3-methylbutan-1-amine

3-methylbutan-1-amine is a primary aliphatic amine with the molecular formula C5H13N and CAS number 107-85-7. This branched-chain amine features a five-carbon backbone with a methyl substituent at the third position and an amino group at the terminal carbon. With a molecular weight of 87.16 g/mol, it belongs to the class of alkyl amines commonly used as chemical intermediates in organic synthesis and industrial applications.

3-methylbutan-1-amine is a colorless to pale yellow liquid at room temperature with a characteristic fishy, ammonia-like odor typical of primary amines. The compound is highly soluble in water due to its ability to form hydrogen bonds through the amino group. It exhibits basic properties with a pKa around 10-11, readily forming salts with acids. The substance has a boiling point of approximately 95-97°C and is volatile under normal conditions.

3-methylbutan-1-amine serves as a versatile chemical intermediate in pharmaceutical synthesis, particularly for developing active pharmaceutical ingredients and drug precursors. It is utilized in the production of specialty chemicals, surfactants, and corrosion inhibitors. The compound also finds applications in polymer chemistry as a curing agent for epoxy resins and in the synthesis of quaternary ammonium compounds used in various industrial formulations and chemical manufacturing processes.

3-methylbutan-1-amine requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation of vapors. Avoid contact with skin, eyes, and clothing. Use non-sparking tools and ensure proper grounding when transferring the material. Keep away from heat sources, sparks, and open flames as the substance is flammable.

3-methylbutan-1-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from oxidizing agents, acids, and incompatible materials that could cause dangerous reactions. Storage temperatures should be maintained below 25°C when possible. Containers must be properly labeled and stored in secondary containment to prevent spills. Ensure storage areas have appropriate fire suppression systems due to the flammable nature of the compound.

3-methylbutan-1-amine contact requires immediate action depending on the exposure route. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets and contact poison control centers when necessary.

3-methylbutan-1-amine disposal must comply with local, national, and EU waste regulations as a chemical waste. The substance should be collected in appropriate containers and delivered to licensed waste disposal facilities specializing in organic chemical waste. Do not discharge into drains, waterways, or soil. Small quantities may be neutralized with appropriate acids under controlled conditions by qualified personnel. Always consult local environmental authorities and follow waste classification codes for proper disposal documentation.

3-methylbutan-1-amine is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations compliance. The substance must be packaged in UN-approved containers with proper labeling and documentation. Transport vehicles need appropriate placarding and emergency equipment. Drivers must possess ADR certification for dangerous goods transport. Shipping papers must include proper shipping names, hazard classes, and emergency contact information. Special handling procedures apply during loading, transport, and unloading operations.

3-methylbutan-1-amine is subject to REACH regulation requiring registration for import/manufacture above one tonne annually in the EU. The substance must comply with CLP classification and labeling requirements, though it currently shows no specific GHS classifications. It is not listed as a Substance of Very High Concern (SVHC). Users must maintain safety data sheets and ensure proper worker protection measures. National chemical regulations may impose additional requirements for handling, storage, and use in specific applications.

3-methylbutan-1-amine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides this chemical intermediate to pharmaceutical, specialty chemical, and manufacturing industries with appropriate documentation and regulatory compliance. The company ensures proper packaging, labeling, and transport arrangements according to ADR requirements. Contact OYSI directly for availability, specifications, and delivery options tailored to your specific industrial applications and volume requirements.