2-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione

2-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione is a complex organic compound with the molecular formula C19H15FN2O4 and CAS number 103361-09-7. This fluorinated benzoxazine derivative has a molecular weight of 354.3 g/mol and features both benzoxazin and tetrahydroisoindole functional groups. The compound is classified as a reproductive toxicant (Category 2) and poses acute and chronic aquatic hazards, requiring careful handling in professional applications.

This compound exhibits typical properties of fluorinated organic molecules with its molecular weight of 354.3 g/mol and complex aromatic structure. The presence of fluorine, nitrogen, and oxygen heteroatoms influences its polarity and potential hydrogen bonding capabilities. The benzoxazine and tetrahydroisoindole ring systems contribute to its structural rigidity. Specific physical properties such as melting point, boiling point, and solubility data would require detailed analytical characterization for precise determination.

This compound is primarily used in pharmaceutical research and development as an intermediate or active pharmaceutical ingredient. Its complex structure containing fluorine and multiple nitrogen-containing heterocycles makes it valuable in medicinal chemistry applications. The benzoxazine scaffold is commonly found in bioactive compounds with potential therapeutic properties. It may also serve as a building block for the synthesis of more complex pharmaceutical compounds or as a research tool in chemical biology studies.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and laboratory coats due to its reproductive toxicity classification (Repr. 2). Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and prevent release to the environment given its aquatic toxicity. Use proper laboratory techniques, ensure adequate training for handlers, and maintain emergency procedures readily available.

Proper storage requires a cool, dry, well-ventilated area away from incompatible materials and ignition sources. The compound should be kept in tightly sealed original containers, protected from moisture and light. Given its environmental hazards, storage areas must have appropriate containment measures to prevent environmental release. Maintain segregation from oxidizing agents and other reactive chemicals. Regular inventory checks and proper labeling according to GHS requirements (GHS08, GHS09 pictograms) are essential.

Immediate first aid measures include removing contaminated clothing and rinsing affected skin thoroughly with water for at least 15 minutes. For eye contact, flush with clean water for 15-20 minutes while holding eyelids open. If inhaled, move the person to fresh air and monitor breathing. Given the reproductive toxicity concerns, seek immediate medical attention in all exposure cases and provide the safety data sheet to medical personnel for proper treatment guidance.

Disposal must comply with local, national, and international waste regulations due to its environmental hazard classification. The compound requires treatment as hazardous waste and should never be discharged to sewers or the environment. Contact licensed waste disposal contractors specializing in pharmaceutical and hazardous chemical waste. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Maintain proper documentation of waste disposal activities and chain of custody records.

Transportation follows ADR Class 9 regulations as a miscellaneous dangerous substance in Packing Group III, indicating moderate danger level. Proper packaging must meet UN specification requirements with appropriate marking and labeling including GHS pictograms (GHS08, GHS09). Transport documents must include proper shipping names, hazard classes, and emergency contact information. Ensure vehicle compatibility and driver training for hazardous materials transport according to ADR regulations.

This compound is subject to REACH registration requirements and CLP classification regulations within the European Union. Its reproductive toxicity (Repr. 2) and environmental hazard classifications trigger specific regulatory obligations including safety data sheet requirements, workplace exposure limits, and environmental protection measures. While not currently listed as an SVHC, regular monitoring of regulatory updates is recommended. Import/export may require additional permits depending on jurisdiction and intended use.

OYSI serves as a reliable European distributor for this specialized chemical compound, providing professional-grade materials with proper documentation and regulatory compliance. As an established chemical distributor, OYSI ensures appropriate handling, storage, and transport according to European regulations. Professional customers can contact OYSI for availability, technical specifications, and regulatory documentation. Given the specialized nature of this compound, advance ordering and proper qualification of end-use applications may be required.