(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

C14H10ClNO4

CAS66938-41-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

Consulting for (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
66938-41-8
EC Number
423-290-4
UN Number
3077
Index Number
606-061-00-5
PubChem CID
736109

Physical-chemical properties

Molecular Formula
C14H10ClNO4
Molar Mass
291.68 g/mol
IUPAC Name
(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone

Chemical Identifiers

InChI
InChI=1S/C14H10ClNO4/c1-20-13-6-5-10(8-12(13)16(18)19)14(17)9-3-2-4-11(15)7-9/h2-8H,1H3
InChI Key
BBKNLCMVMVDRJA-UHFFFAOYSA-N

Overview

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone (CAS 66938-41-8) is an aromatic ketone compound featuring chlorinated and nitrated benzene rings with methoxy substitution. This specialized organic compound belongs to the benzophenone family, characterized by its distinctive molecular structure containing both electron-withdrawing and electron-donating substituents. The presence of the chlorine atom on one phenyl ring, combined with the methoxy and nitro groups on the other, creates a unique reactivity profile that makes it valuable in various synthetic applications. With a molecular formula of C14H10ClNO4 and molecular weight of 291.68 g/mol, this compound exhibits specific chemical properties that distinguish it from related aromatic ketones. The compound requires careful handling due to its classification as a Category 2 mutagen and its acute and chronic aquatic toxicity. Safety protocols must include appropriate personal protective equipment, particularly respiratory protection, as indicated by the GHS08 health hazard pictogram. The environmental hazard classification (GHS09) emphasizes the importance of proper containment and disposal procedures to prevent aquatic contamination. In industrial applications, (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone serves as an important synthetic intermediate in pharmaceutical manufacturing and specialty chemical production. Its unique substitution pattern makes it particularly valuable in the synthesis of complex organic molecules where selective reactivity is required. The compound shares certain structural similarities with other substituted aromatic compounds such as propan-2-yl N-(3-chlorophenyl)carbamate, though each maintains distinct reactivity profiles. OYSI maintains reliable supply chains for this technical-grade chemical compound, ensuring consistent availability for European industrial customers requiring high-quality aromatic ketone intermediates.

Safety & Classification

Warning
Classification:

Muta. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name(3-Chlorphenyl)-(4-methoxy-3-nitrophenyl)methanon
Marine PollutantNo

Frequently Asked Questions

What is (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is an organic chemical compound with the molecular formula C14H10ClNO4 and CAS number 66938-41-8. This ketone derivative has a molecular weight of 291.68 g/mol and contains both chlorine and nitro functional groups. It is classified as a mutagenic substance and poses environmental hazards to aquatic life. The compound requires careful handling due to its potential health and environmental risks.

What are the physicochemical properties of (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is a solid organic compound at room temperature with a molecular weight of 291.68 g/mol. The substance contains aromatic rings with chloro, methoxy, and nitro substituents, which influence its physical properties. Its solubility characteristics depend on the polarity of solvents, with the methoxy group providing some polar character while the aromatic system contributes to hydrophobic properties.

What is (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone used for?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is primarily used as a chemical intermediate in organic synthesis and pharmaceutical research. Its ketone functionality and aromatic substituents make it valuable for developing more complex molecular structures. The compound may serve in the synthesis of pharmaceutical compounds, agrochemicals, or other specialty chemicals. Its specific applications depend on the desired end products in various industrial processes.

How to handle (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone safely?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone must be handled with appropriate personal protective equipment due to its mutagenic properties (Muta. 2). Use chemical-resistant gloves, safety goggles, and protective clothing when handling this substance. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and implement strict hygiene measures. Follow all safety data sheet recommendations and ensure personnel are properly trained.

How to store (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone correctly?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protect from light and moisture. Store separately from oxidizing agents, reducing agents, and other reactive chemicals. Ensure storage areas have appropriate containment measures to prevent environmental release, considering its aquatic toxicity classification. Maintain proper labeling and inventory records.

What to do in case of contact with (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone?

Immediate decontamination is essential after contact with (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water. In case of eye contact, flush immediately with plenty of clean water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, especially considering the substance's mutagenic properties.

How to dispose of (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone appropriately?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone must be disposed of as hazardous waste through licensed waste management companies. Due to its mutagenic and aquatic toxicity properties, it cannot be disposed of in regular waste streams or sewers. Follow local and national regulations for hazardous waste disposal. Consider waste minimization strategies and recovery options where feasible. Maintain proper documentation of disposal activities for regulatory compliance.

How to transport (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Use UN-approved packaging and ensure proper marking with hazard labels. Transport vehicles must comply with ADR requirements, and drivers need appropriate training for dangerous goods transport.

Is (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone subject to specific regulations?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is subject to REACH regulation and CLP classification requirements in Europe. It is classified as Muta. 2 (mutagenic) and carries aquatic toxicity classifications, requiring appropriate hazard communication. While not currently listed as SVHC, its mutagenic properties require careful regulatory compliance. Suppliers must provide safety data sheets and ensure proper classification, labeling, and packaging according to CLP regulation.

Where to buy (3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone in Europe?

(3-chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone is available through OYSI, a specialized European distributor of chemical products. OYSI provides this compound with full regulatory compliance, including proper documentation and safety data sheets. As a professional chemical supplier, OYSI ensures quality standards and regulatory compliance for industrial and research customers across Europe. Contact OYSI directly for availability, specifications, and delivery options.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.