personal protective equipment including nitrile gloves, safety goggles, and laboratory coats, with respiratory protection recommended in powder form handling. Work should be conducted in well-ventilated areas or fume hoods to prevent inhalation exposure. Avoid skin contact, ingestion, and dust generation. All surfaces should be decontaminated after use, and hands must be thoroughly washed. Emergency procedures and safety data sheets should be readily accessible to all personnel.

Benzo[e]pyrene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Storage areas must be equipped with appropriate ventilation and spill containment measures. Keep containers properly labeled with hazard information and store separately from incompatible materials such as strong oxidizing agents. Access should be restricted to trained personnel only, and inventory records should be maintained. Storage facilities should comply with local regulations for carcinogenic substances and include appropriate fire suppression systems and emergency response equipment.

Benzo[e]pyrene exposure requires immediate action due to its carcinogenic nature. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes and remove contact lenses if easily removable. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and rinse mouth with water. Seek immediate medical attention in all cases and provide the safety data sheet to medical personnel.

Benzo[e]pyrene disposal must comply with local and national hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment through licensed waste management companies. Contaminated materials, including gloves, wipes, and containers, must be treated as hazardous waste. Incineration at high temperatures in authorized facilities is typically the preferred disposal method. All disposal activities must be documented, and waste manifests should be maintained according to regulatory requirements for carcinogenic substances.

Benzo[e]pyrene is classified under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, requiring specific transport protocols. Packages must be properly labeled with appropriate hazard labels and shipping documentation must include the correct technical name and UN identification. Transport should be conducted by trained personnel familiar with dangerous goods regulations. Vehicles must carry appropriate emergency response information and spill cleanup materials. The substance should be segregated from incompatible materials during transport and secured to prevent container damage or spillage during transit.

Benzo[e]pyrene is subject to comprehensive regulatory oversight under multiple frameworks. Under the CLP Regulation, it is classified as Carcinogen Category 1B with mandatory hazard labeling requirements. REACH registration requirements apply for importers and manufacturers above specified tonnage thresholds. Many countries have established occupational exposure limits and environmental quality standards for this compound. Additionally, it may be subject to restrictions under national chemical control laws and international conventions addressing persistent organic pollutants, requiring compliance monitoring and reporting for industrial users.

Benzo[e]pyrene is available through OYSI, a specialized European distributor of technical chemicals serving research institutions and industrial customers. As a controlled substance requiring proper licensing and safety protocols, procurement is typically limited to qualified laboratories and research facilities with appropriate handling capabilities. OYSI ensures regulatory compliance and provides necessary documentation including certificates of analysis and safety data sheets. Customers must demonstrate legitimate research or analytical purposes and maintain proper storage and handling facilities before purchase authorization. Contact OYSI directly for availability, specifications, and regulatory requirements.