3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine
C14H8Cl2N4
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Identification
- CAS Number
- 74115-24-5
- EC Number
- 277-728-2
- UN Number
- 3077
- Index Number
- 613-341-00-0
- PubChem CID
- 73670
Physical-chemical properties
- Molecular Formula
- C14H8Cl2N4
- Molar Mass
- 303.10 g/mol
- IUPAC Name
- 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine
Chemical Identifiers
- InChI
- InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H
- InChI Key
- UXADOQPNKNTIHB-UHFFFAOYSA-N
Overview
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine (CAS 74115-24-5) is a heterocyclic nitrogen compound featuring chlorinated phenyl substituents and specialized electronic properties. This specialized tetrazine derivative represents an important class of nitrogen-rich heterocyclic compounds widely utilized in advanced chemical applications. With its molecular formula C14H8Cl2N4 and molecular weight of 303.1 g/mol, this compound exhibits unique electronic characteristics due to its tetrazine core structure combined with two 2-chlorophenyl substituents. The presence of four nitrogen atoms in the six-membered ring system provides distinctive reactivity patterns, while the chlorinated aromatic rings contribute to enhanced stability and specific binding properties. From a safety perspective, 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is classified under GHS pictogram GHS09 with a "Warning" signal word, indicating moderate hazard potential. The primary safety concern relates to its Aquatic Chronic 1 classification, requiring careful environmental handling protocols. As a Class 9 substance under ADR regulations, it necessitates appropriate transport documentation and packaging procedures during distribution. The compound finds applications in pharmaceutical intermediate synthesis, particularly in the development of bioactive molecules where tetrazine chemistry provides valuable synthetic pathways. Additionally, it serves in specialty materials research, including the development of energetic materials and advanced polymer systems. Unlike simpler compounds such as 2-methylpropyl 2-(oxiran-2-yl)acetate, this tetrazine derivative offers more complex reactivity profiles suitable for sophisticated chemical transformations. Industrial applications also extend to analytical chemistry, where its unique spectroscopic properties make it valuable as a reference standard or analytical reagent in specialized testing procedures. OYSI maintains reliable supply chains for 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine, ensuring consistent availability for European industrial and research applications.
Safety & Classification
Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Very toxic to aquatic life with long lasting effects.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | Clofentezin (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is an organic heterocyclic compound with the molecular formula C14H8Cl2N4 and CAS number 74115-24-5. This tetrazine derivative contains two chlorinated phenyl groups attached to a tetrazine ring core. With a molecular weight of 303.1 g/mol, it belongs to the class of nitrogen-rich heterocycles and is primarily classified as having chronic aquatic toxicity (Aquatic Chronic 1).
What are the physico-chemical properties of 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is a solid organic compound with a molecular weight of 303.1 g/mol. The presence of two chlorine atoms and the tetrazine ring structure influence its physical properties. As a substituted tetrazine, it typically exhibits low solubility in water but may be soluble in organic solvents. The compound's stability and reactivity are characteristic of tetrazine derivatives, which are known for their unique electronic properties.
What is 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine used for?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is primarily used in research and specialty chemical applications. Tetrazine compounds are valuable in organic synthesis, particularly in bioorthogonal chemistry and click reactions. This specific derivative may be utilized in pharmaceutical research, materials science, or as an intermediate in the synthesis of more complex molecules. Its unique structure makes it suitable for applications requiring specific electronic or coordination properties.
How to handle 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine safely?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine should be handled with standard laboratory safety precautions due to its Warning classification. Wear appropriate personal protective equipment including safety goggles, gloves, and lab coats. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact. Handle the compound with clean, dry tools and prevent environmental release due to its aquatic toxicity classification (Aquatic Chronic 1).
How to store 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine correctly?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine should be stored in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents or reducing agents. Due to its environmental hazard classification (GHS09), ensure secure storage to prevent accidental release. Maintain proper inventory records and label containers clearly with hazard information.
What to do in case of contact with 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine?
In case of skin contact with 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, flush thoroughly with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always have safety data sheets readily available and contact poison control if necessary.
How to dispose of 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine properly?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine must be disposed of as hazardous waste due to its environmental classification (Aquatic Chronic 1, GHS09). Never dispose of this compound down drains or into the environment. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Follow local and national regulations for chemical waste management. Collect waste in appropriate containers, properly labeled, and maintain disposal records as required by environmental regulations.
How to transport 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation for shipping. Use UN-approved packaging suitable for Class 9 materials and ensure proper hazard labels are affixed. Transport documentation must include the correct shipping name, UN number, and hazard class. Follow ADR regulations for quantity limitations and vehicle requirements.
Is 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine subject to specific regulations?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The compound is classified under GHS with Warning signal word and environmental hazard pictogram (GHS09). It is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with workplace safety regulations, environmental protection laws, and proper classification, labeling, and packaging requirements under CLP.
Where to buy 3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine in Europe?
3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides high-quality chemical products to research institutions, pharmaceutical companies, and industrial users across Europe. As a professional chemical distributor, OYSI ensures proper handling, storage, and documentation compliance with European regulations. Contact OYSI directly for availability, technical specifications, safety documentation, and delivery options for your specific requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.