5-nitro-2H-benzotriazole

5-nitro-2H-benzotriazole is an organic chemical compound with the molecular formula C6H4N4O2 and CAS number 2338-12-7. This substance belongs to the benzotriazole family, featuring a nitro group (-NO2) attached to the benzene ring at the 5-position. With a molecular weight of 164.12 g/mol, it appears as a crystalline solid with characteristic chemical properties typical of nitro-substituted aromatic heterocycles.

5-nitro-2H-benzotriazole is typically a yellowish to light brown crystalline solid at room temperature. The compound exhibits limited solubility in water but shows better solubility in organic solvents such as alcohols and acetone. Its melting point is relatively high due to the stable aromatic ring structure and intermolecular hydrogen bonding. The nitro group contributes to its polar character and influences its chemical reactivity.

5-nitro-2H-benzotriazole is primarily used as an intermediate in pharmaceutical synthesis and as a building block for specialty chemicals. It serves as a precursor in the manufacture of dyes, pigments, and optical brighteners. The compound also finds applications in the development of UV stabilizers and corrosion inhibitors. Its benzotriazole structure makes it valuable in research and development for creating new chemical entities with specific properties.

5-nitro-2H-benzotriazole should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation of dust particles. Avoid direct skin contact and wash hands thoroughly after handling. Keep away from heat sources, sparks, and open flames as a general precaution with organic compounds.

5-nitro-2H-benzotriazole should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep the substance away from incompatible materials such as strong oxidizing agents and reducing agents. Store at room temperature in original packaging with proper labeling. Ensure storage areas are equipped with appropriate spill containment measures and maintain good housekeeping practices.

In case of skin contact with 5-nitro-2H-benzotriazole, immediately wash the affected area with plenty of soap and water for at least 15 minutes. If eye contact occurs, rinse thoroughly with clean water for several minutes and remove contact lenses if present. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek medical attention. Always consult safety data sheets for specific guidance.

5-nitro-2H-benzotriazole waste must be disposed of according to local, national, and international environmental regulations. Contact licensed waste disposal companies that specialize in chemical waste management. Do not discharge into drains, soil, or water bodies. Small laboratory quantities may require special collection procedures, while larger amounts need professional hazardous waste disposal. Always check current waste classification codes and disposal requirements in your jurisdiction.

5-nitro-2H-benzotriazole falls under ADR Class 1 for transportation purposes, indicating it requires special handling during shipping. Proper packaging, labeling, and documentation are essential according to dangerous goods regulations. Use UN-approved packaging and ensure proper placarding of transport vehicles. Consult current ADR regulations and work with qualified dangerous goods transport specialists to ensure compliance with all applicable transportation requirements.

5-nitro-2H-benzotriazole is not classified as a Substance of Very High Concern (SVHC) under REACH regulation. However, it must comply with standard REACH registration requirements if manufactured or imported in quantities above one tonne per year. Users should maintain safety data sheets, conduct chemical safety assessments where required, and follow good industrial hygiene practices. Always check current regulatory status as classifications may be updated.

5-nitro-2H-benzotriazole is available through OYSI, a European distributor specializing in technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with proper documentation and regulatory compliance. Contact OYSI's technical sales team for availability, specifications, and delivery options. They can provide certificates of analysis, safety data sheets, and technical support to ensure the product meets your specific application requirements.